ZA981482B - Derivatives of erythromycin their preparation process and their use as medicaments - Google Patents
Derivatives of erythromycin their preparation process and their use as medicamentsInfo
- Publication number
- ZA981482B ZA981482B ZA981482A ZA981482A ZA981482B ZA 981482 B ZA981482 B ZA 981482B ZA 981482 A ZA981482 A ZA 981482A ZA 981482 A ZA981482 A ZA 981482A ZA 981482 B ZA981482 B ZA 981482B
- Authority
- ZA
- South Africa
- Prior art keywords
- erythromycin
- medicaments
- derivatives
- nar
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
The invention concerns compounds of formula (I) in which A and B form with the atoms to which they are bound a group (a): R1 = NH2, NH-alkyl, NH-alkenyl, NH-alkynyl, (CH2)nAr, NH(CH2)nAr or N=NH(CH2)nAr, Ar = aryl or heteroaryl, optionally substituted; R = H, alkyl optionally substituted, optionally interrupted by one or several heteroatoms, aryl or heteroaryl, optionally substituted, as well as the salts of compounds of formula (I). The compounds of formula (I) have interesting antibiotic properties.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9702352A FR2760017B1 (en) | 1997-02-27 | 1997-02-27 | NOVEL ERYTROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA981482B true ZA981482B (en) | 1999-02-23 |
Family
ID=9504247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA981482A ZA981482B (en) | 1997-02-27 | 1998-02-23 | Derivatives of erythromycin their preparation process and their use as medicaments |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0968222B1 (en) |
| JP (1) | JP4531136B2 (en) |
| KR (1) | KR100529980B1 (en) |
| CN (1) | CN1162442C (en) |
| AT (1) | ATE219097T1 (en) |
| AU (1) | AU728182B2 (en) |
| BR (1) | BR9807795A (en) |
| CA (1) | CA2282666C (en) |
| DE (1) | DE69805981T2 (en) |
| DK (1) | DK0968222T3 (en) |
| EA (1) | EA002359B1 (en) |
| ES (1) | ES2179475T3 (en) |
| FR (1) | FR2760017B1 (en) |
| HU (1) | HUP0001245A3 (en) |
| IL (1) | IL131340A0 (en) |
| NO (1) | NO315653B1 (en) |
| PL (1) | PL187947B1 (en) |
| PT (1) | PT968222E (en) |
| TR (1) | TR199902092T2 (en) |
| WO (1) | WO1998038199A1 (en) |
| ZA (1) | ZA981482B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2782239A1 (en) | 1998-08-13 | 2000-02-18 | Euromark | Hopper for distributing animal provisions, consists of hopper with means of ejecting food and fitted with scraper to distribute products over ground |
| ES2243066T3 (en) | 1998-09-22 | 2005-11-16 | Pfizer Products Inc. | CARBAMATE AND CETOLID CARBAZATE ANTIBIOTICS. |
| SI1147121T1 (en) | 1999-01-27 | 2004-04-30 | Pfizer Products Inc. | Ketolide antibiotics |
| MXPA01010524A (en) * | 1999-04-16 | 2002-03-14 | Kosan Biosciences Inc | Macrolide antiinfective agents. |
| EE200100613A (en) | 1999-05-24 | 2003-02-17 | Pfizer Products Inc. | 13-methylerythromycin derivatives |
| ID27331A (en) * | 1999-09-29 | 2001-03-29 | Pfizer Prod Inc | MAKING ANTIBIOTIC-ANTIBIOTIC KETOLIDA CARBAMATE |
| US6673774B2 (en) | 2001-12-03 | 2004-01-06 | Enanta Pharmaceuticals, Inc. | 11-O-substituted macrolides and their descladinose derivatives |
| US6670331B2 (en) | 2001-12-04 | 2003-12-30 | Enanta Pharmaceuticals, Inc. | 11-O-substituted ketolide derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2473525A1 (en) * | 1980-01-11 | 1981-07-17 | Roussel Uclaf | NOVEL OXIMES DERIVED FROM ERYTHROMYCIN, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS |
