ZA945655B - 1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivatives - Google Patents
1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivativesInfo
- Publication number
- ZA945655B ZA945655B ZA945655A ZA945655A ZA945655B ZA 945655 B ZA945655 B ZA 945655B ZA 945655 A ZA945655 A ZA 945655A ZA 945655 A ZA945655 A ZA 945655A ZA 945655 B ZA945655 B ZA 945655B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzimidazol
- benzenesulfonyl
- dihydro
- derivatives
- Prior art date
Links
- BPTIOJPNCPTPDO-UHFFFAOYSA-N 3-(benzenesulfonyl)-1h-benzimidazol-2-one Chemical class O=C1NC2=CC=CC=C2N1S(=O)(=O)C1=CC=CC=C1 BPTIOJPNCPTPDO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/22—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9309403A FR2708608B1 (fr) | 1993-07-30 | 1993-07-30 | Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA945655B true ZA945655B (en) | 1995-03-14 |
Family
ID=9449793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA945655A ZA945655B (en) | 1993-07-30 | 1994-07-29 | 1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivatives |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5585394A (xx) |
| EP (1) | EP0636614A1 (xx) |
| JP (1) | JPH07215947A (xx) |
| KR (1) | KR950003275A (xx) |
| CN (1) | CN1106804A (xx) |
| AU (1) | AU679535B2 (xx) |
| CA (1) | CA2129214A1 (xx) |
| FI (1) | FI943571A (xx) |
| FR (1) | FR2708608B1 (xx) |
| HU (1) | HUT67801A (xx) |
| IL (1) | IL110481A0 (xx) |
| NO (1) | NO304374B1 (xx) |
| NZ (1) | NZ264119A (xx) |
| RU (1) | RU2135477C1 (xx) |
| TW (1) | TW368500B (xx) |
| ZA (1) | ZA945655B (xx) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728712A (en) * | 1995-05-19 | 1998-03-17 | Chiroscience Limited | 3,4-disubstituted-phenylsulphonamides and their therapeutic use |
| US5756497A (en) * | 1996-03-01 | 1998-05-26 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| AU2388697A (en) * | 1996-04-19 | 1997-11-12 | Neurosearch A/S | 1-(4-piperidyl)-benzimidazoles having neurotrophic activity |
| DE19929076A1 (de) * | 1999-06-25 | 2000-12-28 | Aventis Pharma Gmbh | Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| JP4710140B2 (ja) * | 2000-01-20 | 2011-06-29 | 東レ・ファインケミカル株式会社 | ピロリン誘導体の製造法 |
| EP1280523A2 (en) * | 2000-05-03 | 2003-02-05 | Sucampo AG | Use of benzamide derivatives for the treatment of high ocular tension and glaucoma |
| US6653478B2 (en) | 2000-10-27 | 2003-11-25 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide Y modulators |
| EP1598339B1 (en) * | 2001-04-18 | 2009-06-24 | Euro-Celtique S.A. | 1-(4-amino-cyclohexyl)-1,3-dihydro-2h-benzimidazole-2-one derivatives and related compounds as nociceptin analogs and orl1 ligands for the treatment of pain |
| WO2005010003A1 (en) * | 2003-07-23 | 2005-02-03 | Wyeth | Sulfonyldihydroimid- azopyridinone compounds as 5-hydroxytryptamine-6 ligands |
| EP1654258A1 (en) * | 2003-07-23 | 2006-05-10 | Wyeth | Sulfonyldihydro- benzimidazolone compounds as 5-hydroxytryptamine-6 ligands |
| DE602005025755D1 (de) | 2004-06-04 | 2011-02-17 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
| US8138342B2 (en) * | 2004-10-12 | 2012-03-20 | High Point Pharmacueticals, LLC | 11β-hydroxysteroid dehydrogenase type 1 active spiro compounds |
