HRP20171889T1 - Formulacije kombinacije darunavira - Google Patents

Formulacije kombinacije darunavira

Info

Publication number
HRP20171889T1
HRP20171889T1 HRP20171889TT HRP20171889T HRP20171889T1 HR P20171889 T1 HRP20171889 T1 HR P20171889T1 HR P20171889T T HRP20171889T T HR P20171889TT HR P20171889 T HRP20171889 T HR P20171889T HR P20171889 T1 HRP20171889 T1 HR P20171889T1
Authority
HR
Croatia
Prior art keywords
darunavir
combination formulations
formulations
combination
darunavir combination
Prior art date
Application number
HRP20171889TT
Other languages
English (en)
Inventor
Urbain Alfons C DELAET
Philip Erna H HEYNS
Eugeen Maria Jozef Jans
Roel Jos M. Mertens
Geert VAN DER AVOORT
Original Assignee
Janssen Sciences Ireland Uc
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc, Gilead Sciences, Inc. filed Critical Janssen Sciences Ireland Uc
Publication of HRP20171889T1 publication Critical patent/HRP20171889T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
HRP20171889TT 2011-07-07 2017-12-05 Formulacije kombinacije darunavira HRP20171889T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11173067 2011-07-07
PCT/EP2012/063249 WO2013004818A1 (en) 2011-07-07 2012-07-06 Darunavir combination formulations
EP12738060.8A EP2729130B1 (en) 2011-07-07 2012-07-06 Darunavir combination formulations

Publications (1)

Publication Number Publication Date
HRP20171889T1 true HRP20171889T1 (hr) 2018-01-12

Family

ID=46551505

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171889TT HRP20171889T1 (hr) 2011-07-07 2017-12-05 Formulacije kombinacije darunavira

Country Status (23)

Country Link
US (3) US20140142070A1 (hr)
EP (1) EP2729130B1 (hr)
JP (1) JP6122427B2 (hr)
KR (1) KR102058097B1 (hr)
CN (1) CN103826616B (hr)
AU (1) AU2012280198B2 (hr)
BR (1) BR112014000290B1 (hr)
CA (1) CA2838659C (hr)
CY (1) CY1121999T1 (hr)
DK (1) DK2729130T3 (hr)
EA (1) EA026587B1 (hr)
ES (1) ES2651212T3 (hr)
HR (1) HRP20171889T1 (hr)
HU (1) HUE035241T2 (hr)
IL (1) IL229933A (hr)
LT (1) LT2729130T (hr)
MX (1) MX343689B (hr)
NO (1) NO2729130T3 (hr)
PL (1) PL2729130T3 (hr)
PT (1) PT2729130T (hr)
RS (1) RS56667B1 (hr)
SI (1) SI2729130T1 (hr)
WO (1) WO2013004818A1 (hr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE035241T2 (en) 2011-07-07 2018-05-02 Janssen Sciences Ireland Uc Darunavir combination products
WO2013130766A1 (en) * 2012-03-01 2013-09-06 Gilead Sciences, Inc. Spray dried formulations
CA3012242C (en) 2012-12-21 2021-11-02 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
EP3632415A1 (en) 2015-11-09 2020-04-08 Gilead Sciences, Inc. Therapeutic compositions for treatment of human immunodeficiency virus
US20190175509A1 (en) * 2016-08-08 2019-06-13 Hetero Labs Limited High Drug Loaded Tablet Composition for Treating HIV
EP3496719B1 (en) * 2016-08-08 2023-06-14 Hetero Labs Limited A multi-class anti-retroviral composition
WO2018029561A1 (en) 2016-08-08 2018-02-15 Hetero Labs Limited Anti-retroviral compositions
US20180085387A1 (en) * 2016-09-27 2018-03-29 Gilead Sciences, Inc. Therapeutic compositions for treatment of human immunodeficiency virus
US10786518B2 (en) * 2017-07-20 2020-09-29 Janssen Sciences Ireland Uc Compositions and methods of treating HIV
US20200101093A1 (en) 2018-09-28 2020-04-02 Janssen Sciences Ireland Unlimited Company Methods of Treating and Preventing Neuropsychiatric and/or Neurocognitive Complications in Patients Infected with HIV
WO2021180963A1 (en) 2020-03-13 2021-09-16 Janssen Sciences Ireland Unlimited Company A protease inhibitor regimen for treating subjects infected with hiv

