ZA921232B - Quinoline-containing ketoacids as leukotriene antagonists - Google Patents
Quinoline-containing ketoacids as leukotriene antagonistsInfo
- Publication number
- ZA921232B ZA921232B ZA921232A ZA921232A ZA921232B ZA 921232 B ZA921232 B ZA 921232B ZA 921232 A ZA921232 A ZA 921232A ZA 921232 A ZA921232 A ZA 921232A ZA 921232 B ZA921232 B ZA 921232B
- Authority
- ZA
- South Africa
- Prior art keywords
- ketoacids
- quinoline
- leukotriene antagonists
- compounds
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65893191A | 1991-02-21 | 1991-02-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA921232B true ZA921232B (en) | 1992-10-28 |
Family
ID=24643302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA921232A ZA921232B (en) | 1991-02-21 | 1992-02-20 | Quinoline-containing ketoacids as leukotriene antagonists |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0500360B1 (fi) |
| JP (1) | JPH0788361B2 (fi) |
| KR (1) | KR920016423A (fi) |
| CN (1) | CN1065062A (fi) |
| AT (1) | ATE154801T1 (fi) |
| AU (1) | AU648385B2 (fi) |
| CA (1) | CA2061675C (fi) |
| CS (1) | CS47192A3 (fi) |
| DE (1) | DE69220517T2 (fi) |
| ES (1) | ES2104821T3 (fi) |
| FI (1) | FI920734A (fi) |
| HU (1) | HU9200552D0 (fi) |
| IE (1) | IE920499A1 (fi) |
| IL (1) | IL100985A0 (fi) |
| MX (1) | MX9200714A (fi) |
| NO (1) | NO920681L (fi) |
| ZA (1) | ZA921232B (fi) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
| GB9216768D0 (en) * | 1992-08-07 | 1992-09-23 | Leo Pharm Prod Ltd | Chemical compounds |
| AU715358B2 (en) * | 1995-04-28 | 2000-01-20 | Takeda Chemical Industries Ltd. | Therapeutic composition for arthritis |
| AU3868497A (en) * | 1996-08-26 | 1998-03-19 | Yamanouchi Pharmaceutical Co., Ltd. | Benzenesulfone compounds and salts thereof |
| ES2159209T3 (es) * | 1998-07-14 | 2001-09-16 | Alcon Lab Inc | Uso de acido 11-(3-dimetilaminopropiliden)-6,11-dihidrodibenz(b,e)oxepin-2-acetico y de sus sales farmaceuticamente aceptables para la fabricacion de un medicamento para el tratamiento de trastornos oftalmicos no alergicos y para la prevencion de neovascularizacion ocular. |
| JP2007532686A (ja) * | 2004-04-21 | 2007-11-15 | テバ ファーマシューティカル インダストリーズ リミティド | モンテルカストナトリウムを調製する方法 |
| ITMI20050247A1 (it) * | 2005-02-18 | 2006-08-19 | Chemi Spa | Processo per la preparazione di montelukast |
| WO2006131782A1 (en) * | 2005-06-07 | 2006-12-14 | Glade Organics Private Limited | Process for the manufacture of methyl-2-(3-(2-(7-chloro-2-quinolinyl-ethenyl)-phenyl)-3-oxopropyl) benzoate |
| CN101213177A (zh) | 2005-07-05 | 2008-07-02 | 特瓦制药工业有限公司 | 孟鲁司特的纯化 |
| AR056815A1 (es) * | 2005-11-18 | 2007-10-24 | Synthon Bv | PROCESO PARA PREPARAR MONTELUKAST, INTERMEDIARIOS DEL MISMO Y SUS SALES DE ADICIoN Y PROCEDIMIENTO DE PURIFICACIoN DE ÉSTOS Y DE MONTELUKAST |
| CN101356157B (zh) * | 2005-11-18 | 2011-07-06 | 斯索恩有限公司 | 制备孟鲁司特及其中间体的方法 |
| NZ575552A (en) * | 2006-09-15 | 2012-02-24 | Cipla Ltd | Process for the preparation of montelukast, and intermediates therefor |
