ATE244221T1 - Pyrrolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Pyrrolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE244221T1
ATE244221T1 AT98402926T AT98402926T ATE244221T1 AT E244221 T1 ATE244221 T1 AT E244221T1 AT 98402926 T AT98402926 T AT 98402926T AT 98402926 T AT98402926 T AT 98402926T AT E244221 T1 ATE244221 T1 AT E244221T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
production
compositions containing
containing same
pyrrole derivatives
Prior art date
Application number
AT98402926T
Other languages
English (en)
Inventor
Nanteuil Guillaume De
Bernard Portevin
Jacqueline Bonnet
Charles Tordjman
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of ATE244221T1 publication Critical patent/ATE244221T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/724,7-Endo-alkylene-iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT98402926T 1997-11-26 1998-11-25 Pyrrolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen ATE244221T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714840A FR2771412B1 (fr) 1997-11-26 1997-11-26 Nouveaux derives de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE244221T1 true ATE244221T1 (de) 2003-07-15

Family

ID=9513802

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98402926T ATE244221T1 (de) 1997-11-26 1998-11-25 Pyrrolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (19)

Country Link
US (2) US6063804A (de)
EP (1) EP0921119B1 (de)
JP (1) JPH11228538A (de)
CN (1) CN1126737C (de)
AT (1) ATE244221T1 (de)
AU (1) AU739179B2 (de)
BR (1) BR9805053A (de)
CA (1) CA2254521C (de)
DE (1) DE69816004T2 (de)
DK (1) DK0921119T3 (de)
ES (1) ES2202775T3 (de)
FR (1) FR2771412B1 (de)
HK (1) HK1020945A1 (de)
HU (1) HUP9802749A2 (de)
NO (1) NO311716B1 (de)
NZ (1) NZ333000A (de)
PL (1) PL329894A1 (de)
PT (1) PT921119E (de)
ZA (1) ZA9810834B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
BR0008060A (pt) * 1999-12-08 2002-02-05 Pharmacia Corp Composições inibidoras de ciclooxigenase-2 tendo rápido inìcio de eficácia terapêutica
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
PE20021017A1 (es) 2001-04-03 2002-11-24 Pharmacia Corp Composicion parenteral reconstituible
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
KR100821915B1 (ko) 2006-11-10 2008-04-16 한양대학교 산학협력단 2번 위치에 엑소 메틸렌기를 가지는 고리화합물이 치환된 다중 고리화합물 및 이의 제조방법
CA2870931A1 (en) * 2012-04-20 2013-10-24 Abbvie Inc. Isoindolone derivatives
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417202B1 (en) * 1996-07-11 2002-07-09 Pfizer Inc. Pyridylpyrrole compounds useful as interleukin-and TNF antagonists

Also Published As

Publication number Publication date
PT921119E (pt) 2003-10-31
US6063804A (en) 2000-05-16
HK1020945A1 (en) 2000-05-26
JPH11228538A (ja) 1999-08-24
PL329894A1 (en) 1999-06-07
NO311716B1 (no) 2002-01-14
CN1126737C (zh) 2003-11-05
HUP9802749A2 (hu) 2001-02-28
BR9805053A (pt) 2000-02-01
FR2771412B1 (fr) 2000-04-28
CA2254521C (fr) 2003-10-28
DE69816004D1 (de) 2003-08-07
NZ333000A (en) 2000-04-28
AU9416598A (en) 1999-06-17
US6114360A (en) 2000-09-05
NO985495L (no) 1999-05-27
CA2254521A1 (fr) 1999-05-26
HU9802749D0 (en) 1999-01-28
NO985495D0 (no) 1998-11-25
ZA9810834B (en) 1999-05-31
EP0921119B1 (de) 2003-07-02
EP0921119A1 (de) 1999-06-09
AU739179B2 (en) 2001-10-04
DK0921119T3 (da) 2003-10-20
CN1222509A (zh) 1999-07-14
DE69816004T2 (de) 2004-04-29
FR2771412A1 (fr) 1999-05-28
ES2202775T3 (es) 2004-04-01

Similar Documents

Publication Publication Date Title
SE9203318D0 (sv) Novel 3,3-diphenylpropylamines, their use and preparation
ATE150462T1 (de) Pyrazolopyridinverbindungen und verfahren zu ihrer herstellung
DE69110625D1 (de) Oxazolopyridinderivate, Verfahren zu ihrer Herstellung und die sie enthaltenden pharmazeutischen Zusammensetzungen.
ES2029384T3 (es) Procedimiento para preparar nuevas 3,3-difenilpropilaminas.
ATE244221T1 (de) Pyrrolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
NO940523D0 (no) Nye pyrazin-derivater
AR036176A1 (es) Un derivado de fenil-acetamido-tiazol, un procedimiento para su preparacion, una composicion farmaceutica que lo comprende, un producto o kit que los comprende, y un metodo que utiliza dicho derivado
WO2002007677A3 (en) Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder
DE3575554D1 (de) Aminosaeurederivate mit antitumoraktivitaet sowie diese derivate enthaltende zusammensetzungen.
AR042547A1 (es) Uso de acidos alfa - feniltiocaboxilico y alfa - feniloxicarboxilico con actividad disminuidora de la glucosa en el suero y de los lipidos en el suero
ATE214051T1 (de) Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DK0861250T3 (da) Amindin- og isothiourinstofderivater som inhibitorer for nitrogenmonoxidsyntase
DE68906572D1 (de) Peptide mit inhibitorischer wirkung auf enzymatische systeme, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE3787844D1 (de) Thioester und dessen Verwendung zur Herstellung von pharmazeutischen Zusammensetzungen zur Behandlung von Ischämie und von Reperfusion-Syndromen.
HRP20000733B1 (en) NOVEL OCTAHYDRO-6,10-DIOXO-6H-PYRIDAZINO/1,2-a/ /1,2/DIAZEPIN-1-CARBOXYLIC ACID DERIVATIVES, PREPARATION METHOD AND USE FOR PREPARING THERAPEUTICALLY ACTIVE COMPOUNDS
EA200101204A1 (ru) Новые бициклические соединения аминопиразинона, способ их получения и содержащие их фармацевтические композиции
ATE86993T1 (de) Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ATE7137T1 (de) Nitrosoureum-derivate, verfahren zu deren herstellung, und diese enthaltende pharmazeutische zusammensetzungen.
EA200000527A2 (ru) Новые бициклические амино-пиразиноновые соединения, способ их получения и фармацевтические композиции, содержащие их
DE68909451D1 (de) Peptide mit inhibitorischer wirkung auf enzymatische systeme, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
TH37589A (th) อนุพันธ์พิริดีนชนิดใหม่และสารผสมทางเภสัชกรรมที่มีสารเหล่านี้
TH6636EX (th) อนุพันธ์ของควิโนลีน กรรมวิธีสำหรับการเตรียมสารเหล่านั้นและสารต่อต้านแบคทีเรีย ที่มีสารเหล่านั้นอนุพันธ์ของควิโนลีน กรรมวิธีสำหรับการเตรียมสารเหล่านั้นและสารต่อต้านแบคทีเรีย ที่มีสารเหล่านั้น

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0921119

Country of ref document: EP

REN Ceased due to non-payment of the annual fee