ZA961948B - 6-aryl pyrazoloÚ3,4-d¾pyrimidin-4-ones and compositions and methods of use thereof - Google Patents
6-aryl pyrazoloÚ3,4-d¾pyrimidin-4-ones and compositions and methods of use thereofInfo
- Publication number
- ZA961948B ZA961948B ZA961948A ZA961948A ZA961948B ZA 961948 B ZA961948 B ZA 961948B ZA 961948 A ZA961948 A ZA 961948A ZA 961948 A ZA961948 A ZA 961948A ZA 961948 B ZA961948 B ZA 961948B
- Authority
- ZA
- South Africa
- Prior art keywords
- aryl
- ones
- compositions
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40226195A | 1995-03-10 | 1995-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA961948B true ZA961948B (en) | 1996-09-17 |
Family
ID=23591191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA961948A ZA961948B (en) | 1995-03-10 | 1996-03-11 | 6-aryl pyrazoloÚ3,4-d¾pyrimidin-4-ones and compositions and methods of use thereof |
Country Status (13)
Country | Link |
---|---|
US (2) | US5736548A (xx) |
EP (1) | EP0813534A4 (xx) |
JP (1) | JPH11501926A (xx) |
KR (1) | KR19980702892A (xx) |
AU (1) | AU708809B2 (xx) |
CA (1) | CA2211729A1 (xx) |
CZ (1) | CZ280697A3 (xx) |
HU (1) | HUP9801394A3 (xx) |
NO (1) | NO974150L (xx) |
NZ (1) | NZ303886A (xx) |
PL (1) | PL322452A1 (xx) |
WO (1) | WO1996028448A1 (xx) |
ZA (1) | ZA961948B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6664261B2 (en) | 1996-02-07 | 2003-12-16 | Neurocrine Biosciences, Inc. | Pyrazolopyrimidines as CRF receptor antagonists |
DE19709877A1 (de) | 1997-03-11 | 1998-09-17 | Bayer Ag | 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate |
NZ338075A (en) | 1997-04-25 | 2000-10-27 | Pfizer Ltd | Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PED5) for the treatment of sexual dysfunction |
GB9722520D0 (en) | 1997-10-24 | 1997-12-24 | Pfizer Ltd | Compounds |
TR200003039T2 (tr) * | 1998-04-20 | 2001-01-22 | Pfizer Inc. | Seksüel fonksiyon bozukluklarının tedavisi için pirazolopirimidinon cGMP PDE5 inhibitörleri |
GB9823101D0 (en) | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
GB9823102D0 (en) | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
GB9823103D0 (en) | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
US6225315B1 (en) * | 1998-11-30 | 2001-05-01 | Pfizer Inc | Method of treating nitrate-induced tolerance |
GB9828340D0 (en) * | 1998-12-22 | 1999-02-17 | Novartis Ag | Organic compounds |
TWI265925B (en) | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
DZ3218A1 (fr) | 1999-10-11 | 2001-04-19 | Pfizer | Pyrimidine-7-ones 5-(2-substitutees-5-heterocyclylsulphonylpyride-3-yl)-dihydropyrazolo[4,3-d] servant d'inhibiteurs de la phosphodiesterase |
IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
GEP20084329B (en) | 2003-04-29 | 2008-03-25 | Pfizer Ltd | 5,7-diaminopyrazolo [4,3-d] pyrimidines useful in the treatment of hypertension |
AU2004274403A1 (en) * | 2003-09-03 | 2005-03-31 | Aventis Pharmaceuticals Inc. | 5-aryl-Pyrazolo(4,3-d)pyrimidines, pyridines, and pyrazines and related compounds |
KR20140103925A (ko) | 2011-12-09 | 2014-08-27 | 키에시 파르마슈티시 엣스. 피. 에이. | 4-히드록시-1,2,3,4-테트라히드로나프탈렌-1-일 우레아 및 호흡기 질환의 치료에서의 이들의 용도 |
BR112014030410A2 (pt) * | 2012-06-07 | 2017-06-27 | Hoffmann La Roche | inibidores de pirazolopirimidona e pirazolopiridona de tanquirase |
US8883857B2 (en) | 2012-12-07 | 2014-11-11 | Baylor College Of Medicine | Small molecule xanthine oxidase inhibitors and methods of use |
