ZA935534B - Piperazine carboxamides - Google Patents

Piperazine carboxamides

Info

Publication number
ZA935534B
ZA935534B ZA935534A ZA935534A ZA935534B ZA 935534 B ZA935534 B ZA 935534B ZA 935534 A ZA935534 A ZA 935534A ZA 935534 A ZA935534 A ZA 935534A ZA 935534 B ZA935534 B ZA 935534B
Authority
ZA
South Africa
Prior art keywords
pct
nitrogen
methine
sec
different
Prior art date
Application number
ZA935534A
Other languages
English (en)
Inventor
Lisbeth Abramo
Curt Nordvi
Torbjorn Lundstedt
Knut Gunnar Olsson
Martin Brodszki
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of ZA935534B publication Critical patent/ZA935534B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA935534A 1992-07-31 1993-07-30 Piperazine carboxamides ZA935534B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9202266A SE9202266D0 (sv) 1992-07-31 1992-07-31 Novel piperazine carboxamides

Publications (1)

Publication Number Publication Date
ZA935534B true ZA935534B (en) 1994-02-24

Family

ID=20386860

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA935534A ZA935534B (en) 1992-07-31 1993-07-30 Piperazine carboxamides

Country Status (17)

Country Link
US (1) US5574031A (ja)
EP (1) EP0620814B1 (ja)
JP (1) JP3418195B2 (ja)
CN (1) CN1055687C (ja)
AT (1) ATE190973T1 (ja)
AU (1) AU666212B2 (ja)
CA (1) CA2141210A1 (ja)
DE (1) DE69328165T2 (ja)
DK (1) DK0620814T3 (ja)
ES (1) ES2144009T3 (ja)
GR (1) GR3033629T3 (ja)
IL (1) IL106502A (ja)
NZ (1) NZ254312A (ja)
PT (1) PT620814E (ja)
SE (1) SE9202266D0 (ja)
WO (1) WO1994003436A1 (ja)
ZA (1) ZA935534B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4533534B2 (ja) 1998-06-19 2010-09-01 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド グリコーゲンシンターゼキナーゼ３のインヒビター
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
KR100443570B1 (ko) * 2001-07-31 2004-08-09 크레아젠 주식회사 재조합 인간 인터루킨-4의 제조방법
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7732451B2 (en) 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
JP2005504043A (ja) 2001-08-10 2005-02-10 パラチン テクノロジーズ インク． 生物学的に活性な金属ペプチド類のペプチド模倣体類
US7354923B2 (en) * 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7655658B2 (en) 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
SE8302886D0 (sv) * 1983-05-20 1983-05-20 Ferrosan Ab Intermediates for preparing substituted 1-piperazine-carboxamides and carbothioamides and use thereof
HU196194B (en) * 1986-04-28 1988-10-28 Richter Gedeon Vegyeszet Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds
NZ223847A (en) * 1987-04-01 1989-12-21 Janssen Pharmaceutica Nv Substituted piperazine derivatives and pharmaceutical compositions
US5026853A (en) * 1987-04-01 1991-06-25 Janssen Pharmaceutica N.V. 4-substituted-2(or 3)aminocarbonyl-1-piperazineacetamide
US4880808A (en) * 1987-04-01 1989-11-14 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for improving sleep
EP0455789B1 (en) * 1989-11-22 1994-03-16 Janssen Pharmaceutica N.V. Method of preventing or limiting reperfusion damage

Also Published As

Publication number Publication date
IL106502A (en) 1997-08-14
DE69328165D1 (de) 2000-04-27
IL106502A0 (en) 1993-11-15
DK0620814T3 (da) 2000-07-17
NZ254312A (en) 1997-06-24
US5574031A (en) 1996-11-12
PT620814E (pt) 2000-09-29
EP0620814B1 (en) 2000-03-22
ES2144009T3 (es) 2000-06-01
AU4595393A (en) 1994-03-03
ATE190973T1 (de) 2000-04-15
AU666212B2 (en) 1996-02-01
WO1994003436A1 (en) 1994-02-17
CN1055687C (zh) 2000-08-23
GR3033629T3 (en) 2000-10-31
SE9202266D0 (sv) 1992-07-31
DE69328165T2 (de) 2000-10-05
JP3418195B2 (ja) 2003-06-16
JPH08508008A (ja) 1996-08-27
EP0620814A1 (en) 1994-10-26
CN1088579A (zh) 1994-06-29
CA2141210A1 (en) 1994-02-17

Similar Documents

Publication Publication Date Title
ZA935534B (en) Piperazine carboxamides
DE69327541D1 (en) 4-arylmethyloxymethyl piperidine als tachykinin antagonisten
GR3034906T3 (en) Indoletetralins having dopaminergic activity
PH31303A (en) Piperazine derivatives.
ES8500887A1 (es) Un procedimiento para la preparacion de nuevos derivados de propanolamina.
NO952610D0 (no) Pyridonkarboksylsyrederivater
MY129935A (en) Dihydropyridine derivatives useful in antitumor therapy
GB2311780B (en) Pharmaceutical Piperazine Compounds
ZA935533B (en) Pyridyl-and pyrimidyl-piperazine derivatives
ES8707498A1 (es) Un procedimiento para preparar derivados de azetidinona
GR3034400T3 (en) Use of piperazine derivatives for the treatment of cognitive disorders
MX9603868A (es) Composicion farmaceutica de derivados de indeno para la regulacion de la apoptosis.
GR3022796T3 (en) Ureido-acetamide derivatives, preparation thereof and drugs containing same.