ZA972673B - Process for the production of intermediate compounds for the production of factor Xa inhibitors - Google Patents

Process for the production of intermediate compounds for the production of factor Xa inhibitors

Info

Publication number
ZA972673B
ZA972673B ZA972673A ZA972673A ZA972673B ZA 972673 B ZA972673 B ZA 972673B ZA 972673 A ZA972673 A ZA 972673A ZA 972673 A ZA972673 A ZA 972673A ZA 972673 B ZA972673 B ZA 972673B
Authority
ZA
South Africa
Prior art keywords
production
inhibitors
factor
intermediate compounds
compounds
Prior art date
Application number
ZA972673A
Other languages
English (en)
Inventor
Wolfgang Von Der Saal
Ralf Kucznierz
Herbert Leinert
Richard Neidlein
Christiane Kehr
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA972673B publication Critical patent/ZA972673B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/52—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of six-membered aromatic rings being part of condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA972673A 1996-03-30 1997-03-27 Process for the production of intermediate compounds for the production of factor Xa inhibitors ZA972673B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19612828A DE19612828C1 (de) 1996-03-30 1996-03-30 Verfahren zur Herstellung von Naphthonitrilderivaten und deren Verwendung zur Herstellung von Faktor-Xa-Inhibitoren

Publications (1)

Publication Number Publication Date
ZA972673B true ZA972673B (en) 1998-09-28

Family

ID=7790037

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA972673A ZA972673B (en) 1996-03-30 1997-03-27 Process for the production of intermediate compounds for the production of factor Xa inhibitors

Country Status (4)

Country Link
AU (1) AU2159997A (xx)
DE (1) DE19612828C1 (xx)
WO (1) WO1997036865A1 (xx)
ZA (1) ZA972673B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003302238A1 (en) 2002-12-03 2004-06-23 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
CN102503763A (zh) * 2011-11-28 2012-06-20 上海工程技术大学 二苯乙烯类化合物的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.

Also Published As

Publication number Publication date
DE19612828C1 (de) 1997-02-27
WO1997036865A1 (de) 1997-10-09
AU2159997A (en) 1997-10-22

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