EE9900114A - 1,2,3,4-tetrahüdrobensofuro[3,4-c]püridiini derivaadid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetod - Google Patents
1,2,3,4-tetrahüdrobensofuro[3,4-c]püridiini derivaadid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetodInfo
- Publication number
- EE9900114A EE9900114A EEP199900114A EEP9900114A EE9900114A EE 9900114 A EE9900114 A EE 9900114A EE P199900114 A EEP199900114 A EE P199900114A EE P9900114 A EEP9900114 A EE P9900114A EE 9900114 A EE9900114 A EE 9900114A
- Authority
- EE
- Estonia
- Prior art keywords
- preparation
- tetrahydrobenzofuro
- pharmaceutical composition
- pyridine derivatives
- pyridine
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- BFJMHTOBRRZELQ-UHFFFAOYSA-N 3-iodo-2h-pyrazolo[3,4-c]pyridine Chemical class N1=CC=C2C(I)=NNC2=C1 BFJMHTOBRRZELQ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97201045 | 1997-04-08 | ||
PCT/EP1998/002136 WO1998045297A1 (en) | 1997-04-08 | 1998-04-02 | 1,2,3,4-TETRAHYDRO-BENZOFURO[3,2-c]PYRIDINE DERIVATIVES__ |
Publications (2)
Publication Number | Publication Date |
---|---|
EE9900114A true EE9900114A (et) | 1999-12-15 |
EE03691B1 EE03691B1 (et) | 2002-04-15 |
Family
ID=8228191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP199900114A EE03691B1 (et) | 1997-04-08 | 1998-04-02 | 1,2,3,4-tetrahüdrobensofuro[3,4-c]püridiini derivaadid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetod |
Country Status (31)
Country | Link |
---|---|
US (1) | US6156757A (et) |
EP (1) | EP1019408B1 (et) |
JP (1) | JP3287577B2 (et) |
KR (1) | KR100315975B1 (et) |
CN (1) | CN1097053C (et) |
AP (1) | AP1138A (et) |
AR (1) | AR012576A1 (et) |
AT (1) | ATE270294T1 (et) |
AU (1) | AU727599B2 (et) |
BG (1) | BG63848B1 (et) |
BR (1) | BR9806263A (et) |
CA (1) | CA2264598C (et) |
CZ (1) | CZ290008B6 (et) |
DE (1) | DE69824872T2 (et) |
EE (1) | EE03691B1 (et) |
ES (1) | ES2224391T3 (et) |
GE (1) | GEP20022823B (et) |
HU (1) | HUP0003624A3 (et) |
ID (1) | ID22131A (et) |
IL (1) | IL128701A0 (et) |
MY (1) | MY120033A (et) |
NO (1) | NO322826B1 (et) |
NZ (1) | NZ334501A (et) |
PL (1) | PL189549B1 (et) |
RU (1) | RU2198175C2 (et) |
SK (1) | SK283621B6 (et) |
TR (1) | TR199900644T2 (et) |
TW (1) | TW589315B (et) |
UA (1) | UA52681C2 (et) |
WO (1) | WO1998045297A1 (et) |
ZA (1) | ZA982969B (et) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA52681C2 (uk) * | 1997-04-08 | 2003-01-15 | Янссен Фармацевтика Н.В. | Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі |
DE69918148T2 (de) * | 1998-10-06 | 2005-07-28 | Janssen Pharmaceutica N.V. | Trizyclische delta3-pyridine als arzneimittel |
UA70334C2 (en) * | 1998-10-06 | 2004-10-15 | Janssen Pharmaceutica N V Jans | BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS |
CA2355716C (en) * | 1998-12-21 | 2010-05-18 | Janssen Pharmaceutica N.V. | Benzisoxazoles and phenones as .alpha.2-antagonists |
MXPA04000036A (es) | 2001-07-05 | 2004-05-21 | Upjohn Co | Benzofuranos sustituidos con (hetero) arilo como ligandos 5-ht. |
JP2005521728A (ja) * | 2002-04-03 | 2005-07-21 | オリオン コーポレーション | CNS関連疾患のためのα2−アドレナリン受容体アンタゴニストの使用 |
EP2210892A3 (en) * | 2002-10-04 | 2010-10-27 | Prana Biotechnology Limited | Neurologically-active compounds |
KR20060135023A (ko) * | 2004-04-12 | 2006-12-28 | 다이쇼 세이야꾸 가부시끼가이샤 | 환상 아민 화합물 |
JP5483880B2 (ja) * | 2006-10-23 | 2014-05-07 | 武田薬品工業株式会社 | イミノピリジン誘導体およびその用途 |
