ZA926783B - Tricyclic heterocycles. - Google Patents

Tricyclic heterocycles.

Info

Publication number
ZA926783B
ZA926783B ZA926783A ZA926783A ZA926783B ZA 926783 B ZA926783 B ZA 926783B ZA 926783 A ZA926783 A ZA 926783A ZA 926783 A ZA926783 A ZA 926783A ZA 926783 B ZA926783 B ZA 926783B
Authority
ZA
South Africa
Prior art keywords
tricyclic heterocycles
methylene
formula
relates
substituents
Prior art date
Application number
ZA926783A
Other languages
English (en)
Inventor
Howard Tucker
John Oldfield
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of ZA926783B publication Critical patent/ZA926783B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA926783A 1991-09-27 1992-09-07 Tricyclic heterocycles. ZA926783B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919120640A GB9120640D0 (en) 1991-09-27 1991-09-27 Tricyclic heterocycles

Publications (1)

Publication Number Publication Date
ZA926783B true ZA926783B (en) 1993-03-29

Family

ID=10702122

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA926783A ZA926783B (en) 1991-09-27 1992-09-07 Tricyclic heterocycles.

Country Status (16)

Country Link
US (1) US5317101A (fr)
EP (1) EP0534667B1 (fr)
JP (1) JPH05230055A (fr)
KR (1) KR930006014A (fr)
AT (1) ATE148700T1 (fr)
AU (1) AU2217992A (fr)
CA (1) CA2078401A1 (fr)
CZ (1) CZ292092A3 (fr)
DE (1) DE69217312T2 (fr)
FI (1) FI924300A (fr)
GB (2) GB9120640D0 (fr)
HU (1) HU9203002D0 (fr)
IL (1) IL103082A0 (fr)
NO (1) NO923736L (fr)
TW (1) TW224972B (fr)
ZA (1) ZA926783B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550122A (en) * 1989-08-29 1996-08-27 Boehringer Ingelheim Pharmaceuticals, Inc. Pyrido[2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and thiones and their use on the treatment of HIV infection
US5304644A (en) * 1992-04-15 1994-04-19 G. D. Searle & Co. 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
US5449673A (en) * 1992-08-13 1995-09-12 G. D. Searle & Co. 10,11-dihydro-10-(3-substituted-1-oxo-2-propyl, propenyl or propynyl)dibenz[b,f][1,4] oxazepine prostaglandin antagonists
US5420123A (en) * 1992-12-21 1995-05-30 Bristol-Myers Squibb Company Dibenzodiazepine endothelin antagonists
US5395932A (en) * 1993-04-30 1995-03-07 G. D. Searle & Co. 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5354746A (en) * 1993-06-01 1994-10-11 G. D. Searle & Co. Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5354747A (en) * 1993-06-16 1994-10-11 G. D. Searle & Co. 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5424424A (en) * 1993-10-07 1995-06-13 G. D. Searle & Co. Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5420270A (en) * 1993-10-07 1995-05-30 G. D. Searle & Co. Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5488046A (en) * 1993-11-03 1996-01-30 G. D. Searle & Co. Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5441950A (en) * 1994-06-09 1995-08-15 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use
US5449675A (en) * 1994-06-09 1995-09-12 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use
GB9514160D0 (en) * 1994-07-25 1995-09-13 Zeneca Ltd Aromatic compounds
GB9417532D0 (en) * 1994-08-31 1994-10-19 Zeneca Ltd Aromatic compounds
GB9420557D0 (en) * 1994-10-12 1994-11-30 Zeneca Ltd Aromatic compounds
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
TW502026B (en) * 1995-06-20 2002-09-11 Zeneca Ltd Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates
TW434240B (en) * 1995-06-20 2001-05-16 Zeneca Ltd Aromatic compounds, preparation thereof and pharmaceutical composition comprising same
US5834468A (en) * 1995-07-07 1998-11-10 Zeneca Limited Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists
DE69707672T2 (de) * 1996-06-07 2002-08-08 F. Hoffmann-La Roche Ag, Basel Dibenzo-oxazepin- und dioxepin-derivate und ihre verwendung als antitumormittel
JP2007531773A (ja) * 2004-03-31 2007-11-08 レキシコン・ジェネティクス・インコーポレーテッド プロテインキナーゼ変調剤としての２−アミノメチルチアゾール−５−カルボキサミド
ES2437323T3 (es) 2007-02-16 2014-01-10 Ono Pharmaceutical Co., Ltd. Agente terapéutico para trastornos de la micción

