ZA928396B - HIV protease inhibitors. - Google Patents

HIV protease inhibitors.

Info

Publication number
ZA928396B
ZA928396B ZA928396A ZA928396A ZA928396B ZA 928396 B ZA928396 B ZA 928396B ZA 928396 A ZA928396 A ZA 928396A ZA 928396 A ZA928396 A ZA 928396A ZA 928396 B ZA928396 B ZA 928396B
Authority
ZA
South Africa
Prior art keywords
protease inhibitors
hiv protease
hiv
inhibitors
protease
Prior art date
Application number
ZA928396A
Other languages
English (en)
Inventor
John Gerald Cleason
Robert Thomas Lum
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA928396B publication Critical patent/ZA928396B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • AIDS & HIV (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA928396A 1991-11-01 1992-10-30 HIV protease inhibitors. ZA928396B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78643591A 1991-11-01 1991-11-01

Publications (1)

Publication Number Publication Date
ZA928396B true ZA928396B (en) 1993-05-12

Family

ID=25138568

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928396A ZA928396B (en) 1991-11-01 1992-10-30 HIV protease inhibitors.

Country Status (7)

Country Link
EP (1) EP0610431A1 (fr)
JP (1) JPH07501056A (fr)
AU (1) AU3069192A (fr)
MX (1) MX9206294A (fr)
PT (1) PT101026A (fr)
WO (1) WO1993009132A1 (fr)
ZA (1) ZA928396B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430150A (en) * 1992-12-16 1995-07-04 American Cyanamid Company Retroviral protease inhibitors
US5455351A (en) * 1993-12-13 1995-10-03 Abbott Laboratories Retroviral protease inhibiting piperazine compounds
AUPM623994A0 (en) * 1994-06-15 1994-07-07 Biomolecular Research Institute Limited Antiviral dendrimers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3809145A1 (de) * 1988-03-18 1989-09-28 Merck Patent Gmbh Aminosaeurederivate
DE3812328A1 (de) * 1988-04-14 1989-10-26 Merck Patent Gmbh Aminosaeurederivate
IL91307A0 (en) * 1988-08-24 1990-03-19 Merck & Co Inc Hiv protease inhibitors and pharmaceutical compositions for the treatment of aids containing them

Also Published As

Publication number Publication date
EP0610431A1 (fr) 1994-08-17
MX9206294A (es) 1993-08-01
JPH07501056A (ja) 1995-02-02
WO1993009132A1 (fr) 1993-05-13
AU3069192A (en) 1993-06-07
PT101026A (pt) 1994-05-31

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