ZA982969B - 1,2,3,4-tetrahydro-benzofuro[3,2-c]pyridine derivatives. - Google Patents

1,2,3,4-tetrahydro-benzofuro[3,2-c]pyridine derivatives.

Info

Publication number
ZA982969B
ZA982969B ZA9802969A ZA982969A ZA982969B ZA 982969 B ZA982969 B ZA 982969B ZA 9802969 A ZA9802969 A ZA 9802969A ZA 982969 A ZA982969 A ZA 982969A ZA 982969 B ZA982969 B ZA 982969B
Authority
ZA
South Africa
Prior art keywords
benzofuro
tetrahydro
pyridine derivatives
pyridine
derivatives
Prior art date
Application number
ZA9802969A
Other languages
English (en)
Inventor
Ludo Edmond Josephina Kennis
Christopher John Love
Francois Paul Bischoff
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA982969B publication Critical patent/ZA982969B/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA9802969A 1997-04-08 1998-04-07 1,2,3,4-tetrahydro-benzofuro[3,2-c]pyridine derivatives. ZA982969B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201045 1997-04-08

Publications (1)

Publication Number Publication Date
ZA982969B true ZA982969B (en) 1999-10-07

Family

ID=8228191

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9802969A ZA982969B (en) 1997-04-08 1998-04-07 1,2,3,4-tetrahydro-benzofuro[3,2-c]pyridine derivatives.

Country Status (31)

Country Link
US (1) US6156757A (cs)
EP (1) EP1019408B1 (cs)
JP (1) JP3287577B2 (cs)
KR (1) KR100315975B1 (cs)
CN (1) CN1097053C (cs)
AP (1) AP1138A (cs)
AR (1) AR012576A1 (cs)
AT (1) ATE270294T1 (cs)
AU (1) AU727599B2 (cs)
BG (1) BG63848B1 (cs)
BR (1) BR9806263A (cs)
CA (1) CA2264598C (cs)
CZ (1) CZ290008B6 (cs)
DE (1) DE69824872T2 (cs)
EE (1) EE03691B1 (cs)
ES (1) ES2224391T3 (cs)
GE (1) GEP20022823B (cs)
HU (1) HUP0003624A3 (cs)
ID (1) ID22131A (cs)
IL (1) IL128701A0 (cs)
MY (1) MY120033A (cs)
NO (1) NO322826B1 (cs)
NZ (1) NZ334501A (cs)
PL (1) PL189549B1 (cs)
RU (1) RU2198175C2 (cs)
SK (1) SK283621B6 (cs)
TR (1) TR199900644T2 (cs)
TW (1) TW589315B (cs)
UA (1) UA52681C2 (cs)
WO (1) WO1998045297A1 (cs)
ZA (1) ZA982969B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA52681C2 (uk) * 1997-04-08 2003-01-15 Янссен Фармацевтика Н.В. Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі
UA70334C2 (en) * 1998-10-06 2004-10-15 Janssen Pharmaceutica N V Jans BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS
RU2226194C2 (ru) * 1998-10-06 2004-03-27 Янссен Фармацевтика Н.В. Трициклические δ3-пиперидины, способы их получения и фармацевтическая композиция на их основе
HUP0104812A3 (en) * 1998-12-21 2003-12-29 Janssen Pharmaceutica Nv Benzisoxazoles and phenones as alpha2-antagonists, process for their preparation and medicaments containing them
WO2003004501A2 (en) * 2001-07-05 2003-01-16 Pharmacia & Upjohn Company (hetero) aryl substituted benzofurans as 5-ht ligands
JP2005521728A (ja) * 2002-04-03 2005-07-21 オリオン コーポレーション ＣＮＳ関連疾患のためのα２−アドレナリン受容体アンタゴニストの使用
ES2440217T3 (es) * 2002-10-04 2014-01-28 Prana Biotechnology Limited Compuestos neurológicamente activos
BRPI0509893A (pt) 2004-04-12 2007-10-30 Taisho Pharmaceutical Co Ltd composto de amina cìclica
RU2409582C2 (ru) * 2004-08-31 2011-01-20 Глэксо Груп Лимитед Конденсированные трициклические производные для лечения психотических расстройств
WO2008050732A1 (fr) * 2006-10-23 2008-05-02 Takeda Pharmaceutical Company Limited Dérivé de l'iminopyridine et son utilisation
US20110039846A1 (en) * 2008-04-23 2011-02-17 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof
US8481569B2 (en) * 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof
WO2011044134A1 (en) * 2009-10-05 2011-04-14 Albany Molecular Research, Inc. Epiminocycloalkyl(b)indole derivatives as serotonin sub-type 6 (5-ht6) modulators and uses thereof
WO2012099952A2 (en) * 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
GB201704325D0 (en) * 2017-03-17 2017-05-03 Argonaut Therapeutics Ltd Compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4688803A (en) * 1984-06-25 1987-08-25 Ollington Robert F Casino game table and dice
FR2570701B1 (fr) * 1984-09-27 1987-05-22 Synthelabo Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique
US4686226A (en) * 1985-09-03 1987-08-11 Merck & Co., Inc. Substituted benzo[b]furo- and benzo[b]thieno quinolizines
RU2045529C1 (ru) * 1988-04-26 1995-10-10 Ниссан Кемикал Индастриз Лтд. Способ получения мевалонолактоновых производных
US4985422A (en) * 1988-04-27 1991-01-15 Glaxo Group Limited Lactam derivatives
DE4308451A1 (de) * 1992-09-10 1994-04-14 Bayer Ag 3-Aryl-pyron-Derivate
UA52681C2 (uk) * 1997-04-08 2003-01-15 Янссен Фармацевтика Н.В. Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі

