ZA971023B - Quinolonecarboxylic acid derivatives or their salts. - Google Patents
Quinolonecarboxylic acid derivatives or their salts.Info
- Publication number
- ZA971023B ZA971023B ZA9701023A ZA971023A ZA971023B ZA 971023 B ZA971023 B ZA 971023B ZA 9701023 A ZA9701023 A ZA 9701023A ZA 971023 A ZA971023 A ZA 971023A ZA 971023 B ZA971023 B ZA 971023B
- Authority
- ZA
- South Africa
- Prior art keywords
- salts
- optionally substituted
- acid derivatives
- halogeno
- lower alkyl
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- XOQQVKDBGLYPGH-UHFFFAOYSA-N 2-oxo-1h-quinoline-3-carboxylic acid Chemical class C1=CC=C2NC(=O)C(C(=O)O)=CC2=C1 XOQQVKDBGLYPGH-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4793696 | 1996-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA971023B true ZA971023B (en) | 1997-09-25 |
Family
ID=12789268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9701023A ZA971023B (en) | 1996-02-09 | 1997-02-07 | Quinolonecarboxylic acid derivatives or their salts. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6025370A (hu) |
| EP (1) | EP0882725B1 (hu) |
| KR (1) | KR100276477B1 (hu) |
| CN (2) | CN1100053C (hu) |
| AT (1) | ATE229950T1 (hu) |
| AU (1) | AU711914B2 (hu) |
| CA (1) | CA2242242C (hu) |
| DE (1) | DE69717970T2 (hu) |
| DK (1) | DK0882725T3 (hu) |
| ES (1) | ES2188890T3 (hu) |
| HK (1) | HK1039118B (hu) |
| HU (1) | HU228567B1 (hu) |
| IL (1) | IL124944A (hu) |
| NO (1) | NO316666B1 (hu) |
| NZ (1) | NZ330775A (hu) |
| PT (1) | PT882725E (hu) |
| WO (1) | WO1997029102A1 (hu) |
| ZA (1) | ZA971023B (hu) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999014214A1 (en) | 1997-09-15 | 1999-03-25 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
| US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
| TW593308B (en) | 1997-10-27 | 2004-06-21 | Toyama Chemical Co Ltd | Processes for producing 7-isoindoline-quinolonecarboxylic acid derivative and its intermediate |
| DK1070713T3 (da) * | 1998-04-06 | 2006-12-27 | Toyama Chemical Co Ltd | Quinoloncarboxylsyrederivater eller salte deraf |
| JP4499846B2 (ja) * | 1998-05-07 | 2010-07-07 | 富山化学工業株式会社 | ７−イソインドリン−キノロンカルボン酸誘導体の製造法並びにイソインドリン−５−ボロン酸誘導体の製造法 |
| JP4549461B2 (ja) * | 1998-08-31 | 2010-09-22 | 富山化学工業株式会社 | ７−ブロモ−キノロンカルボン酸誘導体の製造法 |
| JP2000229946A (ja) * | 1998-12-10 | 2000-08-22 | Toyama Chem Co Ltd | キノロンカルボン酸の製造法およびその中間体 |
| CA2367373C (en) | 1999-03-17 | 2011-09-20 | Daiichi Pharmaceutical Co., Ltd. | Medicinal compositions |
| PL212421B1 (pl) * | 2002-03-12 | 2012-09-28 | Bristol Myers Squibb Co | Kompozycja farmaceutyczna w postaci zawiesiny kwasowego leku i sposób jej wytwarzania oraz sposób maskowania gorzkiego lub innego nieprzyjemnego smaku leku |
| WO2004113321A1 (ja) * | 2003-06-19 | 2004-12-29 | Daiichi Pharmaceutical Co., Ltd. | 選択的なアミノ置換基導入法 |
| KR100981351B1 (ko) * | 2003-10-29 | 2010-09-10 | 주식회사 엘지생명과학 | 7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법 |
| US20090156577A1 (en) * | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| EP1873134B1 (en) * | 2005-03-03 | 2013-02-13 | JNC Corporation | Chlorofluorobenzene liquid crystalline compound, liquid crystal composition, and liquid crystal display element |
| CA2647457C (en) | 2006-03-28 | 2011-05-24 | The Procter & Gamble Company | A hydride reduction process for preparing quinolone intermediates |
| MX2008012488A (es) | 2006-03-28 | 2008-10-10 | Procter & Gamble | Un proceso de acoplamiento para preparar intermedios de quinolona. |
| US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
| CN101298418B (zh) * | 2008-06-13 | 2010-12-15 | 江苏康鹏农化有限公司 | 3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法 |
| CN102212056A (zh) * | 2010-04-09 | 2011-10-12 | 山东轩竹医药科技有限公司 | 新的双环喹诺酮类化合物 |
| WO2013121439A2 (en) * | 2012-02-15 | 2013-08-22 | Glenmark Generics Limited | Process for garenoxacin mesylate |
