ZA977087B - Methods of cancer treatment using naaladase inhibitors - Google Patents
Methods of cancer treatment using naaladase inhibitorsInfo
- Publication number
- ZA977087B ZA977087B ZA977087A ZA977087A ZA977087B ZA 977087 B ZA977087 B ZA 977087B ZA 977087 A ZA977087 A ZA 977087A ZA 977087 A ZA977087 A ZA 977087A ZA 977087 B ZA977087 B ZA 977087B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- cancer treatment
- naaladase inhibitors
- naaladase
- inhibitors
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3826—Acyclic unsaturated acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/665,775 US5804602A (en) | 1996-06-17 | 1996-06-17 | Methods of cancer treatment using naaladase inhibitors |
US08/864,545 US6011021A (en) | 1996-06-17 | 1997-05-28 | Methods of cancer treatment using naaladase inhibitors |
CA002257433A CA2257433A1 (fr) | 1996-06-17 | 1997-06-13 | Methodes de traitement du cancer a l'aide d'inhibiteurs de la naaladase |
PCT/US1997/010149 WO1997048409A1 (fr) | 1996-06-17 | 1997-06-13 | Methodes de traitement du cancer a l'aide d'inhibiteurs de la naaladase |
PL97330782A PL330782A1 (en) | 1996-06-17 | 1997-06-13 | Method of treating carcinoma using the inhibitors of naaladase |
BR9709819-1A BR9709819A (pt) | 1996-06-17 | 1997-06-13 | Processo para tratamento decâncer usando inibidores de naaladase |
EP97929944A EP0954295A1 (fr) | 1996-06-17 | 1997-06-13 | Methodes de traitement du cancer a l'aide d'inhibiteurs de la naaladase |
CN97195439A CN1221346A (zh) | 1996-06-17 | 1997-06-13 | 用NAALADase抑制物治疗癌症的方法 |
US08/900,194 US6025345A (en) | 1996-06-17 | 1997-07-25 | Inhibitors of NAALADase enzyme activity |
ZA977087A ZA977087B (en) | 1996-06-17 | 1997-08-08 | Methods of cancer treatment using naaladase inhibitors |
PCT/US1997/014347 WO1998053812A1 (fr) | 1997-05-27 | 1997-08-15 | Inhibiteurs de l'activite enzymatique de naaladase |
EP97937265A EP0994707A4 (fr) | 1997-05-27 | 1997-08-15 | Inhibiteurs de l'activite enzymatique de naaladase |
NO985652A NO985652L (no) | 1996-06-17 | 1998-12-03 | Anvendelse av naaladaseinhibitorer ved behandling av kreft |
LVP-98-279A LV12253B (lv) | 1996-06-17 | 1999-02-11 | Naaladāzes inhibitori un to pielietojums vēža ārstēšanai |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/665,775 US5804602A (en) | 1996-06-17 | 1996-06-17 | Methods of cancer treatment using naaladase inhibitors |
US08/864,545 US6011021A (en) | 1996-06-17 | 1997-05-28 | Methods of cancer treatment using naaladase inhibitors |
ZA977087A ZA977087B (en) | 1996-06-17 | 1997-08-08 | Methods of cancer treatment using naaladase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA977087B true ZA977087B (en) | 1999-06-30 |
Family
ID=27418138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA977087A ZA977087B (en) | 1996-06-17 | 1997-08-08 | Methods of cancer treatment using naaladase inhibitors |
Country Status (10)
Country | Link |
---|---|
US (1) | US6011021A (fr) |
EP (1) | EP0954295A1 (fr) |
CN (1) | CN1221346A (fr) |
BR (1) | BR9709819A (fr) |
CA (1) | CA2257433A1 (fr) |
LV (1) | LV12253B (fr) |
NO (1) | NO985652L (fr) |
PL (1) | PL330782A1 (fr) |
WO (1) | WO1997048409A1 (fr) |
ZA (1) | ZA977087B (fr) |
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DE69635801T2 (de) | 1995-02-24 | 2006-11-02 | Sloan-Kettering Institute For Cancer Research | Prostataspezifisches membranes antigen und seine anwendungen |
US20040253246A1 (en) * | 1996-02-23 | 2004-12-16 | Israeli Ron S. | Prostate-specific membrane antigen and uses thereof |
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EP1177200B1 (fr) | 1999-04-28 | 2005-06-22 | Georgetown University | Ligands pour recepteurs metabotropes du glutamate |
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EP1443954B1 (fr) * | 2001-10-26 | 2010-11-24 | The Scripps Research Institute | Thrombose cible par de polypeptides du facteur tissulaire |
US7148250B2 (en) | 2001-12-28 | 2006-12-12 | Guilford Pharmaceuticals Inc. | Indoles as NAALADase inhibitors |
CN1332964C (zh) * | 2002-03-21 | 2007-08-22 | 舍林股份公司 | 血浆羧肽酶b抑制剂 |
EP1599461B1 (fr) * | 2003-03-03 | 2009-06-10 | Eisai Corporation of North America | THIOLACTONES COMME INHIBITEURS DE LA NAALADase |
