ZA949303B - Novel benzenesulfonylimine derivates as inhibitors of IL-1 action. - Google Patents
Novel benzenesulfonylimine derivates as inhibitors of IL-1 action.Info
- Publication number
- ZA949303B ZA949303B ZA949303A ZA949303A ZA949303B ZA 949303 B ZA949303 B ZA 949303B ZA 949303 A ZA949303 A ZA 949303A ZA 949303 A ZA949303 A ZA 949303A ZA 949303 B ZA949303 B ZA 949303B
- Authority
- ZA
- South Africa
- Prior art keywords
- inhibitors
- pct
- action
- derivates
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15901493A | 1993-11-29 | 1993-11-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA949303B true ZA949303B (en) | 1995-08-07 |
Family
ID=22570705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA949303A ZA949303B (en) | 1993-11-29 | 1994-11-23 | Novel benzenesulfonylimine derivates as inhibitors of IL-1 action. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5684017A (hu) |
EP (1) | EP0731791B1 (hu) |
JP (1) | JPH09506345A (hu) |
KR (1) | KR100340375B1 (hu) |
CN (1) | CN1044116C (hu) |
AT (1) | ATE177083T1 (hu) |
AU (1) | AU683114B2 (hu) |
CA (1) | CA2175458C (hu) |
DE (1) | DE69416859T2 (hu) |
DK (1) | DK0731791T3 (hu) |
ES (1) | ES2131297T3 (hu) |
FI (1) | FI109901B (hu) |
GR (1) | GR3029827T3 (hu) |
HU (1) | HU219565B (hu) |
IL (1) | IL111776A (hu) |
NO (1) | NO306211B1 (hu) |
NZ (1) | NZ276577A (hu) |
PT (1) | PT731791E (hu) |
TW (1) | TW279161B (hu) |
WO (1) | WO1995014669A1 (hu) |
ZA (1) | ZA949303B (hu) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US6562629B1 (en) | 1999-08-11 | 2003-05-13 | Cedars-Sinai Medical Center | Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
DE19705133A1 (de) * | 1997-02-11 | 1998-08-13 | Hoechst Ag | Sulfonamid-substituierte Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
AU9696198A (en) * | 1997-10-17 | 1999-05-10 | Aventis Pharmaceuticals Products Inc. | Therapeutic uses of quinoline derivatives |
DE19858253A1 (de) * | 1998-12-17 | 2000-06-21 | Aventis Pharma Gmbh | Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
JP4212470B2 (ja) | 2001-06-26 | 2009-01-21 | アムジェン フレモント インク. | Opglへの抗体 |
CA2451699A1 (en) * | 2001-06-26 | 2003-01-09 | Beth Israel Deaconess Medical Center | Compositions and methods for inhibiting platelet activation and thrombosis |
CA2511823A1 (en) | 2002-12-30 | 2004-07-22 | Amgen Inc. | Combination therapy with co-stimulatory factors |
KR100687522B1 (ko) * | 2005-05-28 | 2007-02-27 | 한국화학연구원 | 2,2-디메틸-3-에스테르-4-알콕시-6-알킬 아미노벤조피란 유도체를 유효성분으로 함유하는 pge2 활성에 관련된 염증질환 치료제 |
CN104447489B (zh) * | 2014-12-29 | 2017-01-11 | 南京工业大学 | 3,4-二芳基马来酰亚胺衍生物及其制备方法与应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US3742951A (en) * | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
US3996934A (en) * | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
US3921636A (en) * | 1973-01-15 | 1975-11-25 | Alza Corp | Novel drug delivery device |
US4031894A (en) * | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
GB8719102D0 (en) * | 1987-08-12 | 1987-09-16 | Merck Sharp & Dohme | Therapeutic agents |
AU660969B2 (en) * | 1991-02-27 | 1995-07-13 | Merrell Pharmaceuticals Inc. | NMDA antagonists |
AU682736B2 (en) * | 1993-11-29 | 1997-10-16 | Merrell Pharmaceuticals Inc. | Heterocyclic benzenesulfonylimine derivatives as inhibitors of IL-1 action |
-
1994
- 1994-11-03 CN CN94194304A patent/CN1044116C/zh not_active Expired - Fee Related
- 1994-11-03 JP JP7515081A patent/JPH09506345A/ja active Pending
