BR9704900A - Compostos de vlavona processo para a sua preparação e composições farmacêuticas contendo os mesmos - Google Patents

Compostos de vlavona processo para a sua preparação e composições farmacêuticas contendo os mesmos

Info

Publication number
BR9704900A
BR9704900A BR9704900A BR9704900A BR9704900A BR 9704900 A BR9704900 A BR 9704900A BR 9704900 A BR9704900 A BR 9704900A BR 9704900 A BR9704900 A BR 9704900A BR 9704900 A BR9704900 A BR 9704900A
Authority
BR
Brazil
Prior art keywords
alkyl
optionally substituted
alkoxy
optionally
aryl
Prior art date
Application number
BR9704900A
Other languages
English (en)
Inventor
Guy Lewin
Alain Dhainaut
Emmanuel Canet
Yves Rolland
Michel Lonchampt
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of BR9704900A publication Critical patent/BR9704900A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR9704900A 1996-09-27 1997-09-26 Compostos de vlavona processo para a sua preparação e composições farmacêuticas contendo os mesmos BR9704900A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611808A FR2753969B1 (fr) 1996-09-27 1996-09-27 Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR9704900A true BR9704900A (pt) 1998-10-27

Family

ID=9496129

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9704900A BR9704900A (pt) 1996-09-27 1997-09-26 Compostos de vlavona processo para a sua preparação e composições farmacêuticas contendo os mesmos

Country Status (18)

Country Link
US (1) US5889003A (pt)
EP (1) EP0832886B1 (pt)
JP (1) JPH10114766A (pt)
CN (1) CN1094936C (pt)
AT (1) ATE227712T1 (pt)
AU (1) AU728990B2 (pt)
BR (1) BR9704900A (pt)
CA (1) CA2216617C (pt)
DE (1) DE69717044T2 (pt)
DK (1) DK0832886T3 (pt)
ES (1) ES2187738T3 (pt)
FR (1) FR2753969B1 (pt)
HU (1) HUP9701588A3 (pt)
NO (1) NO974455L (pt)
NZ (1) NZ328858A (pt)
PL (1) PL322297A1 (pt)
PT (1) PT832886E (pt)
ZA (1) ZA978652B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997011692A2 (en) * 1995-09-11 1997-04-03 Osteoarthritis Sciences, Inc. Protein tyrosine kinase inhibitors for treating osteoarthritis
WO2000012078A1 (en) 1998-08-26 2000-03-09 Smithkline Beecham Corporation Therapies for treating pulmonary diseases
KR20010079922A (ko) * 1998-09-24 2001-08-22 미우라 아키라 하이드록시플라본 유도체
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
US6806257B1 (en) 1999-10-20 2004-10-19 Board Of Trustees Of Southern Illinois University Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators
US6334998B1 (en) * 1999-12-07 2002-01-01 Parker Hughes Institute Estrogens for treating ALS
EP1127572A3 (en) * 2000-02-25 2003-05-02 Basf Aktiengesellschaft Use of flavones for treating cycloxygenase-2 mediated diseases
US6472436B1 (en) * 2000-07-17 2002-10-29 The Salk Institute For Biological Studies Methods for protecting cells from amyloid toxicity and for inhibiting amyloid protein production
DE10104350A1 (de) * 2001-02-01 2002-08-14 Merck Patent Gmbh Verfahren zur Herstellung von Flavon Derivaten
DE10232595A1 (de) * 2002-07-18 2004-02-05 Merck Patent Gmbh Lichtschutzmittel
AU2004226353A1 (en) 2003-04-01 2004-10-14 Laboratoires Serono Sa Inhibitors of phosphodiesterases in infertility
JP5058481B2 (ja) * 2005-11-28 2012-10-24 丸善製薬株式会社 角化細胞増殖剤、サイクリックampホスホジエステラーゼ阻害剤、及び保湿剤
US20100056791A1 (en) * 2006-09-01 2010-03-04 Yasushi Kohno Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same
CN101148444A (zh) * 2006-09-20 2008-03-26 上海特化医药科技有限公司 黄酮衍生物、制备方法及应用
KR100930467B1 (ko) * 2007-06-07 2009-12-08 동아제약주식회사 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도
JP4559531B1 (ja) * 2009-12-03 2010-10-06 ウシオケミックス株式会社 ノビレチンの製造方法
CN103059005B (zh) * 2012-11-22 2015-04-22 中南民族大学 白杨素酰胺衍生物及其医药用途
CN105906598B (zh) * 2016-05-19 2018-05-08 江苏耐雀生物工程技术有限公司 白杨素衍生物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623808B1 (fr) * 1987-12-01 1990-03-09 Adir Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2748025B1 (fr) * 1996-04-25 1998-10-30 Adir Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
EP0832886B1 (fr) 2002-11-13
HU9701588D0 (en) 1997-11-28
PT832886E (pt) 2003-03-31
US5889003A (en) 1999-03-30
NZ328858A (en) 1998-01-26
FR2753969B1 (fr) 1998-10-30
AU728990B2 (en) 2001-01-25
DK0832886T3 (da) 2003-03-10
CN1179422A (zh) 1998-04-22
ES2187738T3 (es) 2003-06-16
HUP9701588A2 (hu) 1998-12-28
DE69717044D1 (de) 2002-12-19
AU3927197A (en) 1998-04-02
FR2753969A1 (fr) 1998-04-03
NO974455D0 (no) 1997-09-26
DE69717044T2 (de) 2003-07-24
EP0832886A1 (fr) 1998-04-01
HUP9701588A3 (en) 1999-03-01
JPH10114766A (ja) 1998-05-06
CA2216617A1 (fr) 1998-03-27
CA2216617C (fr) 2002-12-03
ATE227712T1 (de) 2002-11-15
CN1094936C (zh) 2002-11-27
NO974455L (no) 1998-03-30
ZA978652B (en) 1998-03-27
PL322297A1 (en) 1998-03-30

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Legal Events

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Free format text: LES LABORATOIRES SERVIER (FR)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1834 DE 01/03/2006.