DK0968222T3 - Erythromycin derivatives, processes for their preparation and their use as drugs - Google Patents
Erythromycin derivatives, processes for their preparation and their use as drugsInfo
- Publication number
- DK0968222T3 DK0968222T3 DK98912554T DK98912554T DK0968222T3 DK 0968222 T3 DK0968222 T3 DK 0968222T3 DK 98912554 T DK98912554 T DK 98912554T DK 98912554 T DK98912554 T DK 98912554T DK 0968222 T3 DK0968222 T3 DK 0968222T3
- Authority
- DK
- Denmark
- Prior art keywords
- drugs
- processes
- preparation
- nar
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
The invention concerns compounds of formula (I) in which A and B form with the atoms to which they are bound a group (a): R1 = NH2, NH-alkyl, NH-alkenyl, NH-alkynyl, (CH2)nAr, NH(CH2)nAr or N=NH(CH2)nAr, Ar = aryl or heteroaryl, optionally substituted; R = H, alkyl optionally substituted, optionally interrupted by one or several heteroatoms, aryl or heteroaryl, optionally substituted, as well as the salts of compounds of formula (I). The compounds of formula (I) have interesting antibiotic properties.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9702352A FR2760017B1 (en) | 1997-02-27 | 1997-02-27 | NOVEL ERYTROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
| PCT/FR1998/000378 WO1998038199A1 (en) | 1997-02-27 | 1998-02-26 | Novel erythromycin derivatives, method of preparation and application as medicines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0968222T3 true DK0968222T3 (en) | 2002-10-07 |
Family
ID=9504247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98912554T DK0968222T3 (en) | 1997-02-27 | 1998-02-26 | Erythromycin derivatives, processes for their preparation and their use as drugs |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0968222B1 (en) |
| JP (1) | JP4531136B2 (en) |
| KR (1) | KR100529980B1 (en) |
| CN (1) | CN1162442C (en) |
| AT (1) | ATE219097T1 (en) |
| AU (1) | AU728182B2 (en) |
| BR (1) | BR9807795A (en) |
| CA (1) | CA2282666C (en) |
| DE (1) | DE69805981T2 (en) |
| DK (1) | DK0968222T3 (en) |
| EA (1) | EA002359B1 (en) |
| ES (1) | ES2179475T3 (en) |
| FR (1) | FR2760017B1 (en) |
| HU (1) | HUP0001245A3 (en) |
| IL (1) | IL131340A0 (en) |
| NO (1) | NO315653B1 (en) |
| PL (1) | PL187947B1 (en) |
| PT (1) | PT968222E (en) |
| TR (1) | TR199902092T2 (en) |
| WO (1) | WO1998038199A1 (en) |
| ZA (1) | ZA981482B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2782239A1 (en) | 1998-08-13 | 2000-02-18 | Euromark | Hopper for distributing animal provisions, consists of hopper with means of ejecting food and fitted with scraper to distribute products over ground |
| WO2000017218A1 (en) | 1998-09-22 | 2000-03-30 | Pfizer Products Inc. | Carbamate and carbazate ketolide antibiotics |
| EP1147121B1 (en) | 1999-01-27 | 2003-12-17 | Pfizer Products Inc. | Ketolide antibiotics |
| KR20020007374A (en) * | 1999-04-16 | 2002-01-26 | 추후제출 | Macrolide antiinfective agents |
| WO2000071557A1 (en) | 1999-05-24 | 2000-11-30 | Pfizer Products Inc. | 13-methyl-erythromycin derivatives |
| ID27331A (en) * | 1999-09-29 | 2001-03-29 | Pfizer Prod Inc | MAKING ANTIBIOTIC-ANTIBIOTIC KETOLIDA CARBAMATE |
