AP3480A - Phosphaplatins and their use for treatment of cancers - Google Patents

Phosphaplatins and their use for treatment of cancers

Info

Publication number
AP3480A
AP3480A AP2012006594A AP2012006594A AP3480A AP 3480 A AP3480 A AP 3480A AP 2012006594 A AP2012006594 A AP 2012006594A AP 2012006594 A AP2012006594 A AP 2012006594A AP 3480 A AP3480 A AP 3480A
Authority
AP
ARIPO
Prior art keywords
phosphaplatins
cancers
treatment
Prior art date
Application number
AP2012006594A
Other languages
English (en)
Other versions
AP2012006594A0 (en
Inventor
Rathindra N Bose
Original Assignee
Univ Ohio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44627266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3480(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Ohio filed Critical Univ Ohio
Publication of AP2012006594A0 publication Critical patent/AP2012006594A0/xx
Application granted granted Critical
Publication of AP3480A publication Critical patent/AP3480A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/245Bismuth; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AP2012006594A 2010-06-04 2011-06-02 Phosphaplatins and their use for treatment of cancers AP3480A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35151410P 2010-06-04 2010-06-04
PCT/US2011/038948 WO2011153365A1 (en) 2010-06-04 2011-06-02 Phosphaplatins and their use for treatment of cancers

Publications (2)

Publication Number Publication Date
AP2012006594A0 AP2012006594A0 (en) 2012-12-31
AP3480A true AP3480A (en) 2015-12-31

Family

ID=44627266

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2012006594A AP3480A (en) 2010-06-04 2011-06-02 Phosphaplatins and their use for treatment of cancers

Country Status (30)

Country Link
US (4) US9688709B2 (pl)
EP (1) EP2575802B1 (pl)
JP (1) JP5860872B2 (pl)
KR (1) KR101775410B1 (pl)
CN (6) CN103037859A (pl)
AP (1) AP3480A (pl)
AU (1) AU2011261381B2 (pl)
BR (1) BR112012030927B1 (pl)
CA (1) CA2800898C (pl)
CL (1) CL2012003416A1 (pl)
CO (1) CO6640302A2 (pl)
CY (1) CY1118466T1 (pl)
DK (1) DK2575802T3 (pl)
EA (1) EA021526B1 (pl)
ES (1) ES2606855T3 (pl)
HR (1) HRP20170225T1 (pl)
HU (1) HUE030249T2 (pl)
IL (1) IL223405B (pl)
LT (1) LT2575802T (pl)
MX (1) MX2012014174A (pl)
MY (1) MY162902A (pl)
NZ (1) NZ603952A (pl)
PL (1) PL2575802T3 (pl)
PT (1) PT2575802T (pl)
RS (1) RS55714B1 (pl)
SG (1) SG185722A1 (pl)
SI (1) SI2575802T1 (pl)
SM (1) SMT201700056B (pl)
WO (1) WO2011153365A1 (pl)
ZA (1) ZA201209007B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5860872B2 (ja) 2010-06-04 2016-02-16 オハイオ ユニバーシティー ホスファプラチン、及び癌治療のためのそれらの使用
EP2663301A1 (en) * 2011-01-12 2013-11-20 Ohio University Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof
WO2013052839A1 (en) * 2011-10-05 2013-04-11 Bose Rathindra N Efficient processes for large scale preparation of phosphaplatins antitumor agents
EP2763537B1 (en) * 2011-10-05 2018-01-10 Rathindra N. Bose Efficient processes for large scale preparation of phosphaplatins antitumor agents
DK2855496T3 (en) * 2012-05-24 2017-03-27 Phosplatin Therapeutics Llc PROCEDURES FOR SYNTHESIS AND PURIFICATION OF PHOSPHAPLATIN COMPOUNDS AND APPLICATIONS THEREOF
US9333211B2 (en) * 2013-02-22 2016-05-10 University Of Houston System Phosphaplatin mediated modulation of pigment epithelial derived factor and uses thereof
US20150231151A1 (en) * 2014-02-19 2015-08-20 University Of Houston System Compositions and methods for the treatment of neurodegenerative diseases
US11154529B2 (en) * 2016-04-06 2021-10-26 Phosplatin Therapeutics Inc. Phosphaplatin liquid formulations
EP3565561A4 (en) * 2017-01-06 2020-08-26 Phosplatin Therapeutics LLC PHOSPHAPLATIN COMPOUNDS AS THERAPEUTICS FOR THE TREATMENT OF BONE / BLOOD CANCER
CN111328330B (zh) * 2017-09-08 2024-03-08 普罗蒙托里治疗有限公司 作为免疫调节剂的磷铂化合物及其治疗用途
WO2022087173A1 (en) * 2020-10-20 2022-04-28 Phosplatin Therapeutics Inc. Phosphaplatin compounds as therapeutic agents selectively targeting highly glycolytic tumor cells and methods thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009021081A2 (en) * 2007-08-06 2009-02-12 Ohio University Phosphaplatins and their use in the treatment of cancers resistant to cisplatin and carboplatin

