ZW15181A1 - Novel cephalosporins with improved anti-bacterial and pharmaco kinetic properties - Google Patents

Novel cephalosporins with improved anti-bacterial and pharmaco kinetic properties

Info

Publication number
ZW15181A1
ZW15181A1 ZW151/81A ZW15181A ZW15181A1 ZW 15181 A1 ZW15181 A1 ZW 15181A1 ZW 151/81 A ZW151/81 A ZW 151/81A ZW 15181 A ZW15181 A ZW 15181A ZW 15181 A1 ZW15181 A1 ZW 15181A1
Authority
ZW
Zimbabwe
Prior art keywords
bacterial
improved anti
kinetic properties
novel cephalosporins
pharmaco kinetic
Prior art date
Application number
ZW151/81A
Other languages
English (en)
Inventor
David Alan Berges
George Lawrence Dunn
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of ZW15181A1 publication Critical patent/ZW15181A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZW151/81A 1980-07-03 1981-07-01 Novel cephalosporins with improved anti-bacterial and pharmaco kinetic properties ZW15181A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/165,822 US4308267A (en) 1980-07-03 1980-07-03 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins

Publications (1)

Publication Number Publication Date
ZW15181A1 true ZW15181A1 (en) 1981-09-29

Family

ID=22600626

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW151/81A ZW15181A1 (en) 1980-07-03 1981-07-01 Novel cephalosporins with improved anti-bacterial and pharmaco kinetic properties

Country Status (23)

Country Link
US (1) US4308267A (es)
EP (1) EP0043713B1 (es)
JP (1) JPS5745189A (es)
KR (1) KR840002046B1 (es)
AR (1) AR228606A1 (es)
AT (1) ATE9585T1 (es)
AU (1) AU547942B2 (es)
CA (1) CA1151150A (es)
DE (1) DE3166321D1 (es)
DK (1) DK286981A (es)
ES (1) ES8203908A1 (es)
FI (1) FI66876C (es)
GR (1) GR74363B (es)
HU (1) HU185934B (es)
IE (1) IE51365B1 (es)
IL (1) IL63206A (es)
NO (1) NO812268L (es)
NZ (1) NZ197573A (es)
PH (1) PH17670A (es)
PT (1) PT73292B (es)
YU (1) YU162481A (es)
ZA (1) ZA814484B (es)
ZW (1) ZW15181A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526977A (en) * 1981-10-07 1985-07-02 American Home Products Corporation 2-(3-Amino-5-isoxazolyl)-2-oxyimino-acetic acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS52125188A (en) 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
DE2714880A1 (de) 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
MC1259A1 (fr) 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
US4220761A (en) * 1978-09-12 1980-09-02 Fujisawa Pharmaceutical Co., Ltd. 7-[Substituted oximinoacetamido]-3-[hydroxy alkyltetrazolo]cephalosporin derivatives

Also Published As

Publication number Publication date
AR228606A1 (es) 1983-03-30
EP0043713A1 (en) 1982-01-13
FI66876C (fi) 1984-12-10
GR74363B (es) 1984-06-28
HU185934B (en) 1985-04-28
ZA814484B (en) 1982-07-28
YU162481A (en) 1983-06-30
AU547942B2 (en) 1985-11-14
EP0043713B1 (en) 1984-09-26
KR830006310A (ko) 1983-09-20
ATE9585T1 (de) 1984-10-15
AU7234381A (en) 1982-01-07
ES503622A0 (es) 1982-04-01
DE3166321D1 (en) 1984-10-31
IE811481L (en) 1982-01-03
CA1151150A (en) 1983-08-02
JPS5745189A (en) 1982-03-13
PT73292B (en) 1982-07-22
PT73292A (en) 1981-07-01
US4308267A (en) 1981-12-29
IL63206A (en) 1986-09-30
IE51365B1 (en) 1986-12-10
DK286981A (da) 1982-01-04
ES8203908A1 (es) 1982-04-01
KR840002046B1 (ko) 1984-11-06
FI66876B (fi) 1984-08-31
IL63206A0 (en) 1981-09-13
FI812046L (fi) 1982-01-04
PH17670A (en) 1984-11-02
NO812268L (no) 1982-01-04
NZ197573A (en) 1984-09-28

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