ZA9810834B - Pyrrole compounds a process for their preparation and pharmaceutical compositions containing them - Google Patents

Pyrrole compounds a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA9810834B
ZA9810834B ZA9810834A ZA9810834A ZA9810834B ZA 9810834 B ZA9810834 B ZA 9810834B ZA 9810834 A ZA9810834 A ZA 9810834A ZA 9810834 A ZA9810834 A ZA 9810834A ZA 9810834 B ZA9810834 B ZA 9810834B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
preparation
compositions containing
cycloalkyl
pyrrole compounds
Prior art date
Application number
ZA9810834A
Other languages
English (en)
Inventor
Guillaume De Nanteuil
Bernard Portevin
Jacqueline Bonnet
Charles Tordjman
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA9810834B publication Critical patent/ZA9810834B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/724,7-Endo-alkylene-iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9810834A 1997-11-26 1998-11-26 Pyrrole compounds a process for their preparation and pharmaceutical compositions containing them ZA9810834B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714840A FR2771412B1 (fr) 1997-11-26 1997-11-26 Nouveaux derives de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA9810834B true ZA9810834B (en) 1999-05-31

Family

ID=9513802

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810834A ZA9810834B (en) 1997-11-26 1998-11-26 Pyrrole compounds a process for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (2) US6063804A (ja)
EP (1) EP0921119B1 (ja)
JP (1) JPH11228538A (ja)
CN (1) CN1126737C (ja)
AT (1) ATE244221T1 (ja)
AU (1) AU739179B2 (ja)
BR (1) BR9805053A (ja)
CA (1) CA2254521C (ja)
DE (1) DE69816004T2 (ja)
DK (1) DK0921119T3 (ja)
ES (1) ES2202775T3 (ja)
FR (1) FR2771412B1 (ja)
HK (1) HK1020945A1 (ja)
HU (1) HUP9802749A2 (ja)
NO (1) NO311716B1 (ja)
NZ (1) NZ333000A (ja)
PL (1) PL329894A1 (ja)
PT (1) PT921119E (ja)
ZA (1) ZA9810834B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
ES2236007T3 (es) * 1999-12-08 2005-07-16 Pharmacia Corporation Composiciones de inhibidor de ciclooxigenasa-2 ue tiene un efecto terapeutico rapido.
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US7695736B2 (en) 2001-04-03 2010-04-13 Pfizer Inc. Reconstitutable parenteral composition
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
KR100821915B1 (ko) 2006-11-10 2008-04-16 한양대학교 산학협력단 2번 위치에 엑소 메틸렌기를 가지는 고리화합물이 치환된 다중 고리화합물 및 이의 제조방법
EP2838881B1 (en) * 2012-04-20 2018-08-08 AbbVie Inc. Isoindolone derivatives
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417202B1 (en) * 1996-07-11 2002-07-09 Pfizer Inc. Pyridylpyrrole compounds useful as interleukin-and TNF antagonists

Also Published As

Publication number Publication date
EP0921119A1 (fr) 1999-06-09
CN1126737C (zh) 2003-11-05
NO311716B1 (no) 2002-01-14
ATE244221T1 (de) 2003-07-15
FR2771412B1 (fr) 2000-04-28
HUP9802749A2 (hu) 2001-02-28
DE69816004T2 (de) 2004-04-29
NO985495L (no) 1999-05-27
CA2254521A1 (fr) 1999-05-26
CN1222509A (zh) 1999-07-14
FR2771412A1 (fr) 1999-05-28
EP0921119B1 (fr) 2003-07-02
HU9802749D0 (en) 1999-01-28
PL329894A1 (en) 1999-06-07
PT921119E (pt) 2003-10-31
ES2202775T3 (es) 2004-04-01
CA2254521C (fr) 2003-10-28
US6063804A (en) 2000-05-16
AU739179B2 (en) 2001-10-04
DK0921119T3 (da) 2003-10-20
NO985495D0 (no) 1998-11-25
NZ333000A (en) 2000-04-28
HK1020945A1 (en) 2000-05-26
DE69816004D1 (de) 2003-08-07
US6114360A (en) 2000-09-05
BR9805053A (pt) 2000-02-01
AU9416598A (en) 1999-06-17
JPH11228538A (ja) 1999-08-24

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