| CA2627306A1 (en) * | 2005-11-01 | 2007-05-10 | Transtech Pharma, Inc. | Pharmaceutical use of substituted amides |
| WO2007051811A2 (en) * | 2005-11-01 | 2007-05-10 | Transtech Pharma | Pharmaceutical use of substituted amides |
| EP2007722A1 (en) * | 2006-03-21 | 2008-12-31 | High Point Pharmaceuticals, LLC | Adamantane derivatives for the treatment of the metabolic syndrome |
| CA2648074A1 (en) | 2006-04-07 | 2007-10-18 | High Point Pharmaceuticals, Llc | 11.beta.-hydroxysteroid dehydrogenase type 1 active compounds |
| DE102006024024A1 (de) * | 2006-05-23 | 2007-11-29 | Bayer Healthcare Aktiengesellschaft | Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung |
| WO2007144394A2 (en) * | 2006-06-16 | 2007-12-21 | High Point Pharmaceuticals, Llc. | Pharmaceutical use of substituted piperidine carboxamides |
| EP1878721A1 (en) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors |
| WO2008006702A1 (en) * | 2006-07-13 | 2008-01-17 | High Point Pharmaceuticals, Llc. | 11beta-hydroxysteroid dehydrogenase type 1 active compounds |
| MX2009002125A (es) * | 2006-08-26 | 2009-03-09 | Abbott Gmbh & Co Kg | Derivados de benzimidazolona sustituidos, medicamentos que los comprenden y su uso. |
| AU2008219326B2 (en) * | 2007-02-23 | 2012-12-13 | Vtv Therapeutics Llc | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
| US20110003856A1 (en) * | 2007-02-23 | 2011-01-06 | Soren Ebdrup | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
| US20110003852A1 (en) * | 2007-02-23 | 2011-01-06 | Soren Ebdrup | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
| US8334305B2 (en) | 2007-02-23 | 2012-12-18 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase |
| US8153798B2 (en) * | 2007-03-09 | 2012-04-10 | High Point Pharmaceuticals, Llc | Indole- and benzimidazole amides as hydroxysteroid dehydrogenase inhibitors |
| WO2008127924A1 (en) * | 2007-04-11 | 2008-10-23 | High Point Pharmaceuticals, Llc. | Novel compounds |
| WO2008134221A1 (en) * | 2007-04-24 | 2008-11-06 | High Point Pharmaceuticals, Llc | Pharmaceutical use of substituted amides |
| US8927549B2 (en) * | 2008-11-21 | 2015-01-06 | High Point Pharmaceuticals, Llc | Adamantyl benzamide derivatives |
| DE102008060967A1 (de) | 2008-12-06 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Phenylsulfonyltriazolone und ihre Verwendung |
| DE102010001064A1 (de) * | 2009-03-18 | 2010-09-23 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung |
| EA023221B1 (ru) | 2010-02-27 | 2016-05-31 | Байер Интеллектуэль Проперти Гмбх | СВЯЗАННЫЕ БИС-АРИЛЬНЫЕ АРИЛ-ТРИАЗОЛОНЫ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ, ИХ ПРИМЕНЕНИЕ, ЛЕКАРСТВЕННОЕ СРЕДСТВО НА ИХ ОСНОВЕ И ДВОЙНОЙ АНТАГОНИСТ V1a/V2-РЕЦЕПТОРОВ |
| DE102010040187A1 (de) | 2010-09-02 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Substituierte N-Phenethyl-triazolonacetamide und ihre Verwendung |
| DE102010040924A1 (de) | 2010-09-16 | 2012-03-22 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Phenylacet- und Phenylpropanamide und ihre Verwendung |
| AU2015342017B2 (en) | 2014-11-03 | 2020-02-06 | Bayer Pharma Aktiengesellschaft | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof |
| US9988367B2 (en) | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