| US6673774B2 (en) | 2001-12-03 | 2004-01-06 | Enanta Pharmaceuticals, Inc. | 11-O-substituted macrolides and their descladinose derivatives |
| US6670331B2 (en) | 2001-12-04 | 2003-12-30 | Enanta Pharmaceuticals, Inc. | 11-O-substituted ketolide derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2473525A1 (en) * | 1980-01-11 | 1981-07-17 | Roussel Uclaf | NOVEL OXIMES DERIVED FROM ERYTHROMYCIN, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS |
| IL114589A (en) * | 1990-11-21 | 1999-12-22 | Roussel Uclaf | Intermediates for the preparation of erythromycin derivatives |
| US5527780A (en) * | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
| FR2702480B1 (en) * | 1993-03-09 | 1995-04-28 | Roussel Uclaf | New erythromycin derivatives, their preparation process and their use as drugs. |
| FR2718450B1 (en) * | 1994-04-08 | 1997-01-10 | Roussel Uclaf | New erythromycin derivatives, their preparation process and their use as drugs. |
| FR2719587B1 (en) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | New erythromycin derivatives, their preparation process and their use as drugs. |
-
1997
- 1997-02-27 FR FR9702352A patent/FR2760017B1/en not_active Expired - Fee Related
-
1998
- 1998-02-23 ZA ZA981482A patent/ZA981482B/en unknown
- 1998-02-26 HU HU0001245A patent/HUP0001245A3/en unknown
- 1998-02-26 WO PCT/FR1998/000378 patent/WO1998038199A1/en not_active Application Discontinuation
- 1998-02-26 DE DE69805981T patent/DE69805981T2/en not_active Expired - Lifetime
- 1998-02-26 EA EA199900765A patent/EA002359B1/en not_active IP Right Cessation
- 1998-02-26 AU AU67347/98A patent/AU728182B2/en not_active Expired
- 1998-02-26 PL PL33537598A patent/PL187947B1/en not_active IP Right Cessation
- 1998-02-26 DK DK98912554T patent/DK0968222T3/en active
- 1998-02-26 PT PT98912554T patent/PT968222E/en unknown
- 1998-02-26 ES ES98912554T patent/ES2179475T3/en not_active Expired - Lifetime
- 1998-02-26 JP JP53738298A patent/JP4531136B2/en not_active Expired - Lifetime
- 1998-02-26 AT AT98912554T patent/ATE219097T1/en active
- 1998-02-26 CN CNB988027623A patent/CN1162442C/en not_active Expired - Lifetime
- 1998-02-26 IL IL13134098A patent/IL131340A0/en not_active IP Right Cessation
- 1998-02-26 EP EP98912554A patent/EP0968222B1/en not_active Expired - Lifetime
- 1998-02-26 BR BR9807795-3A patent/BR9807795A/en not_active Application Discontinuation
- 1998-02-26 TR TR1999/02092T patent/TR199902092T2/en unknown
- 1998-02-26 KR KR10-1999-7007791A patent/KR100529980B1/en not_active IP Right Cessation
- 1998-02-26 CA CA002282666A patent/CA2282666C/en not_active Expired - Lifetime
-
1999
- 1999-08-27 NO NO19994150A patent/NO315653B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6734798A (en) | 1998-09-18 |
| PL187947B1 (en) | 2004-11-30 |
| TR199902092T2 (en) | 2000-05-22 |
| WO1998038199A1 (en) | 1998-09-03 |
| JP4531136B2 (en) | 2010-08-25 |
| HUP0001245A1 (en) | 2000-09-28 |
| AU728182B2 (en) | 2001-01-04 |
| NO315653B1 (en) | 2003-10-06 |
| ATE219097T1 (en) | 2002-06-15 |
| EA199900765A1 (en) | 2000-04-24 |
| BR9807795A (en) | 2000-02-15 |
| NO994150D0 (en) | 1999-08-27 |
| KR20000075722A (en) | 2000-12-26 |