US8481569B2 (en) * | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
US20090270393A1 (en) * | 2008-04-23 | 2009-10-29 | Takeda Pharmaceutical Company Limited | Iminopyridine Derivatives and Use Thereof |
US8575186B2 (en) * | 2009-10-05 | 2013-11-05 | Albany Molecular Research, Inc. | Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof |
CA2823955A1 (en) | 2011-01-19 | 2012-07-26 | Albany Molecular Research, Inc. | Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia |
GB201704325D0 (en) * | 2017-03-17 | 2017-05-03 | Argonaut Therapeutics Ltd | Compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2570701B1 (fr) * | 1984-09-27 | 1987-05-22 | Synthelabo | Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique |
US4686226A (en) * | 1985-09-03 | 1987-08-11 | Merck & Co., Inc. | Substituted benzo[b]furo- and benzo[b]thieno quinolizines |
EP0339959A3 (en) * | 1988-04-27 | 1991-03-20 | Glaxo Group Limited | Lactam derivatives |
UA52681C2 (uk) * | 1997-04-08 | 2003-01-15 | Янссен Фармацевтика Н.В. | Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі |
-
1998
- 1998-02-04 UA UA99031180A patent/UA52681C2/uk unknown
- 1998-04-02 CN CN98801286A patent/CN1097053C/zh not_active Expired - Lifetime
- 1998-04-02 ID IDW990147D patent/ID22131A/id unknown
- 1998-04-02 ES ES98921458T patent/ES2224391T3/es not_active Expired - Lifetime
- 1998-04-02 BR BR9806263-8A patent/BR9806263A/pt not_active Application Discontinuation
- 1998-04-02 JP JP54240698A patent/JP3287577B2/ja not_active Expired - Fee Related
- 1998-04-02 WO PCT/EP1998/002136 patent/WO1998045297A1/en active IP Right Grant
- 1998-04-02 PL PL98332382A patent/PL189549B1/pl unknown
- 1998-04-02 RU RU99107290/04A patent/RU2198175C2/ru active
- 1998-04-02 CA CA002264598A patent/CA2264598C/en not_active Expired - Lifetime
- 1998-04-02 KR KR1019997002086A patent/KR100315975B1/ko not_active IP Right Cessation
- 1998-04-02 IL IL12870198A patent/IL128701A0/xx not_active IP Right Cessation
- 1998-04-02 NZ NZ334501A patent/NZ334501A/en unknown
- 1998-04-02 CZ CZ1999682A patent/CZ290008B6/cs not_active IP Right Cessation
- 1998-04-02 AU AU74307/98A patent/AU727599B2/en not_active Expired
- 1998-04-02 AT AT98921458T patent/ATE270294T1/de not_active IP Right Cessation
- 1998-04-02 US US09/402,593 patent/US6156757A/en not_active Expired - Lifetime
- 1998-04-02 EP EP98921458A patent/EP1019408B1/en not_active Expired - Lifetime
- 1998-04-02 TR TR1999/00644T patent/TR199900644T2/xx unknown
- 1998-04-02 DE DE69824872T patent/DE69824872T2/de not_active Expired - Lifetime
- 1998-04-02 AP APAP/P/1999/001650A patent/AP1138A/en active
- 1998-04-02 SK SK287-99A patent/SK283621B6/sk not_active IP Right Cessation
- 1998-04-02 GE GEAP19985020A patent/GEP20022823B/en unknown
- 1998-04-02 EE EEP199900114A patent/EE03691B1/et not_active IP Right Cessation
- 1998-04-02 HU HU0003624A patent/HUP0003624A3/hu unknown
- 1998-04-03 MY MYPI98001502A patent/MY120033A/en unknown
- 1998-04-07 ZA ZA9802969A patent/ZA982969B/xx unknown
- 1998-04-07 AR ARP980101598A patent/AR012576A1/es active IP Right Grant
- 1998-04-07 TW TW087105162A patent/TW589315B/zh not_active IP Right Cessation
-
1999
- 1999-02-23 NO NO19990859A patent/NO322826B1/no not_active IP Right Cessation
- 1999-02-25 BG BG103213A patent/BG63848B1/bg unknown
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