ZA977544B - Manufacture and pharmaceutical use of pyrimidine compounds - Google Patents

Manufacture and pharmaceutical use of pyrimidine compounds

Info

Publication number
ZA977544B
ZA977544B ZA977544A ZA977544A ZA977544B ZA 977544 B ZA977544 B ZA 977544B ZA 977544 A ZA977544 A ZA 977544A ZA 977544 A ZA977544 A ZA 977544A ZA 977544 B ZA977544 B ZA 977544B
Authority
ZA
South Africa
Prior art keywords
pyrimidine compounds
manufacture
pharmaceutical use
complex
compound
Prior art date
Application number
ZA977544A
Other languages
English (en)
Inventor
Nicholas John Holman
Stefan Koser
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of ZA977544B publication Critical patent/ZA977544B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA977544A 1996-08-23 1997-08-22 Manufacture and pharmaceutical use of pyrimidine compounds ZA977544B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9617727.4A GB9617727D0 (en) 1996-08-23 1996-08-23 Process

Publications (1)

Publication Number Publication Date
ZA977544B true ZA977544B (en) 1999-02-22

Family

ID=10798876

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA977544A ZA977544B (en) 1996-08-23 1997-08-22 Manufacture and pharmaceutical use of pyrimidine compounds

Country Status (18)

Country Link
US (1) US6225469B1 (zh)
EP (1) EP0922046B1 (zh)
JP (1) JP2000514087A (zh)
KR (1) KR20000068324A (zh)
CN (1) CN1080265C (zh)
AT (1) ATE265457T1 (zh)
AU (1) AU739874B2 (zh)
BR (1) BR9711213A (zh)
CA (1) CA2263368A1 (zh)
CZ (1) CZ59599A3 (zh)
DE (1) DE69728887D1 (zh)
GB (1) GB9617727D0 (zh)
IL (1) IL128120A (zh)
IN (1) IN183689B (zh)
NO (1) NO310873B1 (zh)
TW (1) TW494102B (zh)
WO (1) WO1998007724A1 (zh)
ZA (1) ZA977544B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9626746D0 (en) * 1996-12-23 1997-02-12 Knoll Ag Process
GB9906130D0 (en) * 1999-03-18 1999-05-12 Knoll Ag Compounds for use in therapy
GB9906124D0 (en) * 1999-03-18 1999-05-12 Knoll Ag Therapeutic agent
CN106967071A (zh) * 2017-03-24 2017-07-21 福建省微生物研究所 一种依鲁替尼中间体的分离纯化方法
CN109232581A (zh) * 2018-11-28 2019-01-18 福建省微生物研究所 以氯化锌分离纯化依鲁替尼中间体的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4080325A (en) 1976-11-17 1978-03-21 The United States Of America As Represented By The Department Of Health, Education And Welfare Synthesis of methotrexate
US4421913A (en) 1980-04-23 1983-12-20 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Separation of triphenylphosphine oxide from methotrexate ester and purification of said ester
US5177206A (en) 1991-10-08 1993-01-05 Dowelanco Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides
GB9321162D0 (en) * 1993-10-13 1993-12-01 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
US6225469B1 (en) 2001-05-01
EP0922046A1 (en) 1999-06-16
GB9617727D0 (en) 1996-10-02
ATE265457T1 (de) 2004-05-15
AU739874B2 (en) 2001-10-25
AU4205097A (en) 1998-03-06
CA2263368A1 (en) 1998-02-26
NO990822L (no) 1999-04-15
BR9711213A (pt) 1999-08-17
IL128120A0 (en) 1999-11-30
CN1228093A (zh) 1999-09-08
TW494102B (en) 2002-07-11
DE69728887D1 (de) 2004-06-03
KR20000068324A (ko) 2000-11-25
CZ59599A3 (cs) 1999-06-16
CN1080265C (zh) 2002-03-06
IN183689B (zh) 2000-03-18
NO310873B1 (no) 2001-09-10
IL128120A (en) 2001-10-31
MX9901653A (es) 2002-08-20
EP0922046B1 (en) 2004-04-28
WO1998007724A1 (en) 1998-02-26
NO990822D0 (no) 1999-02-22
JP2000514087A (ja) 2000-10-24

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