CN101084231B (zh) * | 2004-09-17 | 2011-08-24 | 埃迪尼克斯医药公司 | 作为hiv抑制剂的磷酸-吲哚 |
SI1799696T1 (sl) | 2004-09-17 | 2009-04-30 | Idenix Pharmaceuticals Inc | Fosfoindoli kot hiv inhibitorji |
EP1874322A1 (fr) * | 2005-04-18 | 2008-01-09 | Bayer Schering Pharma Aktiengesellschaft | Utilisation d'inhibiteurs de tafi pour ameliorer la reperfusion myocardique et faciliter la pci |
CA2664396A1 (fr) | 2006-09-29 | 2008-04-10 | Idenix Pharmaceuticals, Inc. | Phosphoindoles enantiomeriquement purs utilisables en tant qu'inhibiteurs du vih |
CN101778910B (zh) | 2006-11-08 | 2014-05-28 | 分子制药洞察公司 | 谷氨酸的异质二聚体 |
JP2010510314A (ja) | 2006-11-22 | 2010-04-02 | シーサイド セラピューティクス,エルエルシー | 精神遅滞、ダウン症候群、脆弱x症候群および自閉症の治療方法 |
WO2010065899A2 (fr) | 2008-12-05 | 2010-06-10 | Molecular Insight Pharmaceuticals, Inc. | Complexes de technétium- et rhénium-bis (hétéroaryles) et leurs procédés d'utilisation |
JP5690286B2 (ja) | 2009-03-04 | 2015-03-25 | イデニク プハルマセウティカルス,インコーポレイテッド | ホスホチオフェン及びホスホチアゾールhcvポリメラーゼ阻害剤 |
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CN102917699A (zh) | 2009-10-13 | 2013-02-06 | 密执安大学评议会 | 树枝状聚合物组合物和合成方法 |
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WO2013103813A1 (fr) | 2012-01-06 | 2013-07-11 | Molecular Insight Pharmaceuticals | Complexe métalliques de poly (carboxyl) amine contenant des ligands ayant une affinité pour l'anhydrase carbonique ix |
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JP2632754B2 (ja) * | 1991-05-21 | 1997-07-23 | 塩野義製薬株式会社 | 脳内グルタミン酸遊離抑制剤 |
DE4141928A1 (de) * | 1991-12-19 | 1993-06-24 | Boehringer Mannheim Gmbh | Neue phosphonobernsteinsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
US5326856A (en) * | 1992-04-09 | 1994-07-05 | Cytogen Corporation | Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding |
USH1312H (en) * | 1992-05-28 | 1994-05-03 | Cytogen Corporation | Method for the preparation of gyk-dtpa |
US5489525A (en) * | 1992-10-08 | 1996-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies to prostate cells |
PT668777E (pt) * | 1992-11-05 | 2007-01-31 | Sloan Kettering Inst Cancer | Antigenio de membrana especifico para a prostata |
US5449761A (en) * | 1993-09-28 | 1995-09-12 | Cytogen Corporation | Metal-binding targeted polypeptide constructs |
US5495042A (en) * | 1993-11-04 | 1996-02-27 | Cytogen Corporation | Non-alkaline purification of aminophosphonic acids |
US5500420A (en) * | 1993-12-20 | 1996-03-19 | Cornell Research Foundation, Inc. | Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia |
US5508273A (en) * | 1993-12-30 | 1996-04-16 | Ortho Pharmaceutical Corporation | Substituted phosphonic acids and derivatives useful in treating bone wasting diseases |
US5698402A (en) * | 1995-02-23 | 1997-12-16 | Dianon Systems, Inc. | Methods for diagnosing benign prostatic hyperplasia |
US5672592A (en) * | 1996-06-17 | 1997-09-30 | Guilford Pharmaceuticals Inc. | Certain phosphonomethyl-pentanedioic acid derivatives thereof |
-
1997
- 1997-05-28 US US08/864,545 patent/US6011021A/en not_active Expired - Fee Related
- 1997-06-13 CA CA002257433A patent/CA2257433A1/fr not_active Abandoned
- 1997-06-13 EP EP97929944A patent/EP0954295A1/fr not_active Withdrawn
- 1997-06-13 CN CN97195439A patent/CN1221346A/zh active Pending
- 1997-06-13 BR BR9709819-1A patent/BR9709819A/pt not_active IP Right Cessation
- 1997-06-13 PL PL97330782A patent/PL330782A1/xx unknown
- 1997-06-13 WO PCT/US1997/010149 patent/WO1997048409A1/fr not_active Application Discontinuation
- 1997-08-08 ZA ZA977087A patent/ZA977087B/xx unknown
-
1998
- 1998-12-03 NO NO985652A patent/NO985652L/no not_active Application Discontinuation
-
1999
- 1999-02-11 LV LVP-98-279A patent/LV12253B/lv unknown
Also Published As
Publication number | Publication date |
---|---|
US6011021A (en) | 2000-01-04 |
NO985652D0 (no) | 1998-12-03 |
LV12253B (lv) | 2000-01-20 |
CA2257433A1 (fr) | 1997-12-04 |
CN1221346A (zh) | 1999-06-30 |
NO985652L (no) | 1999-02-09 |
LV12253A (lv) | 1999-04-20 |
WO1997048409A1 (fr) | 1997-12-24 |
BR9709819A (pt) | 2000-01-11 |
EP0954295A1 (fr) | 1999-11-10 |
PL330782A1 (en) | 1999-06-07 |
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