AP2010005456A0 - Novel class of spiro piperidines for the treatmentof neurodegenerative diseases. - Google Patents
Novel class of spiro piperidines for the treatmentof neurodegenerative diseases.Info
- Publication number
- AP2010005456A0 AP2010005456A0 AP2010005456A AP2010005456A AP2010005456A0 AP 2010005456 A0 AP2010005456 A0 AP 2010005456A0 AP 2010005456 A AP2010005456 A AP 2010005456A AP 2010005456 A AP2010005456 A AP 2010005456A AP 2010005456 A0 AP2010005456 A0 AP 2010005456A0
- Authority
- AP
- ARIPO
- Prior art keywords
- treatmentof
- neurodegenerative diseases
- novel class
- spiro piperidines
- piperidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5042308P | 2008-05-05 | 2008-05-05 | |
| PCT/IB2009/051815 WO2009136350A1 (fr) | 2008-05-05 | 2009-05-04 | Nouvelle classe de spiro pipéridines pour le traitement de maladies neurodégénératives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2010005456A0 true AP2010005456A0 (en) | 2010-12-31 |
Family
ID=40902870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2010005456A AP2010005456A0 (en) | 2008-05-05 | 2009-05-04 | Novel class of spiro piperidines for the treatmentof neurodegenerative diseases. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20110046160A1 (fr) |
| EP (1) | EP2300484B1 (fr) |
| JP (1) | JP2011519913A (fr) |
| KR (1) | KR20110000749A (fr) |
| CN (1) | CN102083841A (fr) |
| AP (1) | AP2010005456A0 (fr) |
| AT (1) | ATE537178T1 (fr) |
| AU (1) | AU2009245322B2 (fr) |
| BR (1) | BRPI0912433A2 (fr) |
| CA (1) | CA2721786A1 (fr) |
| CO (1) | CO6321280A2 (fr) |
| CR (1) | CR11759A (fr) |
| DO (1) | DOP2010000317A (fr) |
| EA (1) | EA201001566A1 (fr) |
| EC (1) | ECSP10010597A (fr) |
| ES (1) | ES2375913T3 (fr) |
| IL (1) | IL208793A0 (fr) |
| MA (1) | MA32290B1 (fr) |
| MX (1) | MX2010012066A (fr) |
| NZ (1) | NZ588589A (fr) |
| SV (1) | SV2010003725A (fr) |
| WO (1) | WO2009136350A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| UA108363C2 (uk) | 2009-10-08 | 2015-04-27 | Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування | |
| CA2795877A1 (fr) * | 2010-04-09 | 2011-10-13 | Pfizer Inc. | Nouveaux composes sultame |
| EP2694521B1 (fr) | 2011-04-07 | 2015-11-25 | Merck Sharp & Dohme Corp. | Composés de dioxyde de thiadiazine fusionnée à la pyrrolidine en tant qu'inhibiteurs de bace, compositions et leur utilisation |
| EP2694489B1 (fr) | 2011-04-07 | 2017-09-06 | Merck Sharp & Dohme Corp. | Composés de dioxyde de thiadiazine condensés avec des dérivés oxacycliques en c5-c6 comme inhibiteurs de bace, compositions, et utilisation use |
| WO2013028670A1 (fr) | 2011-08-22 | 2013-02-28 | Merck Sharp & Dohme Corp. | Iminothiazines 2-spiro-substituées et leur mono- et dioxydes en tant qu'inhibiteurs bace, compositions et leur utilisation |
| EP3233799B1 (fr) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Ligands du récepteur d2 de la dopamine |
| WO2016100940A1 (fr) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Ligands des récepteurs dopaminergiques d2 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004031560D1 (de) * | 2004-01-08 | 2011-04-07 | Hoffmann La Roche | Diazaspiropiperidinderivate |
