ZA978652B - Flavone compounds, process for preparing them and pharmaceutical compositions containing them. - Google Patents
Flavone compounds, process for preparing them and pharmaceutical compositions containing them.Info
- Publication number
- ZA978652B ZA978652B ZA9708652A ZA978652A ZA978652B ZA 978652 B ZA978652 B ZA 978652B ZA 9708652 A ZA9708652 A ZA 9708652A ZA 978652 A ZA978652 A ZA 978652A ZA 978652 B ZA978652 B ZA 978652B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- optionally substituted
- alkoxy
- optionally
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9611808A FR2753969B1 (fr) | 1996-09-27 | 1996-09-27 | Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA978652B true ZA978652B (en) | 1998-03-27 |
Family
ID=9496129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9708652A ZA978652B (en) | 1996-09-27 | 1997-09-26 | Flavone compounds, process for preparing them and pharmaceutical compositions containing them. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5889003A (no) |
EP (1) | EP0832886B1 (no) |
JP (1) | JPH10114766A (no) |
CN (1) | CN1094936C (no) |
AT (1) | ATE227712T1 (no) |
AU (1) | AU728990B2 (no) |
BR (1) | BR9704900A (no) |
CA (1) | CA2216617C (no) |
DE (1) | DE69717044T2 (no) |
DK (1) | DK0832886T3 (no) |
ES (1) | ES2187738T3 (no) |
FR (1) | FR2753969B1 (no) |
HU (1) | HUP9701588A3 (no) |
NO (1) | NO974455L (no) |
NZ (1) | NZ328858A (no) |
PL (1) | PL322297A1 (no) |
PT (1) | PT832886E (no) |
ZA (1) | ZA978652B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997011692A2 (en) * | 1995-09-11 | 1997-04-03 | Osteoarthritis Sciences, Inc. | Protein tyrosine kinase inhibitors for treating osteoarthritis |
PL346271A1 (en) | 1998-08-26 | 2002-01-28 | Smithkline Beecham Corp | Therapies for treating pulmonary diseases |
KR20010079922A (ko) * | 1998-09-24 | 2001-08-22 | 미우라 아키라 | 하이드록시플라본 유도체 |
MXPA02001830A (es) | 1999-08-21 | 2002-08-12 | Byk Gulden Lomberg Chem Fab | Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor. |
US6806257B1 (en) | 1999-10-20 | 2004-10-19 | Board Of Trustees Of Southern Illinois University | Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators |
US6334998B1 (en) * | 1999-12-07 | 2002-01-01 | Parker Hughes Institute | Estrogens for treating ALS |
EP1127572A3 (en) * | 2000-02-25 | 2003-05-02 | Basf Aktiengesellschaft | Use of flavones for treating cycloxygenase-2 mediated diseases |
US6472436B1 (en) * | 2000-07-17 | 2002-10-29 | The Salk Institute For Biological Studies | Methods for protecting cells from amyloid toxicity and for inhibiting amyloid protein production |
DE10104350A1 (de) * | 2001-02-01 | 2002-08-14 | Merck Patent Gmbh | Verfahren zur Herstellung von Flavon Derivaten |
DE10232595A1 (de) * | 2002-07-18 | 2004-02-05 | Merck Patent Gmbh | Lichtschutzmittel |
EA200501548A1 (ru) | 2003-04-01 | 2006-02-24 | Апплайд Резеч Системз Арс Холдинг Н.В. | Ингибиторы фосфодиэстераз при бесплодии |
JP5058481B2 (ja) * | 2005-11-28 | 2012-10-24 | 丸善製薬株式会社 | 角化細胞増殖剤、サイクリックampホスホジエステラーゼ阻害剤、及び保湿剤 |
