ZA972673B - Process for the production of intermediate compounds for the production of factor Xa inhibitors - Google Patents

Process for the production of intermediate compounds for the production of factor Xa inhibitors

Info

Publication number
ZA972673B
ZA972673B ZA972673A ZA972673A ZA972673B ZA 972673 B ZA972673 B ZA 972673B ZA 972673 A ZA972673 A ZA 972673A ZA 972673 A ZA972673 A ZA 972673A ZA 972673 B ZA972673 B ZA 972673B
Authority
ZA
South Africa
Prior art keywords
production
inhibitors
factor
intermediate compounds
compounds
Prior art date
Application number
ZA972673A
Inventor
Wolfgang Von Der Saal
Ralf Kucznierz
Herbert Leinert
Richard Neidlein
Christiane Kehr
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA972673B publication Critical patent/ZA972673B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/52Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of six-membered aromatic rings being part of condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA972673A 1996-03-30 1997-03-27 Process for the production of intermediate compounds for the production of factor Xa inhibitors ZA972673B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19612828A DE19612828C1 (en) 1996-03-30 1996-03-30 Cyano-naphthyl-substd. phenyl-ethene or -acrylic acid derivs. prodn.

Publications (1)

Publication Number Publication Date
ZA972673B true ZA972673B (en) 1998-09-28

Family

ID=7790037

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA972673A ZA972673B (en) 1996-03-30 1997-03-27 Process for the production of intermediate compounds for the production of factor Xa inhibitors

Country Status (4)

Country Link
AU (1) AU2159997A (en)
DE (1) DE19612828C1 (en)
WO (1) WO1997036865A1 (en)
ZA (1) ZA972673B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1569912T3 (en) 2002-12-03 2015-06-29 Pharmacyclics Inc 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors.
CN102503763A (en) * 2011-11-28 2012-06-20 上海工程技术大学 Preparation method of diphenyl ethylene compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.

Also Published As

Publication number Publication date
WO1997036865A1 (en) 1997-10-09
DE19612828C1 (en) 1997-02-27
AU2159997A (en) 1997-10-22

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