EP3562828A1 (en) | 2016-12-28 | 2019-11-06 | Dart NeuroScience LLC | Substituted pyrazolopyrimidinone compounds as pde2 inhibitors |
MX2020005447A (es) | 2017-11-27 | 2020-12-03 | Dart Neuroscience Llc | Compuestos de furanopirimidina sustituida como inhibidores de pde1. |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3211732A (en) * | 1965-10-12 | Pyrazolob:x-d]pyrlil/hdines | ||
US3165520A (en) * | 1965-01-12 | Certificate of correction | ||
GB937722A (en) * | 1960-05-11 | 1963-09-25 | Ciba Ltd | New pyrazolopyrimidines and process for the preparation thereof |
CH398626A (de) * | 1960-05-11 | 1966-03-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
GB1284084A (en) * | 1969-04-17 | 1972-08-02 | Delmar Chem | PROCESS FOR MAKING 1H-PYRAZOLO[3,4-d]PYRIMIDINES |
US3732225A (en) * | 1970-07-23 | 1973-05-08 | Squibb & Sons Inc | Pyrazolo(3,4-d)pyrimidine derivatives |
US4666908A (en) * | 1985-04-05 | 1987-05-19 | Warner-Lambert Company | 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use |
WO1988000192A1 (en) * | 1986-06-26 | 1988-01-14 | Warner-Lambert Company | 5-SUBSTITUTED PYRAZOLO[4,3-d]PYRIMIDIN-7-ONES |
US5075310A (en) * | 1988-07-01 | 1991-12-24 | Smith Kline & French Laboratories, Ltd. | Pyrimidone derivatives as bronchodilators |
GB9013750D0 (en) * | 1990-06-20 | 1990-08-08 | Pfizer Ltd | Therapeutic agents |
GB9121028D0 (en) * | 1991-10-03 | 1991-11-13 | Pfizer Ltd | Therapeutic agents |
US5294612A (en) * | 1992-03-30 | 1994-03-15 | Sterling Winthrop Inc. | 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof |
GB9315017D0 (en) * | 1993-07-20 | 1993-09-01 | Glaxo Lab Sa | Chemical compounds |
-
1996
- 1996-03-05 WO PCT/US1996/003100 patent/WO1996028448A1/en not_active Application Discontinuation
- 1996-03-05 CZ CZ972806A patent/CZ280697A3/cs unknown
- 1996-03-05 PL PL96322452A patent/PL322452A1/xx unknown
- 1996-03-05 EP EP96907191A patent/EP0813534A4/en not_active Withdrawn
- 1996-03-05 CA CA002211729A patent/CA2211729A1/en not_active Abandoned
- 1996-03-05 JP JP8527712A patent/JPH11501926A/ja active Pending
- 1996-03-05 AU AU50933/96A patent/AU708809B2/en not_active Ceased
- 1996-03-05 NZ NZ303886A patent/NZ303886A/en unknown
- 1996-03-05 KR KR1019970706300A patent/KR19980702892A/ko not_active Application Discontinuation
- 1996-03-05 HU HU9801394A patent/HUP9801394A3/hu unknown
- 1996-03-11 ZA ZA961948A patent/ZA961948B/xx unknown
-
1997
- 1997-01-22 US US08/788,893 patent/US5736548A/en not_active Expired - Fee Related
- 1997-09-09 NO NO974150A patent/NO974150L/no unknown
-
1998
- 1998-01-30 US US09/016,572 patent/US5958929A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2211729A1 (en) | 1996-09-19 |
NO974150L (no) | 1997-11-07 |
NZ303886A (en) | 1998-11-25 |
HUP9801394A2 (hu) | 1998-10-28 |
EP0813534A4 (en) | 1998-06-10 |
AU708809B2 (en) | 1999-08-12 |
KR19980702892A (ko) | 1998-08-05 |
CZ280697A3 (cs) | 1998-04-15 |
US5736548A (en) | 1998-04-07 |
MX9706878A (es) | 1998-06-28 |
JPH11501926A (ja) | 1999-02-16 |
EP0813534A1 (en) | 1997-12-29 |
HUP9801394A3 (en) | 2000-07-28 |
WO1996028448A1 (en) | 1996-09-19 |
NO974150D0 (no) | 1997-09-09 |
PL322452A1 (en) | 1998-02-02 |
US5958929A (en) | 1999-09-28 |
AU5093396A (en) | 1996-10-02 |
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