ZA988095B - New peptide mimetics for the treatment of bone metabolic disorders, methods for their production, and drugs containing these compounds. - Google Patents
New peptide mimetics for the treatment of bone metabolic disorders, methods for their production, and drugs containing these compounds.Info
- Publication number
- ZA988095B ZA988095B ZA9808095A ZA988095A ZA988095B ZA 988095 B ZA988095 B ZA 988095B ZA 9808095 A ZA9808095 A ZA 9808095A ZA 988095 A ZA988095 A ZA 988095A ZA 988095 B ZA988095 B ZA 988095B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- treatment
- production
- methods
- metabolic disorders
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 208000030159 metabolic disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97115402A EP0902036A1 (en) | 1997-09-05 | 1997-09-05 | Peptide containing an arginine mimetic for the treatment of osteoporosis, their production, and drugs containing these compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA988095B true ZA988095B (en) | 2000-03-22 |
Family
ID=8227319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9808095A ZA988095B (en) | 1997-09-05 | 1998-09-04 | New peptide mimetics for the treatment of bone metabolic disorders, methods for their production, and drugs containing these compounds. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6429288B1 (zh) |
| EP (2) | EP0902036A1 (zh) |
| JP (1) | JP2001515919A (zh) |
| KR (1) | KR20010023656A (zh) |
| CN (1) | CN1269806A (zh) |
| AR (1) | AR013462A1 (zh) |
| AU (1) | AU9439398A (zh) |
| BR (1) | BR9812056A (zh) |
| CA (1) | CA2301969A1 (zh) |
| TR (1) | TR200000598T2 (zh) |
| WO (1) | WO1999012970A1 (zh) |
| ZA (1) | ZA988095B (zh) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0115079A (pt) * | 2000-10-30 | 2003-08-19 | Warner Lambert Co | Ligandos do receptor de serotonina à base de amidino-uréia e composições destes, seus usos farmacêuticos e métodos para a suas sìnteses |
| US6946562B2 (en) * | 2001-12-12 | 2005-09-20 | Eastman Kodak Company | Synthesis of peptoid substituted azole compounds |
| US8768642B2 (en) | 2003-09-15 | 2014-07-01 | Nvidia Corporation | System and method for remotely configuring semiconductor functional circuits |
| US8775997B2 (en) | 2003-09-15 | 2014-07-08 | Nvidia Corporation | System and method for testing and configuring semiconductor functional circuits |
| US8732644B1 (en) | 2003-09-15 | 2014-05-20 | Nvidia Corporation | Micro electro mechanical switch system and method for testing and configuring semiconductor functional circuits |
| US8711161B1 (en) | 2003-12-18 | 2014-04-29 | Nvidia Corporation | Functional component compensation reconfiguration system and method |
| US8723231B1 (en) | 2004-09-15 | 2014-05-13 | Nvidia Corporation | Semiconductor die micro electro-mechanical switch management system and method |
| US8711156B1 (en) | 2004-09-30 | 2014-04-29 | Nvidia Corporation | Method and system for remapping processing elements in a pipeline of a graphics processing unit |
| US8021193B1 (en) | 2005-04-25 | 2011-09-20 | Nvidia Corporation | Controlled impedance display adapter |
| US7793029B1 (en) | 2005-05-17 | 2010-09-07 | Nvidia Corporation | Translation device apparatus for configuring printed circuit board connectors |
| US8412872B1 (en) | 2005-12-12 | 2013-04-02 | Nvidia Corporation | Configurable GPU and method for graphics processing using a configurable GPU |
