AP73A - Therapeautic nucleosides. - Google Patents

Therapeautic nucleosides. Download PDF

Info

Publication number
AP73A
AP73A APAP/P/1988/000085A AP8800085A AP73A AP 73 A AP73 A AP 73A AP 8800085 A AP8800085 A AP 8800085A AP 73 A AP73 A AP 73A
Authority
AP
ARIPO
Prior art keywords
substituted
formula
compound
halogen
hydroxy
Prior art date
Application number
APAP/P/1988/000085A
Other languages
English (en)
Other versions
AP8800085A0 (en
Inventor
Janet Litster Rideout
George Andrew Freeman
Sammy Ray Shaver
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878706176A external-priority patent/GB8706176D0/en
Publication of AP8800085A0 publication Critical patent/AP8800085A0/xx
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Application granted granted Critical
Publication of AP73A publication Critical patent/AP73A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
APAP/P/1988/000085A 1987-03-16 1988-03-15 Therapeautic nucleosides. AP73A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878706176A GB8706176D0 (en) 1987-03-16 1987-03-16 Therapeutic nucleosides
US13880887A 1987-12-28 1987-12-28

Publications (2)

Publication Number Publication Date
AP8800085A0 AP8800085A0 (en) 1988-02-01
AP73A true AP73A (en) 1990-03-01

Family

ID=26292019

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1988/000085A AP73A (en) 1987-03-16 1988-03-15 Therapeautic nucleosides.

Country Status (18)

Country Link
EP (1) EP0287215B1 (de)
JP (1) JPS63290894A (de)
AP (1) AP73A (de)
AU (1) AU601556B2 (de)
CA (1) CA1321387C (de)
DE (1) DE3872028T2 (de)
DK (1) DK140588A (de)
ES (1) ES2039615T3 (de)
FI (1) FI881216A (de)
GR (1) GR3005506T3 (de)
HU (1) HU199865B (de)
IL (1) IL85738A0 (de)
MC (1) MC1914A1 (de)
NO (1) NO881135L (de)
NZ (1) NZ223880A (de)
PH (1) PH24812A (de)
PL (1) PL271196A1 (de)
PT (1) PT86982B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8706176D0 (en) * 1987-03-16 1987-04-23 Wellcome Found Therapeutic nucleosides
US4804651A (en) * 1987-06-09 1989-02-14 Board Of Regents, The University Of Texas System Methods and compositions for the treatment of psoriasis
US5077280A (en) * 1988-04-12 1991-12-31 Brown University Research Foundation Treatment of viral infections
GB8902041D0 (en) * 1989-01-31 1989-03-22 Tanabe Seiyaku Co Antiviral agent and novel nucleoside
US5220003A (en) * 1991-03-29 1993-06-15 The Regents Of The University Of California Process for the synthesis of 2',3'-dideoxynucleosides
CA2103050A1 (en) * 1991-05-15 1992-11-16 Yung-Chi Cheng Determination of prodrugs metabolizable by the liver and therapeutic use thereof
RU2111970C1 (ru) * 1996-06-25 1998-05-27 Иван Игоревич Федоров 3'-оксимино-2',3'-дидезоксинуклеозиды

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468384A (en) * 1982-01-05 1984-08-28 The Research Foundation Of State University Of New York Method for the inhibition of the replication of DNA viruses with 5-substituted 2-pyrimidinone nucleosides
EP0217580A2 (de) * 1985-09-17 1987-04-08 The Wellcome Foundation Limited Therapeutische Nukleoside

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0199451B1 (de) * 1985-03-16 1996-03-06 The Wellcome Foundation Limited Therapeutische Nukleoside
PT82199B (pt) * 1985-03-16 1990-11-07 Wellcome Found Processo para a preparacao de nucleosidos antivirais e de composicoes farmaceuticas que os contem

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468384A (en) * 1982-01-05 1984-08-28 The Research Foundation Of State University Of New York Method for the inhibition of the replication of DNA viruses with 5-substituted 2-pyrimidinone nucleosides
EP0217580A2 (de) * 1985-09-17 1987-04-08 The Wellcome Foundation Limited Therapeutische Nukleoside

Also Published As

Publication number Publication date
DE3872028T2 (de) 1993-01-14
AU601556B2 (en) 1990-09-13
NZ223880A (en) 1991-06-25
NO881135D0 (no) 1988-03-15
EP0287215A2 (de) 1988-10-19
AU1318588A (en) 1988-09-15
FI881216A0 (fi) 1988-03-15
PH24812A (en) 1990-10-30
CA1321387C (en) 1993-08-17
GR3005506T3 (de) 1993-06-07
DE3872028D1 (en) 1992-07-23
PT86982B (pt) 1992-06-30
FI881216A (fi) 1988-09-17
DK140588D0 (da) 1988-03-15
AP8800085A0 (en) 1988-02-01
NO881135L (no) 1988-09-19
MC1914A1 (fr) 1989-04-06
IL85738A0 (en) 1988-08-31
EP0287215B1 (de) 1992-06-17
ES2039615T3 (es) 1993-10-01
HUT47591A (en) 1989-03-28
EP0287215A3 (en) 1990-01-10
DK140588A (da) 1988-09-17
JPS63290894A (ja) 1988-11-28
PT86982A (pt) 1988-04-01
HU199865B (en) 1990-03-28
PL271196A1 (en) 1988-12-08

Similar Documents

Publication Publication Date Title
EP0286425B1 (de) Therapeutische Nukleoside
EP0206497B1 (de) Therapeutische Nucleoside und deren Herstellung
GB2181128A (en) 3'-azidonucleosides
IE920702A1 (en) Antiviral nucleoside combination
EP0285432B1 (de) Therapeutische Nukleoside
US5071983A (en) Therapeutic nucleosides
AU637831B2 (en) Therapeutic necleosides
AP73A (en) Therapeautic nucleosides.
US5574149A (en) Method of treating HIV infections with 2',3'-dideoxy-3'-fluoro-5-chlorouridine
IE903519A1 (en) Therapeutic nucleosides
US5663154A (en) 2',3'-dideoxy-3'-fluoro-purine ribonucleosides
DE68914750T2 (de) Therapeutische Nucleoside.
US4920210A (en) 2,6-diaminopurine-9-β-D-2',3'-dideoxyribofuranoside
WO1988009332A1 (en) Therapeutic nucleosides
AP90A (en) Therapeutic nucleosides.
US5175274A (en) Therapeutic nucleosides
HU201953B (en) Process for producing new nucleoside derivatives and pharmaceutical compositions comprising same as active ingredient
CA1336821C (en) Therapeutic nucleosides
DD268705A5 (de) Verfahren zur herstellung von 6-substituierten 2'-3'-dideoxynucleosiden und deren derivaten
NZ217587A (en) 3'-azido nucleosides and derivatives and pharmaceutical composition