ZA931876B - 2-Oxoquinoline derivatives - Google Patents

2-Oxoquinoline derivatives

Info

Publication number
ZA931876B
ZA931876B ZA931876A ZA931876A ZA931876B ZA 931876 B ZA931876 B ZA 931876B ZA 931876 A ZA931876 A ZA 931876A ZA 931876 A ZA931876 A ZA 931876A ZA 931876 B ZA931876 B ZA 931876B
Authority
ZA
South Africa
Prior art keywords
oxoquinoline derivatives
oxoquinoline
derivatives
Prior art date
Application number
ZA931876A
Other languages
English (en)
Inventor
Werner Mederski
Norbert Beier
Klaus Otto Minck
Dieter Dorsch
Ingeborg Lues
Pierre Schelling
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA931876B publication Critical patent/ZA931876B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ZA931876A 1992-03-16 1993-03-16 2-Oxoquinoline derivatives ZA931876B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4208304A DE4208304A1 (de) 1992-03-16 1992-03-16 2-oxochinolinderivate

Publications (1)

Publication Number Publication Date
ZA931876B true ZA931876B (en) 1993-10-06

Family

ID=6454136

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA931876A ZA931876B (en) 1992-03-16 1993-03-16 2-Oxoquinoline derivatives

Country Status (14)

Country Link
US (1) US5371226A (xx)
EP (1) EP0561252A1 (xx)
JP (1) JPH0625174A (xx)
KR (1) KR930019631A (xx)
CN (1) CN1077192A (xx)
AU (1) AU663358B2 (xx)
CA (1) CA2092671A1 (xx)
CZ (1) CZ42193A3 (xx)
DE (1) DE4208304A1 (xx)
HU (1) HUT70038A (xx)
MX (1) MX9301404A (xx)
NO (1) NO930926L (xx)
PL (1) PL298080A1 (xx)
ZA (1) ZA931876B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9125485D0 (en) * 1991-11-29 1992-01-29 Merck Sharp & Dohme Therapeutic agents
DE4341453A1 (de) * 1993-12-06 1995-06-08 Merck Patent Gmbh Imidazopyridine
DE19528418A1 (de) * 1995-08-02 1997-02-06 Merck Patent Gmbh Endothelin-Rezeptor-Antagonisten
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
AU4719799A (en) * 1998-06-30 2000-01-17 Du Pont Pharmaceuticals Company Substituted quinolin-2(1h)-ones useful as hiv reverse transcriptase inhibitors
AU767456B2 (en) * 1998-07-06 2003-11-13 Bristol-Myers Squibb Company Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
US6638937B2 (en) 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
DE19839499A1 (de) * 1998-08-29 2000-03-02 Merck Patent Gmbh 2-Oxo-2H-chinolinderivate
EP1198231A1 (en) * 1999-07-21 2002-04-24 American Home Products Corporation Bicyclic antagonists selective for the(alpha)v(beta)3 integrin
US7939545B2 (en) * 2006-05-16 2011-05-10 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
UA100250C2 (uk) 2007-11-16 2012-12-10 Гілеад Сайнсіз, Інк. Інгібітори реплікації вірусу імунодефіциту людини
SG190246A1 (en) * 2010-12-01 2013-06-28 Pfizer Kat ii inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3406329A1 (de) * 1984-02-22 1985-08-22 Merck Patent Gmbh, 6100 Darmstadt Pyridone
US4760064A (en) * 1984-12-18 1988-07-26 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds, compositions containing same and processes for preparing same
US5036048A (en) * 1986-03-07 1991-07-30 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
CA2020073A1 (en) * 1989-07-03 1991-01-04 Eric E. Allen Substituted quinazolinones as angiotensin ii antagonists
US5100897A (en) * 1989-08-28 1992-03-31 Merck & Co., Inc. Substituted pyrimidinones as angiotensin ii antagonists
US5064837A (en) * 1989-11-13 1991-11-12 Schering Corporation 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions
EP0430709A3 (en) * 1989-12-01 1992-02-12 Glaxo Group Limited Benzthiophen derivatives
US5140037A (en) * 1990-03-20 1992-08-18 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with imidazole angiotensin-ii receptor antagonists
CA2051705A1 (en) * 1990-06-19 1991-12-20 Kiyoaki Katano Pyridine derivatives having angiotensin ii antagonism
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
US5283241A (en) * 1992-08-28 1994-02-01 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone
US5284841A (en) * 1993-02-04 1994-02-08 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone

Also Published As

Publication number Publication date
AU663358B2 (en) 1995-10-05
AU3406793A (en) 1993-09-23
PL298080A1 (en) 1993-10-18
CZ42193A3 (en) 1994-01-19
CN1077192A (zh) 1993-10-13
EP0561252A1 (de) 1993-09-22
HU9300744D0 (en) 1993-05-28
DE4208304A1 (de) 1993-09-23
NO930926L (no) 1993-09-17
HUT70038A (en) 1995-09-28
CA2092671A1 (en) 1993-09-17
KR930019631A (ko) 1993-10-18
JPH0625174A (ja) 1994-02-01
US5371226A (en) 1994-12-06
NO930926D0 (no) 1993-03-15
MX9301404A (es) 1993-09-01

Similar Documents

Publication Publication Date Title
PL307812A1 (en) Substituted thiazolydinone derivatives
IL122339A0 (en) Thiohydantoine derivatives
GB9305306D0 (en) Pyrrolo-pyridazione derivatives
HU9400724D0 (en) 2-thio-substituted carbapeneme derivatives
HU9301955D0 (en) Benzophenone-hydrazone derivatives
ZA945504B (en) Benzocarbocyclic derivatives
HU9300744D0 (en) 2-oxo-quinoline derivatives
EP0520435A3 (en) Dc-89 derivatives
HU9301112D0 (en) Propenoyl-imidazole derivatives
HU9301616D0 (en) New thio-semicarbazone derivatives
GB2271564B (en) Thioalkylthio carbacephalosporin derivatives
GB2270913B (en) Chlordifluoromethoxyphenyl derivatives
ZA945589B (en) 2-phenylpyrrole derivatives
ZA947183B (en) 3-aryl-4-hydroxy-Delta3-dihydrofuranone derivatives
ZA931516B (en) Substituted phenylquinazoline derivatives
GB2262739B (en) Benzofuranylimidazole derivatives
ZA947128B (en) Hydroxyethyl-azolyl derivatives
GB9102423D0 (en) Pryimidinyl-and triazinylsalicyl-and-picolinylaldehyde derivatives
EP0565961A3 (en) Ethyl-triazolyl derivatives
ZA945588B (en) 2-Phenylpyrrole derivatives
GB9223244D0 (en) Phenylpyrazine derivatives
HU9302058D0 (en) Thia-diazinone derivatives
GB2274282B (en) Piperazine-and piperidine-isoxazole derivatives
ZA934972B (en) 21-Chloro-pregnane derivative
GB9304440D0 (en) 2-acyloxycephem derivatives