ZA981885B - Method for the preparation of alpha-bromo-lactam derivatives - Google Patents

Method for the preparation of alpha-bromo-lactam derivatives

Info

Publication number
ZA981885B
ZA981885B ZA981885A ZA981885A ZA981885B ZA 981885 B ZA981885 B ZA 981885B ZA 981885 A ZA981885 A ZA 981885A ZA 981885 A ZA981885 A ZA 981885A ZA 981885 B ZA981885 B ZA 981885B
Authority
ZA
South Africa
Prior art keywords
bromo
alpha
preparation
lactam derivatives
lactam
Prior art date
Application number
ZA981885A
Other languages
English (en)
Inventor
Stefan Abrecht
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA981885B publication Critical patent/ZA981885B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA981885A 1997-03-10 1998-03-05 Method for the preparation of alpha-bromo-lactam derivatives ZA981885B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97103964 1997-03-10

Publications (1)

Publication Number Publication Date
ZA981885B true ZA981885B (en) 1998-09-10

Family

ID=8226572

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA981885A ZA981885B (en) 1997-03-10 1998-03-05 Method for the preparation of alpha-bromo-lactam derivatives

Country Status (16)

Country Link
US (1) US6114541A (xx)
EP (1) EP0864564B1 (xx)
JP (1) JP2938427B2 (xx)
KR (1) KR100280561B1 (xx)
CN (1) CN1193014A (xx)
AR (1) AR015571A1 (xx)
AT (1) ATE219056T1 (xx)
AU (1) AU728147B2 (xx)
BR (1) BR9800844A (xx)
CA (1) CA2231631A1 (xx)
CY (1) CY2392B1 (xx)
DE (1) DE69805887T2 (xx)
DK (1) DK0864564T3 (xx)
ES (1) ES2176841T3 (xx)
TR (1) TR199800403A3 (xx)
ZA (1) ZA981885B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901712D0 (sv) * 1999-05-11 1999-05-11 Astra Ab New process
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
TW201615643A (zh) 2014-06-02 2016-05-01 伊史帝夫博士實驗室股份有限公司 具有多重模式抗疼痛活性之1-氧雜-4,9-二氮雜螺十一烷化合物之烷基與芳基衍生物
TWI685497B (zh) 2014-06-02 2020-02-21 西班牙商伊史帝夫製藥公司 具有多重模式抗疼痛活性的1-氧雜-4,9-二氮雜螺十一烷化合物之烷基衍生物
PT3365338T (pt) 2015-10-23 2022-10-26 Esteve Pharmaceuticals Sa Derivados de morfolina substituídos tendo atividade contra a dor
EP3365345B1 (en) 2015-10-23 2020-02-26 Esteve Pharmaceuticals, S.A. Oxa-azaspiro compounds having activity against pain
CA2999925A1 (en) 2015-10-23 2017-04-27 Laboratorios Del Dr. Esteve, S.A. Oxa-diazaspiro compounds having activity against pain
UA123775C2 (uk) 2015-11-16 2021-06-02 Естев Фармас'Ютікалз, С.А. Оксадіазаспіросполуки для лікування зловживання наркотичними засобами та залежності від них
CN107129454A (zh) * 2017-05-04 2017-09-05 唐山威格化学工业有限公司 N‑辛基吡咯烷酮的合成方法
CN111263764A (zh) 2017-10-17 2020-06-09 埃斯蒂文制药股份有限公司 (r)-9-(2,5-二氟苯乙基)-4-乙基-2-甲基-1-氧杂-4,9-二氮杂螺[5.5]十一烷-3-酮的盐

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
DE69431691T2 (de) * 1993-04-16 2003-08-21 Basilea Pharmaceutica Ag Binni Cephalosporin-Derivate
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives

Also Published As

Publication number Publication date
AR015571A1 (es) 2001-05-16
TR199800403A2 (xx) 1998-09-21
TR199800403A3 (tr) 1998-09-21
JPH10273481A (ja) 1998-10-13
DE69805887D1 (de) 2002-07-18
DE69805887T2 (de) 2003-02-20
KR19980080035A (ko) 1998-11-25
JP2938427B2 (ja) 1999-08-23
EP0864564B1 (en) 2002-06-12
ATE219056T1 (de) 2002-06-15
ES2176841T3 (es) 2002-12-01
AU728147B2 (en) 2001-01-04
EP0864564A1 (en) 1998-09-16
US6114541A (en) 2000-09-05
BR9800844A (pt) 2000-05-02
CY2392B1 (en) 2004-09-10
CA2231631A1 (en) 1998-09-10
DK0864564T3 (da) 2002-09-23
KR100280561B1 (ko) 2001-02-01
CN1193014A (zh) 1998-09-16
AU5737498A (en) 1998-09-10

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