ZA942882B - 2-Amino-4-quinolyl-dihydropyridines processes for their preparation and their use - Google Patents

2-Amino-4-quinolyl-dihydropyridines processes for their preparation and their use

Info

Publication number
ZA942882B
ZA942882B ZA942882A ZA942882A ZA942882B ZA 942882 B ZA942882 B ZA 942882B ZA 942882 A ZA942882 A ZA 942882A ZA 942882 A ZA942882 A ZA 942882A ZA 942882 B ZA942882 B ZA 942882B
Authority
ZA
South Africa
Prior art keywords
dihydropyridines
quinolyl
amino
processes
preparation
Prior art date
Application number
ZA942882A
Other languages
English (en)
Inventor
Juergen Stoltefuss
Siegfried Goldmann
Alexander Straub
Martin Bechem
Rainer Gross
Siegbert Hebisch
Joachim Huetter
Howard-Paul Rounding
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA942882B publication Critical patent/ZA942882B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA942882A 1993-04-27 1994-04-26 2-Amino-4-quinolyl-dihydropyridines processes for their preparation and their use ZA942882B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4313693A DE4313693A1 (de) 1993-04-27 1993-04-27 2-Amino-4-chinolin-dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
ZA942882B true ZA942882B (en) 1995-01-04

Family

ID=6486452

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA942882A ZA942882B (en) 1993-04-27 1994-04-26 2-Amino-4-quinolyl-dihydropyridines processes for their preparation and their use

Country Status (17)

Country Link
US (1) US5502062A (zh)
EP (1) EP0622369A3 (zh)
JP (1) JPH06329677A (zh)
CN (1) CN1100098A (zh)
AU (1) AU5922694A (zh)
CA (1) CA2121962A1 (zh)
CZ (1) CZ100094A3 (zh)
DE (1) DE4313693A1 (zh)
FI (1) FI941914A (zh)
HU (1) HUT70534A (zh)
IL (1) IL109437A0 (zh)
NO (1) NO941517L (zh)
NZ (1) NZ260382A (zh)
RU (1) RU94014256A (zh)
SK (1) SK47894A3 (zh)
TW (1) TW303365B (zh)
ZA (1) ZA942882B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ297278A (en) 1994-11-16 1999-06-29 Synaptic Pharma Corp 4-aryl dihydropyrimidine derivatives end medicaments
US6268369B1 (en) 1994-11-16 2001-07-31 Synaptic Pharmaceutical Corporation 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines
US6228861B1 (en) 1995-11-16 2001-05-08 Synaptic Pharmaceutical Corporation Dihydropyrimidines and uses thereof
US6172066B1 (en) 1996-05-16 2001-01-09 Synaptic Pharmaceutical Corporation Dihydropyrimidines and uses thereof
US6245773B1 (en) 1996-05-16 2001-06-12 Synaptic Pharmaceutical Corporation 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines
US6274585B1 (en) 1998-12-23 2001-08-14 Synaptic Pharmaceutical Corporation Dihydropyrimidines and uses thereof
US6680323B2 (en) 1998-12-23 2004-01-20 Synaptic Pharmaceutical Corporation Dihydropyrimidines and uses thereof
US6720324B2 (en) 2000-07-05 2004-04-13 Synaptic Pharmaceutical Corporation Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof
JP2007505137A (ja) * 2003-09-10 2007-03-08 シンタ ファーマシューティカルズ コーポレイション 代謝性障害を処置または予防するためのジヒドロピリジン化合物
CN100361656C (zh) * 2004-08-27 2008-01-16 石药集团中奇制药技术（石家庄）有限公司 丁苯酞自乳化释药体系及其制备方法和应用
US7080755B2 (en) * 2004-09-13 2006-07-25 Michael Handfield Smart tray for dispensing medicaments
US10119476B2 (en) 2011-09-16 2018-11-06 United Technologies Corporation Thrust bearing system with inverted non-contacting dynamic seals for gas turbine engine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2242786A1 (de) * 1972-08-31 1974-03-14 Bayer Ag Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
US3989708A (en) * 1972-08-31 1976-11-02 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3134945A1 (de) * 1981-09-03 1983-03-17 Bayer Ag, 5090 Leverkusen Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel
DE4011105A1 (de) * 1990-04-06 1991-10-10 Bayer Ag Neue 4-chinolyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5204472A (en) * 1990-04-06 1993-04-20 Bayer Aktiengesellschaft Quinoline and isoquinoline intermediates
DE4117750A1 (de) * 1991-05-30 1992-12-24 Bayer Ag Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4118707A1 (de) * 1991-06-07 1992-12-10 Bayer Ag Pharmazeutische verwendung von 3-formyl-1,4-dihydropyridinen, neue verbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
EP0622369A3 (de) 1996-02-28
FI941914A (fi) 1994-10-28
HUT70534A (en) 1995-10-30
RU94014256A (ru) 1997-02-20
DE4313693A1 (de) 1994-11-03
CA2121962A1 (en) 1994-10-28
EP0622369A2 (de) 1994-11-02
CZ100094A3 (en) 1994-11-16
NO941517L (no) 1994-10-28
AU5922694A (en) 1994-11-03
NZ260382A (en) 1996-01-26
HU9401208D0 (en) 1994-08-29
JPH06329677A (ja) 1994-11-29
FI941914A0 (fi) 1994-04-25
IL109437A0 (en) 1994-07-31
CN1100098A (zh) 1995-03-15
SK47894A3 (en) 1994-12-07
US5502062A (en) 1996-03-26
TW303365B (zh) 1997-04-21
NO941517D0 (zh) 1994-04-26

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