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL127795C (fr) * 1966-01-28
US3452046A (en) * 1966-04-29 1969-06-24 Squibb & Sons Inc Dibenzoazathiacycloalkane carboxamides and related oxa compounds
US3534019A (en) * 1967-10-30 1970-10-13 Searle & Co Dibenzoxazepine - n - carboxylic acid hydrazides and related compounds
US3624104A (en) * 1969-10-27 1971-11-30 Searle & Co Aralkanoyl derivatives of dibenzoxazepine-n-carboxylic acid hydrazides
US3644346A (en) * 1969-10-27 1972-02-22 Searle & Co Dibenzoxazepine semicarbazones
US3917649A (en) * 1971-03-23 1975-11-04 Searle & Co Dibenzoxazepine N-carboxylic acid hydrazides and derivatives
US3989719A (en) * 1971-03-23 1976-11-02 G. D. Searle & Co. Dibenzoxazepine N-carboxylic acid hydrazides and derivatives
US3992375A (en) * 1974-08-12 1976-11-16 G. D. Searle & Co. Dibenzoxazepine N-carboxylic acid hydrazines and derivatives
GB1522003A (en) * 1975-10-17 1978-08-23 Searle & Co 1-acyl-2-(8-chloro-10,11-dihydrodibenz-(b,f)(1,4)-oxazepine-10-carbonyl)hydrazines
JPS6117663A (ja) * 1984-07-03 1986-01-25 株式会社アイジー技術研究所 内、外壁改修構造
US4728735A (en) * 1984-10-15 1988-03-01 Merck & Co., Inc. 10,11-dihydro-dibenzo-[b,f][1,4]-thiazepin derivatives
US4559337A (en) * 1985-02-25 1985-12-17 G.D. Searle & Co. 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides
US4559336A (en) * 1985-02-25 1985-12-17 G.D. Searle & Co. 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(sulfinyl- and sulfonyl-containing acyl)hydrazides
US4614617A (en) * 1985-02-25 1986-09-30 G. D. Searle & Co. Intermediates for 8-chlorodibenz[(b,f)][1,4]oxazepine-10(11H)-carboxylic acid, 2-(sulfinyl- and sulfonyl-containing acyl)hydrazides
US4704386A (en) * 1985-08-29 1987-11-03 G. D. Searle & Co. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides
JPH04211071A (ja) * 1990-03-05 1992-08-03 Hokuriku Seiyaku Co Ltd 多環式化合物

Also Published As

Publication number Publication date
FI924300A0 (fi) 1992-09-25
FI924300A (fi) 1993-03-28
DE69217312D1 (de) 1997-03-20
US5317101A (en) 1994-05-31
NO923736D0 (no) 1992-09-25
TW224972B (fr) 1994-06-11
DE69217312T2 (de) 1997-05-22
IL103082A0 (en) 1993-02-21
CZ292092A3 (en) 1993-04-14
AU2217992A (en) 1993-04-01
ATE148700T1 (de) 1997-02-15
KR930006014A (ko) 1993-04-20
HU9203002D0 (en) 1992-12-28
NO923736L (no) 1993-03-29
CA2078401A1 (fr) 1993-03-28
EP0534667B1 (fr) 1997-02-05
GB9120640D0 (en) 1991-11-06
EP0534667A1 (fr) 1993-03-31
JPH05230055A (ja) 1993-09-07
GB9220242D0 (en) 1992-11-11

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