ZA954738B - Tetracyclic piperidine and 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them - Google Patents

Tetracyclic piperidine and 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA954738B
ZA954738B ZA954738A ZA954738A ZA954738B ZA 954738 B ZA954738 B ZA 954738B ZA 954738 A ZA954738 A ZA 954738A ZA 954738 A ZA954738 A ZA 954738A ZA 954738 B ZA954738 B ZA 954738B
Authority
ZA
South Africa
Prior art keywords
tetracyclic
piperidine
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA954738A
Other languages
English (en)
Inventor
Jean-Louis Peglion
Joen Vian
Bertrand Goument
Mark Millan
Valerie Audinot
Jean-Charles Schwartz
Pierre Sokoloff
Original Assignee
Adir
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir, Inst Nat Sante Rech Med filed Critical Adir
Publication of ZA954738B publication Critical patent/ZA954738B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA954738A 1994-06-08 1995-06-08 Tetracyclic piperidine and 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them ZA954738B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9406985A FR2721027B1 (fr) 1994-06-08 1994-06-08 Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant.

Publications (1)

Publication Number Publication Date
ZA954738B true ZA954738B (en) 1996-01-26

Family

ID=9463983

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA954738A ZA954738B (en) 1994-06-08 1995-06-08 Tetracyclic piperidine and 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (2) US5593989A (fi)
EP (1) EP0686637B1 (fi)
JP (1) JP3157418B2 (fi)
CN (1) CN1050358C (fi)
AT (1) ATE192155T1 (fi)
AU (1) AU681780B2 (fi)
CA (1) CA2151096C (fi)
DE (1) DE69516457T2 (fi)
DK (1) DK0686637T3 (fi)
ES (1) ES2147825T3 (fi)
FI (1) FI111948B (fi)
FR (1) FR2721027B1 (fi)
GR (1) GR3033762T3 (fi)
NO (1) NO304741B1 (fi)
NZ (1) NZ272298A (fi)
PT (1) PT686637E (fi)
ZA (1) ZA954738B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2741074B1 (fr) * 1995-11-09 1997-12-19 Adir Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2291026A1 (en) * 1997-06-05 1998-12-10 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use
WO2004092154A1 (en) * 2003-04-03 2004-10-28 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
FR2906249B1 (fr) 2006-09-26 2008-12-19 Servier Lab Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1204745A (en) * 1981-11-20 1986-05-20 Merck Co. Hexahydronaphth (1,2-b) -1,4 -oxazines
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
US4435231A (en) * 1982-03-31 1984-03-06 The United States Of America As Represented By The United States Department Of Energy Cold worked ferritic alloys and components
ATE64735T1 (de) * 1984-05-10 1991-07-15 Ciba Geigy Ag Benzo-(pyrano und thiopyrano)-pyridine.
US4774243A (en) * 1985-12-24 1988-09-27 Merck & Co., Inc. Dopamine agonists for treating elevated intraocular pressure
US4792548A (en) * 1986-05-21 1988-12-20 Warner-Lambert Company Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use
US5294618A (en) * 1989-07-28 1994-03-15 Merck Sharp & Dohme Limited Octahydrobenzisoquinoline derivatives as antipsychotic agents
WO1993024471A1 (en) 1992-06-02 1993-12-09 Whitby Research, Inc. Substituted naphthoxazines useful as dopaminergics

Also Published As

Publication number Publication date
AU681780B2 (en) 1997-09-04
CN1050358C (zh) 2000-03-15
NO952249D0 (no) 1995-06-07
ATE192155T1 (de) 2000-05-15
DE69516457D1 (de) 2000-05-31
NO304741B1 (no) 1999-02-08
FR2721027A1 (fr) 1995-12-15
EP0686637A1 (fr) 1995-12-13
JPH07330778A (ja) 1995-12-19
NO952249L (no) 1995-12-11
AU2052395A (en) 1995-12-14
JP3157418B2 (ja) 2001-04-16
NZ272298A (en) 1996-05-28
EP0686637B1 (fr) 2000-04-26
PT686637E (pt) 2000-08-31
DE69516457T2 (de) 2001-01-18
GR3033762T3 (en) 2000-10-31
US5668142A (en) 1997-09-16
US5593989A (en) 1997-01-14
FI111948B (fi) 2003-10-15
ES2147825T3 (es) 2000-10-01
FI952802A (fi) 1995-12-09
CA2151096C (fr) 2003-07-08
CN1120541A (zh) 1996-04-17
FI952802A0 (fi) 1995-06-07
DK0686637T3 (da) 2000-09-18
FR2721027B1 (fr) 1996-07-19
CA2151096A1 (fr) 1995-12-09

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