| US8417838B2 (en) * | 2005-12-12 | 2013-04-09 | Nvidia Corporation | System and method for configurable digital communication |
| US8724483B2 (en) | 2007-10-22 | 2014-05-13 | Nvidia Corporation | Loopback configuration for bi-directional interfaces |
| US8687639B2 (en) * | 2009-06-04 | 2014-04-01 | Nvidia Corporation | Method and system for ordering posted packets and non-posted packets transfer |
| US9176909B2 (en) | 2009-12-11 | 2015-11-03 | Nvidia Corporation | Aggregating unoccupied PCI-e links to provide greater bandwidth |
| US9331869B2 (en) * | 2010-03-04 | 2016-05-03 | Nvidia Corporation | Input/output request packet handling techniques by a device specific kernel mode driver |
| US9330031B2 (en) | 2011-12-09 | 2016-05-03 | Nvidia Corporation | System and method for calibration of serial links using a serial-to-parallel loopback |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5645591A (en) | 1990-05-29 | 1997-07-08 | Stryker Corporation | Synthetic bone matrix |
| ES2135398T3 (es) * | 1990-12-13 | 1999-11-01 | Univ Melbourne | Compuesto y composiciones de inhibicion de la resorcion osea. |
| CA2111199C (en) | 1991-06-21 | 2008-08-05 | Eyal Ron | Pharmaceutical formulations of osteogenic proteins |
| WO1993020859A1 (en) | 1992-04-20 | 1993-10-28 | Board Of Regents Of The University Of Washington | Sustained release compositions for delivery of growth factors |
| CA2093836A1 (en) | 1992-04-24 | 1993-10-25 | Wayne Gombotz | Biodegradable tgf-.beta. delivery system for bone regeneration |
| CA2119090A1 (en) | 1993-03-26 | 1994-09-27 | Wayne R. Gombotz | Compositions for controlled release of biologically active tgf-.beta. |
| HUT72734A (en) | 1993-04-08 | 1996-05-28 | Ciba Geigy Ag | Proces for producing bone-resorption-inhibiting cyclic compounds and compositions |
| ATE236192T1 (de) * | 1995-12-09 | 2003-04-15 | Akzo Nobel Nv | 3-aminoethyl-n-amidino-2,5-dihydropyrrol derivative mit arginine-mimetischen eigenschaften |
-
1997
- 1997-09-05 EP EP97115402A patent/EP0902036A1/en not_active Withdrawn
-
1998
- 1998-09-02 KR KR1020007002308A patent/KR20010023656A/ko not_active Application Discontinuation
- 1998-09-02 US US09/486,679 patent/US6429288B1/en not_active Expired - Fee Related
- 1998-09-02 AU AU94393/98A patent/AU9439398A/en not_active Abandoned
- 1998-09-02 BR BR9812056-5A patent/BR9812056A/pt not_active IP Right Cessation
- 1998-09-02 TR TR2000/00598T patent/TR200000598T2/xx unknown
- 1998-09-02 EP EP98947498A patent/EP1009770A1/en not_active Withdrawn
- 1998-09-02 CA CA002301969A patent/CA2301969A1/en not_active Abandoned
- 1998-09-02 CN CN98808822A patent/CN1269806A/zh active Pending
- 1998-09-02 WO PCT/EP1998/005547 patent/WO1999012970A1/en not_active Application Discontinuation
- 1998-09-02 JP JP2000510775A patent/JP2001515919A/ja active Pending
- 1998-09-03 AR ARP980104401A patent/AR013462A1/es unknown
- 1998-09-04 ZA ZA9808095A patent/ZA988095B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010023656A (ko) | 2001-03-26 |
| AR013462A1 (es) | 2000-12-27 |
| BR9812056A (pt) | 2000-09-26 |
| JP2001515919A (ja) | 2001-09-25 |
| EP1009770A1 (en) | 2000-06-21 |
| CA2301969A1 (en) | 1999-03-18 |
| EP0902036A1 (en) | 1999-03-17 |
| CN1269806A (zh) | 2000-10-11 |
| AU9439398A (en) | 1999-03-29 |
| TR200000598T2 (tr) | 2000-07-21 |
| WO1999012970A1 (en) | 1999-03-18 |
| US6429288B1 (en) | 2002-08-06 |
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