ZW6284A1 - Novel pyrimidone derivatives - Google Patents

Novel pyrimidone derivatives

Info

Publication number
ZW6284A1
ZW6284A1 ZW62/84A ZW6284A ZW6284A1 ZW 6284 A1 ZW6284 A1 ZW 6284A1 ZW 62/84 A ZW62/84 A ZW 62/84A ZW 6284 A ZW6284 A ZW 6284A ZW 6284 A1 ZW6284 A1 ZW 6284A1
Authority
ZW
Zimbabwe
Prior art keywords
pyrimidone derivatives
novel pyrimidone
novel
derivatives
pyrimidone
Prior art date
Application number
ZW62/84A
Other languages
English (en)
Inventor
Kaiser Ado
Kienzle Frank
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZW6284A1 publication Critical patent/ZW6284A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/62Barbituric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZW62/84A 1983-05-05 1984-04-13 Novel pyrimidone derivatives ZW6284A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH244283 1983-05-05
CH139284 1984-03-20

Publications (1)

Publication Number Publication Date
ZW6284A1 true ZW6284A1 (en) 1985-10-30

Family

ID=25687524

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW62/84A ZW6284A1 (en) 1983-05-05 1984-04-13 Novel pyrimidone derivatives

Country Status (16)

Country Link
US (1) US4581172A (xx)
EP (1) EP0124893A3 (xx)
AU (1) AU2751084A (xx)
CA (1) CA1237429A (xx)
CS (1) CS243486B2 (xx)
DK (1) DK198784A (xx)
ES (1) ES8505369A1 (xx)
FI (1) FI841619A (xx)
HU (1) HUT34025A (xx)
IL (1) IL71711A (xx)
MC (1) MC1600A1 (xx)
NO (1) NO841780L (xx)
NZ (1) NZ207981A (xx)
PH (1) PH19219A (xx)
PT (1) PT78549B (xx)
ZW (1) ZW6284A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134984B1 (en) * 1983-07-16 1988-07-13 Beecham Group Plc Benzazepine and benzoxazepine derivatives
GB9707251D0 (en) * 1997-04-10 1997-05-28 Smithkline Beecham Plc Novel method and compounds
DE60005493T2 (de) * 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido[6,1-a]isochinolinonderivate
US7169907B2 (en) * 2002-03-01 2007-01-30 Roche Diagnostics Operations, Inc. Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs
JP2007525475A (ja) * 2003-07-08 2007-09-06 スミスクライン・ビーチャム・コーポレイション 新規化学化合物
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
WO2017016960A1 (en) * 2015-07-24 2017-02-02 F. Hoffmann-La Roche Ag Process for the preparation of (6s)-6-alkyl-10-alkoxy-9-(substituted alkoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid analogues
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process
AU2019302610B2 (en) 2018-07-13 2023-11-23 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Fused tri-cyclic compound as PDE3/PDE4 dual inhibitor
US20230060174A1 (en) * 2020-01-15 2023-03-02 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Pharmaceutical composition of tricyclic pde3/pde4 dual inhibitor compound
JP2023512471A (ja) * 2020-01-15 2023-03-27 チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド Pde3/pde4二重阻害剤の結晶及びその使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ185900A (en) * 1976-12-10 1981-04-24 Hoechst Ag Pyrimido (6,1-a) isoquinolin-4-ones medicaments intermediate isoquinolines
DE2720085A1 (de) * 1977-05-05 1978-11-16 Hoechst Ag Pyrimido(6,1-a)isochinolin-2-on- derivate
FI64370C (fi) * 1977-05-05 1983-11-10 Hoechst Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat
DE2847693A1 (de) * 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
DE3135831A1 (de) * 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0124893A2 (de) 1984-11-14
US4581172A (en) 1986-04-08
HUT34025A (en) 1985-01-28
FI841619A (fi) 1984-11-06
AU2751084A (en) 1984-11-08
NZ207981A (en) 1987-05-29
PH19219A (en) 1986-02-12
MC1600A1 (fr) 1985-05-09
DK198784A (da) 1984-11-06
EP0124893A3 (de) 1987-11-11
CS243486B2 (en) 1986-06-12
FI841619A0 (fi) 1984-04-25
CS325584A2 (en) 1985-08-15
PT78549A (en) 1984-06-01
NO841780L (no) 1984-11-06
ES532172A0 (es) 1985-06-01
CA1237429A (en) 1988-05-31
DK198784D0 (da) 1984-04-17
PT78549B (en) 1986-09-15
IL71711A (en) 1987-08-31
ES8505369A1 (es) 1985-06-01
IL71711A0 (en) 1984-09-30

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