ZA978652B - Flavone compounds, process for preparing them and pharmaceutical compositions containing them. - Google Patents

Flavone compounds, process for preparing them and pharmaceutical compositions containing them.

Info

Publication number
ZA978652B
ZA978652B ZA9708652A ZA978652A ZA978652B ZA 978652 B ZA978652 B ZA 978652B ZA 9708652 A ZA9708652 A ZA 9708652A ZA 978652 A ZA978652 A ZA 978652A ZA 978652 B ZA978652 B ZA 978652B
Authority
ZA
South Africa
Prior art keywords
alkyl
optionally substituted
alkoxy
optionally
aryl
Prior art date
Application number
ZA9708652A
Other languages
English (en)
Inventor
Alain Dhainaut
Guy Lewin
Emmanuel Canet
Michel Lonchampt
Yves Rolland
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA978652B publication Critical patent/ZA978652B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9708652A 1996-09-27 1997-09-26 Flavone compounds, process for preparing them and pharmaceutical compositions containing them. ZA978652B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611808A FR2753969B1 (fr) 1996-09-27 1996-09-27 Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA978652B true ZA978652B (en) 1998-03-27

Family

ID=9496129

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9708652A ZA978652B (en) 1996-09-27 1997-09-26 Flavone compounds, process for preparing them and pharmaceutical compositions containing them.

Country Status (18)

Country Link
US (1) US5889003A (no)
EP (1) EP0832886B1 (no)
JP (1) JPH10114766A (no)
CN (1) CN1094936C (no)
AT (1) ATE227712T1 (no)
AU (1) AU728990B2 (no)
BR (1) BR9704900A (no)
CA (1) CA2216617C (no)
DE (1) DE69717044T2 (no)
DK (1) DK0832886T3 (no)
ES (1) ES2187738T3 (no)
FR (1) FR2753969B1 (no)
HU (1) HUP9701588A3 (no)
NO (1) NO974455L (no)
NZ (1) NZ328858A (no)
PL (1) PL322297A1 (no)
PT (1) PT832886E (no)
ZA (1) ZA978652B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997011692A2 (en) * 1995-09-11 1997-04-03 Osteoarthritis Sciences, Inc. Protein tyrosine kinase inhibitors for treating osteoarthritis
PL346271A1 (en) 1998-08-26 2002-01-28 Smithkline Beecham Corp Therapies for treating pulmonary diseases
KR20010079922A (ko) * 1998-09-24 2001-08-22 미우라 아키라 하이드록시플라본 유도체
MXPA02001830A (es) 1999-08-21 2002-08-12 Byk Gulden Lomberg Chem Fab Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor.
US6806257B1 (en) 1999-10-20 2004-10-19 Board Of Trustees Of Southern Illinois University Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators
US6334998B1 (en) * 1999-12-07 2002-01-01 Parker Hughes Institute Estrogens for treating ALS
EP1127572A3 (en) * 2000-02-25 2003-05-02 Basf Aktiengesellschaft Use of flavones for treating cycloxygenase-2 mediated diseases
US6472436B1 (en) * 2000-07-17 2002-10-29 The Salk Institute For Biological Studies Methods for protecting cells from amyloid toxicity and for inhibiting amyloid protein production
DE10104350A1 (de) * 2001-02-01 2002-08-14 Merck Patent Gmbh Verfahren zur Herstellung von Flavon Derivaten
DE10232595A1 (de) * 2002-07-18 2004-02-05 Merck Patent Gmbh Lichtschutzmittel
EA200501548A1 (ru) 2003-04-01 2006-02-24 Апплайд Резеч Системз Арс Холдинг Н.В. Ингибиторы фосфодиэстераз при бесплодии
JP5058481B2 (ja) * 2005-11-28 2012-10-24 丸善製薬株式会社 角化細胞増殖剤、サイクリックａｍｐホスホジエステラーゼ阻害剤、及び保湿剤
US20100056791A1 (en) * 2006-09-01 2010-03-04 Yasushi Kohno Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same
CN101148444A (zh) * 2006-09-20 2008-03-26 上海特化医药科技有限公司 黄酮衍生物、制备方法及应用
KR100930467B1 (ko) 2007-06-07 2009-12-08 동아제약주식회사 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도
JP4559531B1 (ja) * 2009-12-03 2010-10-06 ウシオケミックス株式会社 ノビレチンの製造方法
CN103059005B (zh) * 2012-11-22 2015-04-22 中南民族大学 白杨素酰胺衍生物及其医药用途
CN105906598B (zh) * 2016-05-19 2018-05-08 江苏耐雀生物工程技术有限公司 白杨素衍生物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623808B1 (fr) * 1987-12-01 1990-03-09 Adir Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2748025B1 (fr) * 1996-04-25 1998-10-30 Adir Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CN1094936C (zh) 2002-11-27
DE69717044T2 (de) 2003-07-24
EP0832886A1 (fr) 1998-04-01
CA2216617C (fr) 2002-12-03
DE69717044D1 (de) 2002-12-19
HUP9701588A2 (hu) 1998-12-28
HU9701588D0 (en) 1997-11-28
FR2753969A1 (fr) 1998-04-03
NO974455D0 (no) 1997-09-26
DK0832886T3 (da) 2003-03-10
FR2753969B1 (fr) 1998-10-30
PL322297A1 (en) 1998-03-30
AU728990B2 (en) 2001-01-25
ATE227712T1 (de) 2002-11-15
AU3927197A (en) 1998-04-02
NO974455L (no) 1998-03-30
PT832886E (pt) 2003-03-31
CN1179422A (zh) 1998-04-22
CA2216617A1 (fr) 1998-03-27
US5889003A (en) 1999-03-30
JPH10114766A (ja) 1998-05-06
NZ328858A (en) 1998-01-26
EP0832886B1 (fr) 2002-11-13
BR9704900A (pt) 1998-10-27
HUP9701588A3 (en) 1999-03-01
ES2187738T3 (es) 2003-06-16

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