Also Published As

Publication number Publication date
EP1019408B1 (en) 2004-06-30
PL332382A1 (en) 1999-09-13
GEP20022823B (en) 2002-10-25
HUP0003624A2 (hu) 2001-04-28
DE69824872T2 (de) 2005-09-01
ID22131A (id) 1999-09-09
CZ68299A3 (cs) 2000-08-16
AR012576A1 (es) 2000-11-08
BG103213A (en) 2000-05-31
KR20000036076A (ko) 2000-06-26
AU727599B2 (en) 2000-12-14
US6156757A (en) 2000-12-05
AP9901650A0 (en) 1999-09-30
UA52681C2 (uk) 2003-01-15
JP3287577B2 (ja) 2002-06-04
MY120033A (en) 2005-08-30
IL128701A0 (en) 2000-01-31
SK28799A3 (en) 2001-03-12
CN1237179A (zh) 1999-12-01
NO322826B1 (no) 2006-12-11
CA2264598A1 (en) 1998-10-15
JP2000505115A (ja) 2000-04-25
RU2198175C2 (ru) 2003-02-10
ATE270294T1 (de) 2004-07-15
DE69824872D1 (de) 2004-08-05
BG63848B1 (bg) 2003-03-31
EP1019408A1 (en) 2000-07-19
SK283621B6 (sk) 2003-10-07
NO990859D0 (no) 1999-02-23
HUP0003624A3 (en) 2002-09-30
CZ290008B6 (cs) 2002-05-15
AP1138A (en) 2003-01-17
CA2264598C (en) 2006-10-24
ES2224391T3 (es) 2005-03-01
KR100315975B1 (ko) 2001-12-22
EE03691B1 (et) 2002-04-15
EE9900114A (et) 1999-12-15
WO1998045297A1 (en) 1998-10-15
NZ334501A (en) 2000-06-23
BR9806263A (pt) 2000-04-04
TW589315B (en) 2004-06-01
AU7430798A (en) 1998-10-30
NO990859L (no) 1999-09-30
TR199900644T2 (xx) 2000-09-21
PL189549B1 (pl) 2005-08-31
CN1097053C (zh) 2002-12-25

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