- 1994-11-03 KR KR1019960702804A patent/KR100340375B1/ko not_active IP Right Cessation
- 1994-11-03 DE DE69416859T patent/DE69416859T2/de not_active Expired - Fee Related
- 1994-11-03 AU AU10879/95A patent/AU683114B2/en not_active Ceased
- 1994-11-03 ES ES95901762T patent/ES2131297T3/es not_active Expired - Lifetime
- 1994-11-03 US US08/649,663 patent/US5684017A/en not_active Expired - Fee Related
- 1994-11-03 HU HU9601435A patent/HU219565B/hu not_active IP Right Cessation
- 1994-11-03 CA CA002175458A patent/CA2175458C/en not_active Expired - Fee Related
- 1994-11-03 EP EP95901762A patent/EP0731791B1/en not_active Expired - Lifetime
- 1994-11-03 WO PCT/US1994/012658 patent/WO1995014669A1/en active IP Right Grant
- 1994-11-03 PT PT95901762T patent/PT731791E/pt unknown
- 1994-11-03 AT AT95901762T patent/ATE177083T1/de not_active IP Right Cessation
- 1994-11-03 DK DK95901762T patent/DK0731791T3/da active
- 1994-11-03 NZ NZ276577A patent/NZ276577A/en unknown
- 1994-11-23 ZA ZA949303A patent/ZA949303B/xx unknown
- 1994-11-24 TW TW083111032A patent/TW279161B/zh active
- 1994-11-27 IL IL11177694A patent/IL111776A/xx active IP Right Grant
-
1996
- 1996-05-28 NO NO962155A patent/NO306211B1/no unknown
- 1996-05-28 FI FI962235A patent/FI109901B/fi not_active IP Right Cessation
-
1999
- 1999-03-30 GR GR990400918T patent/GR3029827T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU1087995A (en) | 1995-06-13 |
FI962235A0 (fi) | 1996-05-28 |
FI962235A (fi) | 1996-05-28 |
DE69416859T2 (de) | 1999-08-05 |
EP0731791B1 (en) | 1999-03-03 |
HU219565B (hu) | 2001-05-28 |
TW279161B (hu) | 1996-06-21 |
DE69416859D1 (de) | 1999-04-08 |
CN1136311A (zh) | 1996-11-20 |
IL111776A (en) | 1999-06-20 |
GR3029827T3 (en) | 1999-06-30 |
PT731791E (pt) | 2000-11-30 |
DK0731791T3 (da) | 1999-09-27 |
AU683114B2 (en) | 1997-10-30 |
CA2175458C (en) | 1999-03-02 |
IL111776A0 (en) | 1995-01-24 |
JPH09506345A (ja) | 1997-06-24 |
EP0731791A1 (en) | 1996-09-18 |
CN1044116C (zh) | 1999-07-14 |
NO962155D0 (no) | 1996-05-28 |
US5684017A (en) | 1997-11-04 |
ES2131297T3 (es) | 1999-07-16 |
KR960706476A (ko) | 1996-12-09 |
HU9601435D0 (en) | 1996-07-29 |
FI109901B (fi) | 2002-10-31 |
CA2175458A1 (en) | 1995-06-01 |
NO306211B1 (no) | 1999-10-04 |
NZ276577A (en) | 1997-11-24 |
WO1995014669A1 (en) | 1995-06-01 |
KR100340375B1 (ko) | 2002-11-13 |
HUT76273A (en) | 1997-07-28 |
NO962155L (no) | 1996-05-28 |
ATE177083T1 (de) | 1999-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR27835A (tr) | Sübstitüe edilmis azadiokzasikloalkenler. | |
ZA949303B (en) | Novel benzenesulfonylimine derivates as inhibitors of IL-1 action. | |
GR3032506T3 (en) | 3-aryl-2-isoxazolines as antiinflammatory agents | |
CA2165824A1 (fr) | Utilisation du modafinil pour la fabrication d'un medicament ayant un effet sur les apnees du sommeil et les troubles ventilatoires d'origine centrale | |
CA2474511A1 (en) | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders | |
TW281671B (hu) | ||
HUT75315A (en) | N-substituted azabicycloheptane derivatives and use of them, for example, as neuroleptics | |
MX9703658A (es) | Barra de limpieza con altos niveles de emolientes y silice particulada. | |
AP9701142A0 (en) | 4,4-(Disubstituted) cyclohexan-1-ols monomers and related compounds. | |
AU6473296A (en) | Filling agent | |
ZA932748B (en) | Water-soluble retinoids | |
HUT76271A (en) | Substituted aminoalkylaminopyridines, process for producing them and their use | |
PL322847A1 (en) | Condensed b-carbolins |