ZA975764B - Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS) - Google Patents
Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS)Info
- Publication number
- ZA975764B ZA975764B ZA975764A ZA975764A ZA975764B ZA 975764 B ZA975764 B ZA 975764B ZA 975764 A ZA975764 A ZA 975764A ZA 975764 A ZA975764 A ZA 975764A ZA 975764 B ZA975764 B ZA 975764B
- Authority
- ZA
- South Africa
- Prior art keywords
- als
- lateral sclerosis
- amyotrophic lateral
- derivatives useful
- treating amyotrophic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2200696P | 1996-06-28 | 1996-06-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA975764B true ZA975764B (en) | 1998-12-28 |
Family
ID=21807346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA975764A ZA975764B (en) | 1996-06-28 | 1997-06-27 | Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS) |
Country Status (22)
Country | Link |
---|---|
US (1) | US5753694A (xx) |
EP (1) | EP0936908B1 (xx) |
JP (1) | JP2000514426A (xx) |
AP (1) | AP1167A (xx) |
AT (1) | ATE214274T1 (xx) |
AU (1) | AU725093B2 (xx) |
BR (1) | BR9710993A (xx) |
CA (1) | CA2258892C (xx) |
CZ (1) | CZ293945B6 (xx) |
DE (1) | DE69711067T2 (xx) |
DK (1) | DK0936908T3 (xx) |
ES (1) | ES2176755T3 (xx) |
HU (1) | HUP9904318A3 (xx) |
IL (1) | IL127717A (xx) |
NO (1) | NO317136B1 (xx) |
NZ (1) | NZ333588A (xx) |
PT (1) | PT936908E (xx) |
SI (1) | SI0936908T1 (xx) |
SK (1) | SK284331B6 (xx) |
UA (1) | UA46112C2 (xx) |
WO (1) | WO1998000131A1 (xx) |
ZA (1) | ZA975764B (xx) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5985930A (en) * | 1996-11-21 | 1999-11-16 | Pasinetti; Giulio M. | Treatment of neurodegenerative conditions with nimesulide |
WO2000061138A1 (en) * | 1999-04-08 | 2000-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders |
US7659256B2 (en) * | 1999-06-14 | 2010-02-09 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
DE60035870T2 (de) | 1999-06-14 | 2008-05-08 | Vivus Inc., Mountain View | Kombinationstherapie zur gewichtsreduzierung und fettleibigkeitsbehandlung |
US20080103179A1 (en) * | 2006-10-27 | 2008-05-01 | Tam Peter Y | Combination Therapy |
US7553818B2 (en) * | 1999-06-14 | 2009-06-30 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
US7674776B2 (en) | 1999-06-14 | 2010-03-09 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
US20080255093A1 (en) * | 1999-06-14 | 2008-10-16 | Tam Peter Y | Compositions and methods for treating obesity and related disorders |
US7056890B2 (en) | 1999-06-14 | 2006-06-06 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
US6191117B1 (en) * | 2000-07-10 | 2001-02-20 | Walter E. Kozachuk | Methods of producing weight loss and treatment of obesity |
WO2002043731A2 (en) | 2000-11-30 | 2002-06-06 | University Of Florida | Treatments for neurogenetic disorders, impulse control disorders, and wound healing |
WO2002064085A2 (en) * | 2001-02-02 | 2002-08-22 | Ortho-Mcneil Pharmaceutical, Inc. | Treatment of neurological dysfunction comprising fructopyranose sulfamates and erythropoietin |
JP2005514352A (ja) * | 2001-11-14 | 2005-05-19 | ラルフ ライバック | 自己免疫疾患の治療法 |
US20060041022A1 (en) * | 2002-11-06 | 2006-02-23 | Pasinetti Giulio M | Treatment of amyotrophic lateral sclerosis with nimesulide |
CA2505514A1 (en) * | 2002-11-06 | 2004-05-27 | Mount Sinai School Of Medicine | Treatment of amyotrophic lateral sclerosis with nimesulide |
US20050070524A1 (en) * | 2003-06-06 | 2005-03-31 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders |
TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MX2007002309A (es) * | 2004-08-24 | 2007-10-08 | Johnson & Johnson | Novedosos derivados de heteroarilsulfamida benzofusionados utiles como agentes anticonvulsivos. |
IS7748A (is) * | 2005-03-17 | 2006-09-18 | Actavis Group | Samsetning fyrir töflur sem innihalda topiramate |
JP2008545650A (ja) * | 2005-05-20 | 2008-12-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | スルファミド誘導体の製造方法 |
US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