| ES2320077B1 (es) | 2007-07-31 | 2010-02-26 | Moehs Iberica, S.L. | Proceso de preparacion de un antagonista de leucotrienos y de un intermedio del mismo. |
| CN101851196B (zh) * | 2010-05-28 | 2011-07-27 | 中国科学院昆明植物研究所 | 2-(1h)喹啉酮衍生物,其药物组合物及其制备方法和用途 |
| BR112014001760A2 (pt) * | 2011-07-26 | 2017-03-07 | Sun Pharma Advanced Res Co Ltd | antagonistas de leucotrieno cisteínico |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE59889B1 (en) * | 1986-02-14 | 1994-04-20 | Merck Frosst Canada Inc | 2-substituted quinoline dioic acids |
| IL88433A0 (en) * | 1987-11-25 | 1989-06-30 | Merck Frosst Canada Inc | Diarylstyrylquinoline diacids and pharmaceutical compositions containing them |
| EP0349062A1 (en) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Quinoline ether alkanoic acid |
| NZ233752A (en) * | 1989-05-24 | 1993-05-26 | Merck Frosst Canada Inc | Substituted quinoline derivatives, preparation and pharmaceutical compositions thereof |
-
1992
- 1992-02-17 IE IE049992A patent/IE920499A1/en not_active Application Discontinuation
- 1992-02-18 IL IL100985A patent/IL100985A0/xx unknown
- 1992-02-18 CS CS92471A patent/CS47192A3/cs unknown
- 1992-02-20 ZA ZA921232A patent/ZA921232B/xx unknown
- 1992-02-20 NO NO92920681A patent/NO920681L/no unknown
- 1992-02-20 MX MX9200714A patent/MX9200714A/es unknown
- 1992-02-20 AU AU11119/92A patent/AU648385B2/en not_active Ceased
- 1992-02-20 HU HU9200552A patent/HU9200552D0/hu unknown
- 1992-02-20 FI FI920734A patent/FI920734A/fi not_active Application Discontinuation
- 1992-02-20 KR KR1019920002536A patent/KR920016423A/ko not_active Application Discontinuation
- 1992-02-20 DE DE69220517T patent/DE69220517T2/de not_active Expired - Fee Related
- 1992-02-20 CN CN92102076A patent/CN1065062A/zh active Pending
- 1992-02-20 AT AT92301393T patent/ATE154801T1/de not_active IP Right Cessation
- 1992-02-20 ES ES92301393T patent/ES2104821T3/es not_active Expired - Lifetime
- 1992-02-20 EP EP92301393A patent/EP0500360B1/en not_active Expired - Lifetime
- 1992-02-21 JP JP4034632A patent/JPH0788361B2/ja not_active Expired - Lifetime
- 1992-02-21 CA CA002061675A patent/CA2061675C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE920499A1 (en) | 1992-08-26 |
| CA2061675C (en) | 2002-12-17 |
| ES2104821T3 (es) | 1997-10-16 |
| NO920681L (no) | 1992-08-24 |
| FI920734A0 (fi) | 1992-02-20 |
| FI920734A (fi) | 1992-08-22 |
| DE69220517T2 (de) | 1997-12-18 |
| NO920681D0 (no) | 1992-02-20 |
| ATE154801T1 (de) | 1997-07-15 |
| MX9200714A (es) | 1992-10-01 |
| KR920016423A (ko) | 1992-09-24 |
| EP0500360A1 (en) | 1992-08-26 |
| CN1065062A (zh) | 1992-10-07 |
| DE69220517D1 (de) | 1997-07-31 |
| JPH0788361B2 (ja) | 1995-09-27 |
| EP0500360B1 (en) | 1997-06-25 |
| AU648385B2 (en) | 1994-04-21 |
| CA2061675A1 (en) | 1992-08-22 |
| HU9200552D0 (en) | 1992-05-28 |
| CS47192A3 (en) | 1992-10-14 |
| AU1111992A (en) | 1992-08-27 |
| JPH0525135A (ja) | 1993-02-02 |
| IL100985A0 (en) | 1992-11-15 |
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