ZA919438B - Use of xanthines for the preparation of a medicament having immuno supressing activity - Google Patents
Use of xanthines for the preparation of a medicament having immuno supressing activityInfo
- Publication number
- ZA919438B ZA919438B ZA919438A ZA919438A ZA919438B ZA 919438 B ZA919438 B ZA 919438B ZA 919438 A ZA919438 A ZA 919438A ZA 919438 A ZA919438 A ZA 919438A ZA 919438 B ZA919438 B ZA 919438B
- Authority
- ZA
- South Africa
- Prior art keywords
- supressing
- xanthines
- immuno
- medicament
- activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62048090A | 1990-11-30 | 1990-11-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA919438B true ZA919438B (en) | 1992-08-26 |
Family
ID=24486121
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA919438A ZA919438B (en) | 1990-11-30 | 1991-11-29 | Use of xanthines for the preparation of a medicament having immuno supressing activity |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0490181A1 (pt) |
JP (1) | JPH06100450A (pt) |
KR (1) | KR920009399A (pt) |
CA (1) | CA2056723A1 (pt) |
HU (1) | HUT59825A (pt) |
IE (1) | IE914163A1 (pt) |
IL (1) | IL100195A0 (pt) |
PT (1) | PT99659A (pt) |
TW (1) | TW205507B (pt) |
ZA (1) | ZA919438B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU664189B2 (en) * | 1991-05-24 | 1995-11-09 | Fred Hutchinson Cancer Research Center | Modulation of cellular response to external stimuli |
DE4411660A1 (de) * | 1994-04-05 | 1995-10-12 | Hoechst Ag | Verwendung von Xanthinderivaten zur Reduktion der pathologischen Hyperreagibilität eosinophiler Granulozyten, neue Xanthinverbindungen und Verfahren zu deren Herstellung |
DE4430128A1 (de) * | 1994-08-25 | 1996-02-29 | Hoechst Ag | Kombinationspräparat mit immunsuppressiven, kardiovaskulären und cerebralen Wirkungen |
DE4430127A1 (de) * | 1994-08-25 | 1996-03-14 | Hoechst Ag | Kombinationspräparat, enthaltend Cyclosporin A oder FK506 und ein Xanthinderivat |
US6323201B1 (en) | 1994-12-29 | 2001-11-27 | The Regents Of The University Of California | Compounds for inhibition of ceramide-mediated signal transduction |
ATE234099T1 (de) * | 1998-04-24 | 2003-03-15 | Leuven K U Res & Dev | Immununterdrückende effekte von 8 substituierten xanthinderivaten |
US6930101B1 (en) | 1999-05-17 | 2005-08-16 | The Regents Of The University Of California | Thiazolopyrimidines useful as TNFα inhibitors |
US7253176B1 (en) | 2000-05-04 | 2007-08-07 | K.U. Leuven Research & Development | Immunosuppressive effects of 8-substituted xanthine derivatives |
BRPI0908107A2 (pt) | 2008-02-29 | 2019-09-24 | Concert Pharmaceuticals Inc | composto derivado de xantina substituída, composição farmacêutica que compreende esse composto, métodos de tratamento de uma enfermidade ou condição em um paciente com necessidade do mesmo, método de tratamento de enfermidade crônica dos rins, do fígado, relacionada com diabetes e de claudicação intermitente |
US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
EP2473052A4 (en) | 2009-09-02 | 2013-03-20 | Concert Pharmaceuticals Inc | SUBSTITUTED XANTHINE DERIVATIVES |
EP2611807A2 (en) | 2010-09-01 | 2013-07-10 | Concert Pharmaceuticals Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione |
WO2013013052A1 (en) | 2011-07-19 | 2013-01-24 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
US9328113B2 (en) | 2012-04-13 | 2016-05-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
WO2013159006A1 (en) | 2012-04-20 | 2013-10-24 | Concert Pharmaceuticals, Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione |
US9549869B2 (en) | 2012-06-29 | 2017-01-24 | Hill-Rom Canado Respiratory Ltd. | Wearable thorax percussion device |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0063827B1 (fr) * | 1980-05-02 | 1985-08-14 | Societe Des Produits Nestle S.A. | 1-Isopropyl- et 1-isobutyl-3,7-diméthylxanthine comme médicaments |
US4965271A (en) * | 1986-12-31 | 1990-10-23 | Hoechst Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
IL106861A (en) * | 1986-12-31 | 1997-02-18 | Hoechst Roussel Pharma | Pentoxifylline metabolites and pharmaceutical formulations containing them for inhibiting the activity of interleukin-1 and leukocyte-derived cytokines |
GB8918297D0 (en) * | 1989-08-10 | 1989-09-20 | Beecham Group Plc | Novel treatment |
-
1991
- 1991-11-28 IL IL100195A patent/IL100195A0/xx unknown
- 1991-11-28 EP EP91120425A patent/EP0490181A1/en not_active Withdrawn
- 1991-11-29 IE IE416391A patent/IE914163A1/en not_active Application Discontinuation
- 1991-11-29 KR KR1019910021768A patent/KR920009399A/ko not_active Application Discontinuation
- 1991-11-29 HU HU913721A patent/HUT59825A/hu unknown
- 1991-11-29 JP JP3316210A patent/JPH06100450A/ja active Pending
- 1991-11-29 CA CA002056723A patent/CA2056723A1/en not_active Abandoned
- 1991-11-29 PT PT99659A patent/PT99659A/pt not_active Application Discontinuation
- 1991-11-29 ZA ZA919438A patent/ZA919438B/xx unknown
-
1992
- 1992-03-06 TW TW081101708A patent/TW205507B/zh active
Also Published As
Publication number | Publication date |
---|---|
JPH06100450A (ja) | 1994-04-12 |
HU913721D0 (en) | 1992-02-28 |
KR920009399A (ko) | 1992-06-25 |
CA2056723A1 (en) | 1992-05-31 |
EP0490181A1 (en) | 1992-06-17 |
TW205507B (pt) | 1993-05-11 |
IE914163A1 (en) | 1992-06-03 |
HUT59825A (en) | 1992-07-28 |
IL100195A0 (en) | 1992-08-18 |
PT99659A (pt) | 1992-10-30 |
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