ZA962755B - 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives. - Google Patents

1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives.

Info

Publication number
ZA962755B
ZA962755B ZA9602755A ZA962755A ZA962755B ZA 962755 B ZA962755 B ZA 962755B ZA 9602755 A ZA9602755 A ZA 9602755A ZA 962755 A ZA962755 A ZA 962755A ZA 962755 B ZA962755 B ZA 962755B
Authority
ZA
South Africa
Prior art keywords
phenylalkenyl
imidazol
dihydro
derivatives
Prior art date
Application number
ZA9602755A
Other languages
English (en)
Inventor
Eddy Jean Edgar Freyne
Gaston Stanislas Marcell Diels
Jose Ignacio Andres-Gil
Francisco Javi Fernandez-Gadea
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA962755B publication Critical patent/ZA962755B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9602755A 1995-04-06 1996-04-04 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives. ZA962755B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95200869 1995-04-06

Publications (1)

Publication Number Publication Date
ZA962755B true ZA962755B (en) 1997-10-06

Family

ID=8220174

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9602755A ZA962755B (en) 1995-04-06 1996-04-04 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives.

Country Status (16)

Country Link
US (1) US5952510A (de)
EP (1) EP0819123B1 (de)
JP (1) JP3963475B2 (de)
KR (1) KR100400161B1 (de)
CN (1) CN1068590C (de)
AR (1) AR003412A1 (de)
AT (1) ATE380794T1 (de)
AU (1) AU703235B2 (de)
CA (1) CA2216546C (de)
DE (1) DE69637363T2 (de)
ES (1) ES2297837T3 (de)
IL (1) IL117808A (de)
MY (1) MY113446A (de)
TW (1) TW424087B (de)
WO (1) WO1996031486A1 (de)
ZA (1) ZA962755B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU719561B2 (en) * 1996-10-02 2000-05-11 Janssen Pharmaceutica N.V. PDE IV inhibiting 2-cyanoiminoimidazole derivatives
AU760771B2 (en) * 1998-04-01 2003-05-22 Janssen Pharmaceutica N.V. PDE IV inhibiting pyridine derivatives
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
GB0321754D0 (en) * 2003-09-17 2003-10-15 Smiths Group Plc Apparatus
US8354434B2 (en) * 2006-01-30 2013-01-15 Purdue Pharma L.P. Cyclourea compounds as calcium channel blockers
CA2792844C (en) 2010-03-12 2014-12-09 Omeros Corporation Pde10 inhibitors and related compositions and methods
NZ716462A (en) 2014-04-28 2017-11-24 Omeros Corp Optically active pde10 inhibitor
NZ630810A (en) 2014-04-28 2016-03-31 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
AU2016250843A1 (en) 2015-04-24 2017-10-12 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2017079678A1 (en) 2015-11-04 2017-05-11 Omeros Corporation Solid state forms of a pde10 inhibitor
PT3411361T (pt) 2016-02-03 2021-01-29 Rigel Pharmaceuticals Inc Compostos ativadores de nrf2 e suas utilizações
CN108699034B (zh) * 2016-02-03 2020-12-11 参宿七制药股份有限公司 Nrf2活化性化合物及其用途
DE102017127776A1 (de) 2017-11-24 2019-05-29 Henkel Ag & Co. Kgaa Hydrolyselabile Heterocyclen von Riechstoffketonen oder -aldehyden

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551417A (en) * 1967-08-28 1970-12-29 Universal Oil Prod Co Pesticidal heterocyclic sulfides
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
CA2095429A1 (en) * 1990-11-06 1992-05-07 Paul E. Bender Imidazolidinone compounds
NZ257955A (en) * 1992-12-02 1996-05-28 Pfizer Catechol diethers pharmaceutical compositions
GB9226830D0 (en) * 1992-12-23 1993-02-17 Celltech Ltd Chemical compounds
GB9304919D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
US5677464A (en) * 1994-05-31 1997-10-14 Takeda Chemical Industries, Ltd. Production of optically active triazole compounds and their intermediates

Also Published As

Publication number Publication date
KR19980703450A (ko) 1998-11-05
AU703235B2 (en) 1999-03-18
CN1068590C (zh) 2001-07-18
CA2216546A1 (en) 1996-10-10
CA2216546C (en) 2009-01-06
MY113446A (en) 2002-02-28
EP0819123A1 (de) 1998-01-21
TW424087B (en) 2001-03-01
EP0819123B1 (de) 2007-12-12
ES2297837T3 (es) 2008-05-01
JP3963475B2 (ja) 2007-08-22
ATE380794T1 (de) 2007-12-15
AU5275696A (en) 1996-10-23
AR003412A1 (es) 1998-08-05
IL117808A (en) 2001-01-11
WO1996031486A1 (en) 1996-10-10
DE69637363D1 (de) 2008-01-24
KR100400161B1 (ko) 2004-02-05
DE69637363T2 (de) 2008-12-04
IL117808A0 (en) 1996-08-04
CN1181071A (zh) 1998-05-06
JPH11503137A (ja) 1999-03-23
US5952510A (en) 1999-09-14

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