| JP2006044497A (ja) * | 2004-08-05 | 2006-02-16 | Toyota Motor Corp | 車輪情報処理装置 |
| AU2005295814A1 (en) * | 2004-10-13 | 2006-04-27 | Merck & Co., Inc. | Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of Alzhermer's disease |
| ATE550338T1 (de) * | 2005-07-18 | 2012-04-15 | Merck Sharp & Dohme | Spiropiperidininhibitoren von beta-secretase zur behandlung von alzheimer-krankheit |
| JP2010502705A (ja) * | 2006-09-07 | 2010-01-28 | メルク エンド カムパニー インコーポレーテッド | アルツハイマー病の治療用としてのスピロピペリジンベータセクレターゼ阻害剤 |
| CA2673888A1 (fr) * | 2007-01-04 | 2008-07-17 | Merck And Co., Inc. | Inhibiteurs de la beta-secretase de spiropiperidine bi-cyclique destines au traitement de la maladie d'alzheimer |
-
2009
- 2009-05-04 US US12/990,739 patent/US20110046160A1/en not_active Abandoned
- 2009-05-04 NZ NZ588589A patent/NZ588589A/en not_active IP Right Cessation
- 2009-05-04 AT AT09742523T patent/ATE537178T1/de active
- 2009-05-04 KR KR1020107024794A patent/KR20110000749A/ko not_active Application Discontinuation
- 2009-05-04 EP EP09742523A patent/EP2300484B1/fr active Active
- 2009-05-04 AP AP2010005456A patent/AP2010005456A0/xx unknown
- 2009-05-04 CA CA2721786A patent/CA2721786A1/fr not_active Abandoned
- 2009-05-04 ES ES09742523T patent/ES2375913T3/es active Active
- 2009-05-04 CN CN2009801261947A patent/CN102083841A/zh active Pending
- 2009-05-04 EA EA201001566A patent/EA201001566A1/ru unknown
- 2009-05-04 WO PCT/IB2009/051815 patent/WO2009136350A1/fr active Application Filing
- 2009-05-04 BR BRPI0912433A patent/BRPI0912433A2/pt not_active Application Discontinuation
- 2009-05-04 JP JP2011508035A patent/JP2011519913A/ja not_active Withdrawn
- 2009-05-04 AU AU2009245322A patent/AU2009245322B2/en not_active Ceased
- 2009-05-04 MX MX2010012066A patent/MX2010012066A/es not_active Application Discontinuation
-
2010
- 2010-10-18 IL IL208793A patent/IL208793A0/en unknown
- 2010-10-21 DO DO2010000317A patent/DOP2010000317A/es unknown
- 2010-10-26 CR CR11759A patent/CR11759A/es not_active Application Discontinuation
- 2010-11-05 MA MA33328A patent/MA32290B1/fr unknown
- 2010-11-05 SV SV2010003725A patent/SV2010003725A/es not_active Application Discontinuation
- 2010-11-09 EC EC2010010597A patent/ECSP10010597A/es unknown
- 2010-11-11 CO CO10141834A patent/CO6321280A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011519913A (ja) | 2011-07-14 |
| US20110046160A1 (en) | 2011-02-24 |
| DOP2010000317A (es) | 2010-11-15 |
| ATE537178T1 (de) | 2011-12-15 |
| KR20110000749A (ko) | 2011-01-05 |
| AU2009245322A1 (en) | 2009-11-12 |
| WO2009136350A1 (fr) | 2009-11-12 |
| CA2721786A1 (fr) | 2009-11-12 |
| EP2300484A1 (fr) | 2011-03-30 |
| CR11759A (es) | 2010-11-22 |
| EA201001566A1 (ru) | 2011-04-29 |
| AU2009245322B2 (en) | 2011-07-14 |
| BRPI0912433A2 (pt) | 2015-12-22 |
| SV2010003725A (es) | 2011-07-05 |
| IL208793A0 (en) | 2010-12-30 |
| NZ588589A (en) | 2012-07-27 |
| ECSP10010597A (es) | 2010-12-30 |
| ES2375913T3 (es) | 2012-03-07 |
| CN102083841A (zh) | 2011-06-01 |
| MX2010012066A (es) | 2010-12-06 |
| EP2300484B1 (fr) | 2011-12-14 |
| MA32290B1 (fr) | 2011-05-02 |
| CO6321280A2 (es) | 2011-09-20 |
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