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234500A (en) 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4291027A (en) 1979-03-07 1981-09-22 Engelhard Minerals & Chemicals Corp. Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes
CA2017739A1 (en) 1989-07-18 1991-01-18 Leslie S. Hollis Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents
AUPR330201A0 (en) 2001-02-23 2001-03-22 University Of Sydney, The Metal complexes and therapeutic uses thereof
DE10314780A1 (de) 2003-03-19 2004-09-30 Ktb Tumorforschungsgesellschaft Mbh Proteinbindende Derivate von Platinkomplexen mit Cyclobutan-1,1-dicarboxylatliganden
AU2004235781A1 (en) * 2003-05-02 2004-11-18 Aronex Pharmaceuticals, Inc. Lipid platinum complexes and methods of use thereof
EP1644388A2 (en) 2003-06-27 2006-04-12 ODANI, Akira Bisphosphonate complexes
JPWO2009008345A1 (ja) 2007-07-06 2010-09-09 久雄 浴本 金属錯体化合物、これを有効成分とする癌治療剤組成物および該金属錯体化合物用の中間体
WO2011125911A1 (ja) * 2010-03-31 2011-10-13 国立大学法人金沢大学 金属錯体およびこれを有効成分として含有する抗がん剤
JP5860872B2 (ja) 2010-06-04 2016-02-16 オハイオ ユニバーシティー ホスファプラチン、及び癌治療のためのそれらの使用
EP2663301A1 (en) 2011-01-12 2013-11-20 Ohio University Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof
EP2763537B1 (en) * 2011-10-05 2018-01-10 Rathindra N. Bose Efficient processes for large scale preparation of phosphaplatins antitumor agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009021081A2 (en) * 2007-08-06 2009-02-12 Ohio University Phosphaplatins and their use in the treatment of cancers resistant to cisplatin and carboplatin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BOSE RATHINDRA N ET AL: "Non-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum-phosphato complexes towards human ovarian cancer cells.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105, no. 47, 25 November 2008 (2008-11-25), pages 18314 - 18319,1292 *
MISHUR ROBERT J ET AL: "Synthesis, X-ray crystallographic, and NMR characterizations of platinum(II) and platinum(IV) pyrophosphato complexes.", INORGANIC CHEMISTRY, vol. 47, no. 18, 15 September 2008 (2008-09-15), pages 7972 - 7982 *

Also Published As

Publication number Publication date
CA2800898A1 (en) 2011-12-08
HUE030249T2 (en) 2017-04-28
KR20130095244A (ko) 2013-08-27
DK2575802T3 (en) 2017-01-09
EA201270812A1 (ru) 2013-05-30
BR112012030927B1 (pt) 2021-09-21
CN108210516A (zh) 2018-06-29
CY1118466T1 (el) 2017-07-12
CN108409795A (zh) 2018-08-17
HRP20170225T1 (hr) 2017-04-07
US10385083B2 (en) 2019-08-20
CA2800898C (en) 2018-12-04
MX2012014174A (es) 2013-07-03
PT2575802T (pt) 2016-12-27
US9688709B2 (en) 2017-06-27
AU2011261381A1 (en) 2013-01-10
NZ603952A (en) 2014-07-25
US20130064902A1 (en) 2013-03-14
US20170327521A1 (en) 2017-11-16
US10759820B2 (en) 2020-09-01
US20170327522A1 (en) 2017-11-16
RS55714B1 (sr) 2017-07-31
JP2013529219A (ja) 2013-07-18
CN108186651A (zh) 2018-06-22
PL2575802T3 (pl) 2017-04-28
CO6640302A2 (es) 2013-03-22
AP2012006594A0 (en) 2012-12-31
AU2011261381B2 (en) 2015-04-02
EA021526B1 (ru) 2015-07-30
KR101775410B1 (ko) 2017-09-06
CN108299508A (zh) 2018-07-20
ES2606855T3 (es) 2017-03-28
EP2575802A1 (en) 2013-04-10
CN108392490A (zh) 2018-08-14
IL223405B (en) 2018-11-29
CL2012003416A1 (es) 2013-09-06
ZA201209007B (en) 2013-08-28
EP2575802B1 (en) 2016-11-16
WO2011153365A1 (en) 2011-12-08
JP5860872B2 (ja) 2016-02-16
SMT201700056B (it) 2017-03-08
LT2575802T (lt) 2016-12-27
BR112012030927A2 (pt) 2017-12-05
US10364264B2 (en) 2019-07-30
US20190315789A1 (en) 2019-10-17
CN103037859A (zh) 2013-04-10
SI2575802T1 (sl) 2017-03-31
SG185722A1 (en) 2013-01-30
MY162902A (en) 2017-07-31

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