AU2223495A - Spiro compound and medicinal composition thereof - Google Patents

Spiro compound and medicinal composition thereof

Info

Publication number
AU2223495A
AU2223495A AU22234/95A AU2223495A AU2223495A AU 2223495 A AU2223495 A AU 2223495A AU 22234/95 A AU22234/95 A AU 22234/95A AU 2223495 A AU2223495 A AU 2223495A AU 2223495 A AU2223495 A AU 2223495A
Authority
AU
Australia
Prior art keywords
medicinal composition
spiro compound
spiro
compound
medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22234/95A
Inventor
Masahiro Fujii
Ken Ikeda
Yasuo Isomura
Akio Kakefuda
Hirokazu Kubota
Hitoshi Nagaoka
Yoshinori Okamoto
Osamu Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of AU2223495A publication Critical patent/AU2223495A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU22234/95A 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof Abandoned AU2223495A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP6-101936 1994-04-15
JP10193694 1994-04-15
JP25538294 1994-10-20
JP6-255382 1994-10-20
PCT/JP1995/000713 WO1995028389A1 (en) 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof

Publications (1)

Publication Number Publication Date
AU2223495A true AU2223495A (en) 1995-11-10

Family

ID=26442705

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22234/95A Abandoned AU2223495A (en) 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof

Country Status (2)

Country Link
AU (1) AU2223495A (en)
WO (1) WO1995028389A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU224225B1 (en) * 1995-12-01 2005-06-28 Sankyo Co. Ltd. Heterocyclic compounds having tachykinin receptor antagonist activity, their preparation, and their use for the preparation of pharmaceutical compositions
AU732384B2 (en) * 1997-05-30 2001-04-26 Sankyo Company Limited Salts of an optically-active sulfoxide derivative
WO1999021823A1 (en) * 1997-10-27 1999-05-06 Schering Corporation Optically active intermediates for the preparation of optically active substituted oximes, hydrazones and olefins useful as neurokinin antagonists
US6265614B1 (en) 1997-10-27 2001-07-24 Schering Corporation Optically active intermediates for the preparation of optically active substituted oximes, hydrazones and olefins useful as neurokinin antagonists
ATE297906T1 (en) * 1997-12-04 2005-07-15 Sankyo Co ALICYCLIC ACYLATED HETEROCYCLE DERIVATIVES
EP1695977A3 (en) * 2000-12-12 2006-09-20 Neurogen Corporation Spiro [isobenzofuran-1,4'piperidin]-3-ones and 3H-spiroisobenzofuran-1, 4'-piperidines
MXPA03004245A (en) * 2000-12-12 2003-09-22 Neurogen Corp Spiro[isobenzofuran-1,4 -piperidin]-3-ones and 3h-spiroisobenzofuran-1, 4 -piperidines.
AU2002242996A1 (en) * 2001-03-29 2002-10-15 Tanabe Seiyaku Co., Ltd. Spiroisoquinoline compounds, methods for their preparation and intermediates
US20030078278A1 (en) * 2001-06-26 2003-04-24 Pfizer Inc. Spiropiperidine compounds as ligands for ORL-1 receptor
US7396930B2 (en) 2002-06-11 2008-07-08 Sankyo Company, Limited Process for producing cyclic thioether and synthetic intermediate thereof
AU2003296992A1 (en) * 2002-12-13 2004-07-09 Smithkline Beecham Corporation Pyrrolidine and azetidine compounds as ccr5 antagonists
EP1781288A2 (en) 2004-08-19 2007-05-09 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
US7786141B2 (en) 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
RU2007124373A (en) 2004-11-29 2009-01-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) MUSCARINE RECEPTION MODULATORS
JP4769464B2 (en) * 2005-01-12 2011-09-07 広栄化学工業株式会社 Method for producing alcohol compound
JP4371164B2 (en) 2005-11-10 2009-11-25 萬有製薬株式会社 Aza-substituted spiro derivatives
EP1973543A2 (en) 2005-12-22 2008-10-01 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
US8263605B2 (en) 2006-02-22 2012-09-11 Vertex Pharmaceutical Incorporated Modulators of muscarinic receptors
RU2008137593A (en) 2006-02-22 2010-03-27 Вертекс Фармасьютикалз Инкорпорейтед (Us) MUSCARINE RECEPTOR MODULATORS
CN101500565A (en) 2006-06-29 2009-08-05 弗特克斯药品有限公司 Modulators of muscarinic receptors
CA2660903A1 (en) 2006-08-15 2008-02-21 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
AU2007284350A1 (en) 2006-08-18 2008-02-21 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
KR20090112722A (en) 2007-01-24 2009-10-28 글락소 그룹 리미티드 Pharmaceutical compositions comprising 3,5-diamino-6-2,3-dichl0rophenyl-1,2,4-triazine or r--2,4-diamino-5-2,3-dichlorophenyl-6-fluoromethyl pyrimidine and an nk1
CA2700724A1 (en) 2007-10-03 2009-04-09 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
BR112012010752B1 (en) 2009-11-05 2021-07-20 University Of Notre Dame Du Lac IMIDAZO[1,2-A]PYRIDINE COMPOUNDS
ES2748694T3 (en) * 2014-11-21 2020-03-17 Esteve Pharmaceuticals Sa Spiroisoquinolin-1,4'-piperidine compounds with multimodal pain relief
AU2016324598A1 (en) 2015-09-17 2018-03-15 Marvin J. Miller Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962259A (en) * 1973-12-12 1976-06-08 American Hoechst Corporation 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof
ES468860A1 (en) * 1977-04-21 1979-09-16 Hoechst Ag Spiro(indoline-3,4'-piperidine)s and related compounds
JPS55143980A (en) * 1979-04-27 1980-11-10 Dai Ichi Seiyaku Co Ltd Anti-allergic preparation
GB8917069D0 (en) * 1989-07-26 1989-09-13 Merck Sharp & Dohme Therapeutic agents
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1995028389A1 (en) 1995-10-26

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