| IL99995A (en) * | 1990-11-21 | 1997-11-20 | Roussel Uclaf | Erythromycin derivatives, their preparation and pharmaceutical compositions containing them |
| US5527780A (en) * | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
| FR2702480B1 (en) * | 1993-03-09 | 1995-04-28 | Roussel Uclaf | New erythromycin derivatives, their preparation process and their use as drugs. |
| FR2718450B1 (en) * | 1994-04-08 | 1997-01-10 | Roussel Uclaf | New erythromycin derivatives, their preparation process and their use as drugs. |
| FR2719587B1 (en) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | New erythromycin derivatives, their preparation process and their use as drugs. |
-
1997
- 1997-02-27 FR FR9702352A patent/FR2760017B1/en not_active Expired - Fee Related
-
1998
- 1998-02-23 ZA ZA981482A patent/ZA981482B/en unknown
- 1998-02-26 DK DK98912554T patent/DK0968222T3/en active
- 1998-02-26 CN CNB988027623A patent/CN1162442C/en not_active Expired - Lifetime
- 1998-02-26 DE DE69805981T patent/DE69805981T2/en not_active Expired - Lifetime
- 1998-02-26 CA CA002282666A patent/CA2282666C/en not_active Expired - Lifetime
- 1998-02-26 EP EP98912554A patent/EP0968222B1/en not_active Expired - Lifetime
- 1998-02-26 HU HU0001245A patent/HUP0001245A3/en unknown
- 1998-02-26 JP JP53738298A patent/JP4531136B2/en not_active Expired - Lifetime
- 1998-02-26 BR BR9807795-3A patent/BR9807795A/en not_active Application Discontinuation
- 1998-02-26 EA EA199900765A patent/EA002359B1/en not_active IP Right Cessation
- 1998-02-26 ES ES98912554T patent/ES2179475T3/en not_active Expired - Lifetime
- 1998-02-26 IL IL13134098A patent/IL131340A0/en not_active IP Right Cessation
- 1998-02-26 WO PCT/FR1998/000378 patent/WO1998038199A1/en not_active Application Discontinuation
- 1998-02-26 TR TR1999/02092T patent/TR199902092T2/en unknown
- 1998-02-26 PT PT98912554T patent/PT968222E/en unknown
- 1998-02-26 PL PL33537598A patent/PL187947B1/en not_active IP Right Cessation
- 1998-02-26 KR KR10-1999-7007791A patent/KR100529980B1/en not_active IP Right Cessation
- 1998-02-26 AU AU67347/98A patent/AU728182B2/en not_active Expired
- 1998-02-26 AT AT98912554T patent/ATE219097T1/en active
-
1999
- 1999-08-27 NO NO19994150A patent/NO315653B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2179475T3 (en) | 2003-01-16 |
| JP2001513101A (en) | 2001-08-28 |
| KR100529980B1 (en) | 2005-11-22 |
| AU728182B2 (en) | 2001-01-04 |
| CN1162442C (en) | 2004-08-18 |
| ATE219097T1 (en) | 2002-06-15 |
| PL335375A1 (en) | 2000-04-25 |
| HUP0001245A1 (en) | 2000-09-28 |
| WO1998038199A1 (en) | 1998-09-03 |
| FR2760017B1 (en) | 1999-04-30 |
| EA199900765A1 (en) | 2000-04-24 |
| CA2282666A1 (en) | 1998-09-03 |
| NO994150D0 (en) | 1999-08-27 |
| FR2760017A1 (en) | 1998-08-28 |
| IL131340A0 (en) | 2001-01-28 |
| EP0968222A1 (en) | 2000-01-05 |
| NO994150L (en) | 1999-08-27 |
| CN1248261A (en) | 2000-03-22 |
| AU6734798A (en) | 1998-09-18 |
| HUP0001245A3 (en) | 2003-05-28 |
| NO315653B1 (en) | 2003-10-06 |
| DE69805981D1 (en) | 2002-07-18 |
| TR199902092T2 (en) | 2000-05-22 |
| CA2282666C (en) | 2008-09-02 |
| DK0968222T3 (en) | 2002-10-07 |
| PT968222E (en) | 2002-10-31 |
| KR20000075722A (en) | 2000-12-26 |
| PL187947B1 (en) | 2004-11-30 |
| EP0968222B1 (en) | 2002-06-12 |
| DE69805981T2 (en) | 2003-01-16 |
| BR9807795A (en) | 2000-02-15 |
| EA002359B1 (en) | 2002-04-25 |
| JP4531136B2 (en) | 2010-08-25 |
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