ZA972505B - Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation - Google Patents

Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation

Info

Publication number
ZA972505B
ZA972505B ZA972505A ZA972505A ZA972505B ZA 972505 B ZA972505 B ZA 972505B ZA 972505 A ZA972505 A ZA 972505A ZA 972505 A ZA972505 A ZA 972505A ZA 972505 B ZA972505 B ZA 972505B
Authority
ZA
South Africa
Prior art keywords
liposomes
lipid
manufacture
thin film
protein complexes
Prior art date
Application number
ZA972505A
Other languages
English (en)
Inventor
Robert J Klimchak
Peter G Glavinos Jr
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of ZA972505B publication Critical patent/ZA972505B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA972505A 1996-03-27 1997-03-24 Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation ZA972505B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1422796P 1996-03-27 1996-03-27

Publications (1)

Publication Number Publication Date
ZA972505B true ZA972505B (en) 1998-09-25

Family

ID=21764227

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA972505A ZA972505B (en) 1996-03-27 1997-03-24 Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation

Country Status (4)

Country Link
US (1) US6120795A (fr)
AU (1) AU2066897A (fr)
WO (1) WO1997035559A2 (fr)
ZA (1) ZA972505B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001258117A1 (en) * 2000-05-08 2001-11-20 The University Of British Columbia Supports for photosensitizer formulations
JP2005525375A (ja) * 2002-03-05 2005-08-25 トランセイブ， インク． 生物活性物質をリポソーム又は脂質複合体内に封入する方法
EA200501285A1 (ru) * 2003-02-11 2006-02-24 Неофарм, Инк. Способ получения липосомальных препаратов
EP1830813A2 (fr) * 2004-12-14 2007-09-12 Transave, Inc. Particules lipidiques comprenant des agents bioactifs, procedes de preparation et utilisation
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
HUE032584T2 (en) 2006-02-08 2017-09-28 Morphotek Inc Antigen GM-CSF peptides and GM-CSF antibodies
WO2013188016A2 (fr) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Thérapie utilisant des surfactants pour exposition à un rayonnement ionisant
CN113171694B (zh) 2015-03-19 2023-04-18 康涅狄格大学 用于连续制造脂质体药物制剂的系统和方法
CN106732220B (zh) * 2017-01-03 2019-06-07 江南大学 一种提高脂质体高离子强度下稳定性的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405652A (en) * 1982-01-21 1983-09-20 Joseph E. Seagram & Sons, Inc. Preparation of wine having a low calorie content and a reduced alcohol content
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4902466A (en) * 1986-12-11 1990-02-20 Ciba Corning Diagnostics Corp. Process for making lipid films suitable for liposomes
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US4935171A (en) * 1989-01-27 1990-06-19 Vestar, Inc. Method for vesicle formation
US5028297A (en) * 1989-01-27 1991-07-02 Vestar, Inc. Film-forming evaporation apparatus
US5549910A (en) * 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
US5277914A (en) * 1989-03-31 1994-01-11 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
DE4013580A1 (de) * 1990-04-24 1991-10-31 Schering Ag Verfahren zur herstellung von wirkstoffhaltigen waessrigen liposomensuspensionen
WO1992006703A1 (fr) * 1990-10-17 1992-04-30 The Liposome Company, Inc. Agent tensio-actif synthetique pour le traitement des poumons
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
DE69620801T2 (de) * 1995-11-20 2002-10-10 Ortho Mcneil Pharm Inc Verfahren zur solubisierung des pulmonnären oberflächeraktiven peptides

Also Published As

Publication number Publication date
US6120795A (en) 2000-09-19
WO1997035559A2 (fr) 1997-10-02
AU2066897A (en) 1997-10-17
WO1997035559A3 (fr) 1997-11-20

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