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US5968942A (en) 1992-08-25 1999-10-19 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
ES2127938T3 (es) 1993-08-24 1999-05-01 Searle & Co Hidroxietilamino sulfonamidas utiles como inhibidores de proteasas retroviricas.
AU771780B2 (en) 1998-06-23 2004-04-01 Board Of Trustees Of The University Of Illinois, The Fitness assay and associated methods
TWI286476B (en) 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
HUE034389T2 (en) 2002-05-16 2018-02-28 Janssen Sciences Ireland Uc Pseudopolymorphic forms of an HIV protease inhibitor
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
WO2007143422A2 (en) 2006-05-30 2007-12-13 Janssen Pharmaceutica N.V. Substituted pyridyl amide compounds as modulators of the histamine h3 receptor
US20080039428A1 (en) * 2006-06-29 2008-02-14 Panacos Pharmaceuticals, Inc. Antiretroviral combination therapy
TWI411613B (zh) 2006-07-07 2013-10-11 Gilead Sciences Inc 用於改善被細胞色素p450單氧合酶所代謝之治療劑的藥物動力性質之調節劑
MX2009004439A (es) * 2006-10-25 2009-05-11 Mcneil Ppc Inc Composicion de ibuprofeno.
MX2009008935A (es) 2007-02-23 2009-11-02 Gilead Sciences Inc Moduladores de las propiedades farmacocineticas de productos terapeuticos.
US20100190809A1 (en) 2007-06-25 2010-07-29 Jody Firmin Voorspoels Combination formulations
AR069539A1 (es) 2007-07-25 2010-02-03 Tibotec Pharm Ltd Avances respecto de las formulaciones de comprimidos contra el vih
NZ584998A (en) 2007-11-20 2012-08-31 Janssen Pharmaceutica Nv Cycloalkyloxy-and heterocycloalkyloxypyridine compounds as modulators of the histamine h3 receptor
GT200800303A (es) * 2007-12-24 2009-09-18 Combinacion anti-retroviral
EA201591353A1 (ru) * 2008-05-02 2016-01-29 Джилид Сайэнс, Инк. Применение частиц твердого носителя для улучшения технологических характеристик фармацевтического агента
PE20110994A1 (es) * 2009-02-06 2012-01-24 Gilead Sciences Inc Comprimidos antivirales que comprenden elvitegravir, emtricitabina, disoproxil fumarato de tenofovir y un derivado de tiazol
CA2776807C (en) * 2009-09-17 2018-10-16 Mylan Laboratories Limited An improved process for the preparation of darunavir
WO2011141921A1 (en) 2010-05-10 2011-11-17 Hetero Research Foundation Darunavir compositions
HUE035241T2 (en) 2011-07-07 2018-05-02 Janssen Sciences Ireland Uc Darunavir combination products
BR112014000195A2 (pt) 2011-07-07 2017-02-21 Janssen R&D Ireland formulações de darunavir
WO2013115916A1 (en) 2012-02-03 2013-08-08 Gilead Sciences, Inc. Combination therapy comprising gs-7340 and cobicistat for use in the treatment of viral infections
JP2018502118A (ja) 2015-01-03 2018-01-25 マイラン・ラボラトリーズ・リミテッドMylan Laboratories Limited 非晶質ヘミフマル酸テノホビルアラフェナミドおよびその予備混合物を調製するプロセス

Also Published As

Publication number Publication date
BR112014000290A2 (pt) 2017-02-07
EA201490222A1 (ru) 2014-04-30
CN103826616B (zh) 2016-08-10
WO2013004818A1 (en) 2013-01-10
PT2729130T (pt) 2017-12-13
US20230302024A1 (en) 2023-09-28
AU2012280198A1 (en) 2014-01-09
KR102058097B1 (ko) 2019-12-20
MX343689B (es) 2016-11-16
CY1121999T1 (el) 2020-07-31
AU2012280198B2 (en) 2016-12-22
BR112014000290B1 (pt) 2022-05-10
CA2838659A1 (en) 2013-01-10
NO2729130T3 (hr) 2018-02-03
KR20140068845A (ko) 2014-06-09
US11654150B2 (en) 2023-05-23
RS56667B1 (sr) 2018-03-30
EP2729130B1 (en) 2017-09-06
PL2729130T3 (pl) 2018-02-28
SI2729130T1 (en) 2018-03-30
JP2014520787A (ja) 2014-08-25
CA2838659C (en) 2020-02-18
HUE035241T2 (en) 2018-05-02
JP6122427B2 (ja) 2017-04-26
ES2651212T3 (es) 2018-01-25
AU2012280198A8 (en) 2014-01-16
IL229933A (en) 2017-09-28
EA026587B1 (ru) 2017-04-28
CN103826616A (zh) 2014-05-28
EP2729130A1 (en) 2014-05-14
US20200093840A1 (en) 2020-03-26
US20140142070A1 (en) 2014-05-22
MX2013015199A (es) 2014-09-01
DK2729130T3 (en) 2017-12-11
LT2729130T (lt) 2018-01-10

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