US20100056791A1 (en) * | 2006-09-01 | 2010-03-04 | Yasushi Kohno | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same |
CN101148444A (zh) * | 2006-09-20 | 2008-03-26 | 上海特化医药科技有限公司 | 黄酮衍生物、制备方法及应用 |
KR100930467B1 (ko) | 2007-06-07 | 2009-12-08 | 동아제약주식회사 | 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도 |
JP4559531B1 (ja) * | 2009-12-03 | 2010-10-06 | ウシオケミックス株式会社 | ノビレチンの製造方法 |
CN103059005B (zh) * | 2012-11-22 | 2015-04-22 | 中南民族大学 | 白杨素酰胺衍生物及其医药用途 |
CN105906598B (zh) * | 2016-05-19 | 2018-05-08 | 江苏耐雀生物工程技术有限公司 | 白杨素衍生物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2623808B1 (fr) * | 1987-12-01 | 1990-03-09 | Adir | Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
FR2689127B1 (fr) * | 1992-03-31 | 1994-05-06 | Adir Cie | Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
FR2748025B1 (fr) * | 1996-04-25 | 1998-10-30 | Adir | Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant |
-
1996
- 1996-09-27 FR FR9611808A patent/FR2753969B1/fr not_active Expired - Fee Related
-
1997
- 1997-09-23 EP EP97402202A patent/EP0832886B1/fr not_active Expired - Lifetime
- 1997-09-23 DE DE69717044T patent/DE69717044T2/de not_active Expired - Fee Related
- 1997-09-23 DK DK97402202T patent/DK0832886T3/da active
- 1997-09-23 PT PT97402202T patent/PT832886E/pt unknown
- 1997-09-23 ES ES97402202T patent/ES2187738T3/es not_active Expired - Lifetime
- 1997-09-23 AT AT97402202T patent/ATE227712T1/de not_active IP Right Cessation
- 1997-09-25 PL PL97322297A patent/PL322297A1/xx unknown
- 1997-09-26 NZ NZ328858A patent/NZ328858A/en unknown
- 1997-09-26 BR BR9704900A patent/BR9704900A/pt not_active IP Right Cessation
- 1997-09-26 ZA ZA9708652A patent/ZA978652B/xx unknown
- 1997-09-26 CA CA002216617A patent/CA2216617C/fr not_active Expired - Fee Related
- 1997-09-26 AU AU39271/97A patent/AU728990B2/en not_active Ceased
- 1997-09-26 JP JP9261323A patent/JPH10114766A/ja active Pending
- 1997-09-26 US US08/968,837 patent/US5889003A/en not_active Expired - Fee Related
- 1997-09-26 NO NO974455A patent/NO974455L/no not_active Application Discontinuation
- 1997-09-26 HU HU9701588A patent/HUP9701588A3/hu unknown
- 1997-09-26 CN CN97120535A patent/CN1094936C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1094936C (zh) | 2002-11-27 |
DE69717044T2 (de) | 2003-07-24 |
EP0832886A1 (fr) | 1998-04-01 |
CA2216617C (fr) | 2002-12-03 |
DE69717044D1 (de) | 2002-12-19 |
HUP9701588A2 (hu) | 1998-12-28 |
HU9701588D0 (en) | 1997-11-28 |
FR2753969A1 (fr) | 1998-04-03 |
NO974455D0 (no) | 1997-09-26 |
DK0832886T3 (da) | 2003-03-10 |
FR2753969B1 (fr) | 1998-10-30 |
PL322297A1 (en) | 1998-03-30 |
AU728990B2 (en) | 2001-01-25 |
ATE227712T1 (de) | 2002-11-15 |
AU3927197A (en) | 1998-04-02 |
NO974455L (no) | 1998-03-30 |
PT832886E (pt) | 2003-03-31 |
CN1179422A (zh) | 1998-04-22 |
CA2216617A1 (fr) | 1998-03-27 |
US5889003A (en) | 1999-03-30 |
JPH10114766A (ja) | 1998-05-06 |
NZ328858A (en) | 1998-01-26 |
EP0832886B1 (fr) | 2002-11-13 |
BR9704900A (pt) | 1998-10-27 |
HUP9701588A3 (en) | 1999-03-01 |
ES2187738T3 (es) | 2003-06-16 |
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