| FR2760017B1 (en) | 1999-04-30 |
| KR100529980B1 (en) | 2005-11-22 |
| EP0968222B1 (en) | 2002-06-12 |
| ES2179475T3 (en) | 2003-01-16 |
| NO994150L (en) | 1999-08-27 |
| FR2760017A1 (en) | 1998-08-28 |
| CA2282666C (en) | 2008-09-02 |
| CA2282666A1 (en) | 1998-09-03 |
| CN1248261A (en) | 2000-03-22 |
| PT968222E (en) | 2002-10-31 |
| PL335375A1 (en) | 2000-04-25 |
| EA002359B1 (en) | 2002-04-25 |
| EP0968222A1 (en) | 2000-01-05 |
| DE69805981T2 (en) | 2003-01-16 |
| CN1162442C (en) | 2004-08-18 |
| ZA981482B (en) | 1999-02-23 |
| DE69805981D1 (en) | 2002-07-18 |
| JP2001513101A (en) | 2001-08-28 |
| IL131340A0 (en) | 2001-01-28 |
| HUP0001245A3 (en) | 2003-05-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200970171A1 (en) | DERIVATIVES N- (AMINOHETEROARIL) -1H-INDOL-2-CARBOXAMIDES, THEIR RECEIVING AND THEIR APPLICATION IN THERAPY | |
| EA199901016A1 (en) | 9-OXYM DERIVATIVES OF ERYTHROMYCIN | |
| WO2007048065A3 (en) | Pyrimidinones as casein kinase ii (ck2) modulators | |
| ECSP055974A (en) | SYNTHESIS OF CHLORIDES OF 4 AMINO-2-BUTENOIL AND ITS USE IN THE PREPARATION OF 3-CYANO QUINOLINAS | |
| AP9801378A0 (en) | 9-amino-3- keto erythromycin derivatives. | |
| BRPI0413151A (en) | amino propanol derivatives | |
| EA200702375A1 (en) | UREA DERIVATIVES, METHODS FOR THEIR RECEPTION AND APPLICATION | |
| MX2009007954A (en) | Heterocyclidene-n-(aryl)acetamide derivative. | |
| DK1517890T3 (en) | Cationically substituted diphenyllazetidinones, processes for their preparation, drugs containing these compounds and their use | |
| NO20062202L (en) | Amidomethyl-substituted 2- (4-sulfonylamino) -3-hydroxy-3,4-dihydro-2H-chromene-6-yl derivatives, processes and intermediates for their preparation, and drugs containing these compounds | |
| DK0968222T3 (en) | Erythromycin derivatives, processes for their preparation and their use as drugs | |
| BR0315302A (en) | Substituted benzoxazinones and their uses | |
| ATE277062T1 (en) | NEW MACROLIDE DERIVATIVES | |
| CA2302943A1 (en) | Phthalazine compounds and therapeutic agents for erectile dysfunction | |
| BRPI0407386A (en) | Amino alcohol derivatives, pharmaceutical compositions containing same and use thereof | |
| CY1105550T1 (en) | MEMNO-PEPTIDES, A PROCEDURE FOR THEIR PREPARATION AND USE | |
| BRPI0207102A8 (en) | crystalline form, pharmaceutical composition, and use of a crystalline form. | |
| DK1532098T3 (en) | Process for the preparation of nitro oxide derivatives of naproxen | |
| DK1325923T3 (en) | Cephem compounds and ESBL-detecting reagents containing them | |
| ATE509911T1 (en) | COMPOUNDS THAT BIND TO THE MINOR GROWTH OF DNA | |
| CY1106321T1 (en) | NEW SEMI-SYNTHETIC MACROLIDE ANTIBIOTICS OF THE AZALIDE SERIES | |
| NO20002321L (en) | Biphenyl derivatives as pharmaceutical agents | |
| DK1000952T3 (en) | New 2-halogen derivatives of 5-O-deosaminyl erythronolide A, process for their preparation and use thereof as pharmaceuticals | |
| NO993124L (en) | New erythromycin derivatives, processes for their preparation and their use as medicines | |
| IT1213440B (en) | 2-DITHIOALKYL-DIHYDROPYRIDINE, A METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS WHICH CONTAIN. |