| GB201516614D0 (en) * | 2015-09-18 | 2015-11-04 | Redx Pharma Plc | Antibacterial compounds |
| CN105837555B (zh) * | 2016-03-31 | 2019-01-25 | 南京华威医药科技集团有限公司 | 加雷沙星及其中间体制备方法 |
| CN111620901B (zh) * | 2020-06-08 | 2023-03-21 | 蚌埠医学院第二附属医院 | 一种含硅氧烷基的氟喹诺酮化合物、其制备方法及用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6199835A (ja) * | 1984-10-22 | 1986-05-17 | Shimadzu Corp | 振動試験機の波形補正装置 |
| MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
| PL166381B1 (pl) * | 1989-08-16 | 1995-05-31 | Pfizer | Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL |
| EG20543A (en) * | 1992-10-30 | 1999-07-31 | Procter & Gamble | Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones |
| JPH07300472A (ja) * | 1992-12-28 | 1995-11-14 | Korea Res Inst Chem Technol | 新規キノロンカルボン酸誘導体およびその製造方法 |
| JPH06199835A (ja) * | 1993-01-08 | 1994-07-19 | Hokuriku Seiyaku Co Ltd | ８−ジフルオロメトキシキノリン−３−カルボン酸誘導体 |
| DE4301246A1 (de) * | 1993-01-19 | 1994-07-21 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäurederivate |
| JPH0848629A (ja) * | 1994-08-08 | 1996-02-20 | Dainippon Pharmaceut Co Ltd | ピリドンカルボン酸誘導体およびそれを有効成分とする抗ピロリ菌剤 |
| NZ290946A (en) * | 1994-08-12 | 1997-12-19 | Toyama Chemical Co Ltd | Quinolone- or naphthyridone-carboxylic acid derivatives |
-
1997
- 1997-02-07 DK DK97902618T patent/DK0882725T3/da active
- 1997-02-07 CN CN97192130A patent/CN1100053C/zh not_active Expired - Lifetime
- 1997-02-07 WO PCT/JP1997/000317 patent/WO1997029102A1/ja active IP Right Grant
- 1997-02-07 CA CA002242242A patent/CA2242242C/en not_active Expired - Lifetime
- 1997-02-07 PT PT97902618T patent/PT882725E/pt unknown
- 1997-02-07 ZA ZA9701023A patent/ZA971023B/xx unknown
- 1997-02-07 ES ES97902618T patent/ES2188890T3/es not_active Expired - Lifetime
- 1997-02-07 NZ NZ330775A patent/NZ330775A/xx not_active IP Right Cessation
- 1997-02-07 DE DE69717970T patent/DE69717970T2/de not_active Expired - Lifetime
- 1997-02-07 CN CNB011012323A patent/CN100395244C/zh not_active Expired - Lifetime
- 1997-02-07 AU AU16701/97A patent/AU711914B2/en not_active Expired
- 1997-02-07 KR KR1019980706138A patent/KR100276477B1/ko not_active IP Right Cessation
- 1997-02-07 IL IL12494497A patent/IL124944A/xx not_active IP Right Cessation
- 1997-02-07 US US09/125,016 patent/US6025370A/en not_active Expired - Lifetime
- 1997-02-07 EP EP97902618A patent/EP0882725B1/en not_active Expired - Lifetime
- 1997-02-07 AT AT97902618T patent/ATE229950T1/de active
- 1997-02-07 HU HU9901966A patent/HU228567B1/hu unknown
-
1998
- 1998-08-07 NO NO19983625A patent/NO316666B1/no not_active IP Right Cessation
-
2002
- 2002-01-16 HK HK02100336.1A patent/HK1039118B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2242242C (en) | 2001-08-07 |
| WO1997029102A1 (fr) | 1997-08-14 |
| CN1314355A (zh) | 2001-09-26 |
| AU711914B2 (en) | 1999-10-21 |
| NO316666B1 (no) | 2004-03-29 |
| IL124944A0 (en) | 1999-01-26 |
| NZ330775A (en) | 1999-08-30 |
| PT882725E (pt) | 2003-04-30 |
| DE69717970D1 (de) | 2003-01-30 |
| HK1039118A1 (en) | 2002-04-12 |
| EP0882725A1 (en) | 1998-12-09 |
| HUP9901966A3 (en) | 2002-01-28 |
| NO983625L (no) | 1998-08-07 |
| CN1100053C (zh) | 2003-01-29 |
| EP0882725A4 (en) | 1999-05-06 |
| DE69717970T2 (de) | 2003-04-30 |
| ATE229950T1 (de) | 2003-01-15 |
| KR19990082406A (ko) | 1999-11-25 |
| CN1210533A (zh) | 1999-03-10 |
| HK1039118B (zh) | 2009-01-30 |
| AU1670197A (en) | 1997-08-28 |
| HU228567B1 (en) | 2013-04-29 |
| US6025370A (en) | 2000-02-15 |
| NO983625D0 (no) | 1998-08-07 |
| KR100276477B1 (ko) | 2000-12-15 |
| IL124944A (en) | 2003-06-24 |
| CA2242242A1 (en) | 1997-08-14 |
| HUP9901966A2 (hu) | 1999-09-28 |
| EP0882725B1 (en) | 2002-12-18 |
| CN100395244C (zh) | 2008-06-18 |
| DK0882725T3 (da) | 2003-01-13 |
| ES2188890T3 (es) | 2003-07-01 |
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