| WO2024050312A2 (en) * | 2022-08-29 | 2024-03-07 | The Broad Institute, Inc. | T-type voltage-gated calcium channel potentiators |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3405136A (en) * | 1964-09-15 | 1968-10-08 | Upjohn Co | 1-phenylsulfonyl-2-benzimidazo-linones and 1-phenylsulfonyl-2-benzimidazolinethiones |
| BE792402A (fr) * | 1971-12-07 | 1973-06-07 | Ciba Geigy | Composes heterocycliques azotes et medicaments anthelminthiqueset antimicrobiens qui en contiennent |
| CH634307A5 (de) * | 1977-04-12 | 1983-01-31 | Ciba Geigy Ag | Anthelmintisch wirkende benzimidazolderivate, verfahren zu ihrer herstellung und mittel enthaltend diese wirkstoffe. |
| HU207051B (en) * | 1987-12-30 | 1993-03-01 | Chinoin Gyogyszer Es Vegyeszet | Process for producing 4-chloro-3-sulfamoylbenzoic acid hydrazides and pharmaceutical compositions comprising such compounds |
| US5338755A (en) * | 1990-07-31 | 1994-08-16 | Elf Sanofi | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present |
| FR2679903B1 (fr) * | 1991-08-02 | 1993-12-03 | Elf Sanofi | Derives de la n-sulfonyl indoline portant une fonction amidique, leur preparation, les compositions pharmaceutiques en contenant. |
| TW199153B (xx) * | 1990-08-07 | 1993-02-01 | Dtsuka Seiyaku Kk | |
| FR2686878B1 (fr) * | 1992-01-30 | 1995-06-30 | Sanofi Elf | Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant. |
-
1993
- 1993-07-30 FR FR9309403A patent/FR2708608B1/fr not_active Expired - Fee Related
-
1994
- 1994-07-28 EP EP94401736A patent/EP0636614A1/fr not_active Withdrawn
- 1994-07-28 IL IL11048194A patent/IL110481A0/xx unknown
- 1994-07-28 NZ NZ264119A patent/NZ264119A/en unknown
- 1994-07-29 NO NO942835A patent/NO304374B1/no not_active IP Right Cessation
- 1994-07-29 HU HU9402238A patent/HUT67801A/hu unknown
- 1994-07-29 FI FI943571A patent/FI943571A/fi unknown
- 1994-07-29 CA CA002129214A patent/CA2129214A1/en not_active Abandoned
- 1994-07-29 AU AU68788/94A patent/AU679535B2/en not_active Ceased
- 1994-07-29 RU RU94027577A patent/RU2135477C1/ru active
- 1994-07-29 TW TW083107082A patent/TW368500B/zh active
- 1994-07-29 ZA ZA945655A patent/ZA945655B/xx unknown
- 1994-07-29 US US08/282,547 patent/US5585394A/en not_active Expired - Fee Related
- 1994-07-30 CN CN94114901A patent/CN1106804A/zh active Pending
- 1994-07-30 KR KR1019940018913A patent/KR950003275A/ko not_active Application Discontinuation
- 1994-08-01 JP JP6199080A patent/JPH07215947A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU6878894A (en) | 1995-02-09 |
| CN1106804A (zh) | 1995-08-16 |
| FR2708608A1 (fr) | 1995-02-10 |
| HUT67801A (en) | 1995-05-29 |
| RU2135477C1 (ru) | 1999-08-27 |
| HU9402238D0 (en) | 1994-09-28 |
| FI943571A0 (fi) | 1994-07-29 |
| NO942835D0 (no) | 1994-07-29 |
| NZ264119A (en) | 1996-02-27 |
| FR2708608B1 (fr) | 1995-10-27 |
| US5585394A (en) | 1996-12-17 |
| JPH07215947A (ja) | 1995-08-15 |
| AU679535B2 (en) | 1997-07-03 |
| NO304374B1 (no) | 1998-12-07 |
| NO942835L (no) | 1995-01-31 |
| RU94027577A (ru) | 1996-05-27 |
| TW368500B (en) | 1999-09-01 |
| CA2129214A1 (en) | 1995-01-31 |
| KR950003275A (ko) | 1995-02-16 |
| EP0636614A1 (fr) | 1995-02-01 |
| IL110481A0 (en) | 1994-10-21 |
| FI943571A (fi) | 1995-01-31 |
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