US8492431B2 (en) * | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
US20070191451A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives as neuroprotective agents |
US20070191460A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Disease Modification / Epileptogenesis |
US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
EP2026790A2 (en) * | 2006-05-19 | 2009-02-25 | Janssen Pharmaceutica, N.V. | Co-therapy for the treatment of epilepsy and related disorders |
FR2903019A1 (fr) * | 2006-06-30 | 2008-01-04 | Univ Claude Bernard Lyon I Eta | Utilisation d'un inhibiteur de l'anhydrase carbonique, pour la preparation d'un medicament destine a traiter des degenerescences du muscle squelettique |
US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
US20090304789A1 (en) * | 2008-06-09 | 2009-12-10 | Thomas Najarian | Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders |
US8580298B2 (en) | 2008-06-09 | 2013-11-12 | Vivus, Inc. | Low dose topiramate/phentermine composition and methods of use thereof |
EA018567B1 (ru) | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
US4792569A (en) * | 1987-08-27 | 1988-12-20 | Mcneilab, Inc. | Anticonvulsant phenethyl sulfamates |
US5384327A (en) * | 1992-12-22 | 1995-01-24 | Mcneilab, Inc. | Anticonvulsant sorbopyranose sulfamates |
-
1997
- 1997-06-23 US US08/881,023 patent/US5753694A/en not_active Expired - Fee Related
- 1997-06-24 JP JP10504245A patent/JP2000514426A/ja active Pending
- 1997-06-24 ES ES97931367T patent/ES2176755T3/es not_active Expired - Lifetime
- 1997-06-24 NZ NZ333588A patent/NZ333588A/xx unknown
- 1997-06-24 DE DE69711067T patent/DE69711067T2/de not_active Expired - Fee Related
- 1997-06-24 SK SK1806-98A patent/SK284331B6/sk unknown
- 1997-06-24 CA CA002258892A patent/CA2258892C/en not_active Expired - Fee Related
- 1997-06-24 DK DK97931367T patent/DK0936908T3/da active
- 1997-06-24 AP APAP/P/1998/001428A patent/AP1167A/en active
- 1997-06-24 PT PT97931367T patent/PT936908E/pt unknown
- 1997-06-24 EP EP97931367A patent/EP0936908B1/en not_active Expired - Lifetime
- 1997-06-24 UA UA98126945A patent/UA46112C2/uk unknown
- 1997-06-24 AT AT97931367T patent/ATE214274T1/de not_active IP Right Cessation
- 1997-06-24 HU HU9904318A patent/HUP9904318A3/hu unknown
- 1997-06-24 IL IL12771797A patent/IL127717A/en not_active IP Right Cessation
- 1997-06-24 CZ CZ19984279A patent/CZ293945B6/cs not_active IP Right Cessation
- 1997-06-24 SI SI9730259T patent/SI0936908T1/xx unknown
- 1997-06-24 BR BR9710993-2A patent/BR9710993A/pt not_active Application Discontinuation
- 1997-06-24 WO PCT/US1997/010955 patent/WO1998000131A1/en active IP Right Grant
- 1997-06-24 AU AU35010/97A patent/AU725093B2/en not_active Ceased
- 1997-06-27 ZA ZA975764A patent/ZA975764B/xx unknown
-
1998
- 1998-12-22 NO NO19986054A patent/NO317136B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
DK0936908T3 (da) | 2002-05-27 |
SK180698A3 (en) | 2000-07-11 |
ES2176755T3 (es) | 2002-12-01 |
NZ333588A (en) | 2000-07-28 |
AP9801428A0 (en) | 1998-12-31 |
CZ293945B6 (cs) | 2004-08-18 |
NO986054D0 (no) | 1998-12-22 |
BR9710993A (pt) | 2002-02-26 |
HUP9904318A2 (hu) | 2000-05-28 |
IL127717A (en) | 2004-09-27 |
IL127717A0 (en) | 1999-10-28 |
PT936908E (pt) | 2002-08-30 |
CZ427998A3 (cs) | 1999-08-11 |
NO986054L (no) | 1999-03-01 |
US5753694A (en) | 1998-05-19 |
HUP9904318A3 (en) | 2001-02-28 |
AU725093B2 (en) | 2000-10-05 |
UA46112C2 (uk) | 2002-05-15 |
JP2000514426A (ja) | 2000-10-31 |
AP1167A (en) | 2003-06-30 |
AU3501097A (en) | 1998-01-21 |
CA2258892A1 (en) | 1998-01-08 |
EP0936908A1 (en) | 1999-08-25 |
SK284331B6 (sk) | 2005-01-03 |
DE69711067T2 (de) | 2002-09-19 |
SI0936908T1 (en) | 2002-12-31 |
WO1998000131A1 (en) | 1998-01-08 |
NO317136B1 (no) | 2004-08-23 |
CA2258892C (en) | 2005-08-09 |
DE69711067D1 (de) | 2002-04-18 |
ATE214274T1 (de) | 2002-03-15 |
EP0936908B1 (en) | 2002-03-13 |
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