ZA919196B - New and useful excitatory amino acid antagonist - Google Patents
New and useful excitatory amino acid antagonistInfo
- Publication number
- ZA919196B ZA919196B ZA919196A ZA919196A ZA919196B ZA 919196 B ZA919196 B ZA 919196B ZA 919196 A ZA919196 A ZA 919196A ZA 919196 A ZA919196 A ZA 919196A ZA 919196 B ZA919196 B ZA 919196B
- Authority
- ZA
- South Africa
- Prior art keywords
- amino acid
- excitatory amino
- useful
- new
- acid antagonist
- Prior art date
Links
- 239000003194 amino acid receptor blocking agent Substances 0.000 title abstract 2
- 102000018899 Glutamate Receptors Human genes 0.000 abstract 1
- 108010027915 Glutamate Receptors Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/383—Cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62416890A | 1990-12-07 | 1990-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA919196B true ZA919196B (en) | 1992-09-30 |
Family
ID=24500939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA919196A ZA919196B (en) | 1990-12-07 | 1991-11-20 | New and useful excitatory amino acid antagonist |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0639197B1 (OSRAM) |
| JP (1) | JP2721933B2 (OSRAM) |
| AT (1) | ATE142220T1 (OSRAM) |
| CA (1) | CA2097910A1 (OSRAM) |
| DE (1) | DE69121920T2 (OSRAM) |
| DK (1) | DK0639197T3 (OSRAM) |
| ES (1) | ES2094338T3 (OSRAM) |
| GR (1) | GR3021881T3 (OSRAM) |
| IE (1) | IE75735B1 (OSRAM) |
| WO (1) | WO1992010099A1 (OSRAM) |
| ZA (1) | ZA919196B (OSRAM) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6028213A (en) | 1998-04-16 | 2000-02-22 | Eastman Chemical Company | Optically active cis-1,3-cyclohexanedicarboxylic acid monoesters with high enantiomeric purity and process for their preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761405A (en) | 1987-03-04 | 1988-08-02 | Nova Pharmaceutical Corporation | Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency |
-
1991
- 1991-11-20 ZA ZA919196A patent/ZA919196B/xx unknown
- 1991-12-04 DE DE69121920T patent/DE69121920T2/de not_active Expired - Fee Related
- 1991-12-04 AT AT92901599T patent/ATE142220T1/de not_active IP Right Cessation
- 1991-12-04 EP EP92901599A patent/EP0639197B1/en not_active Expired - Lifetime
- 1991-12-04 ES ES92901599T patent/ES2094338T3/es not_active Expired - Lifetime
- 1991-12-04 JP JP4502346A patent/JP2721933B2/ja not_active Expired - Lifetime
- 1991-12-04 CA CA002097910A patent/CA2097910A1/en not_active Abandoned
- 1991-12-04 WO PCT/US1991/008834 patent/WO1992010099A1/en not_active Ceased
- 1991-12-04 DK DK92901599.8T patent/DK0639197T3/da active
- 1991-12-06 IE IE425691A patent/IE75735B1/en not_active IP Right Cessation
-
1996
- 1996-12-04 GR GR960403296T patent/GR3021881T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0639197A1 (en) | 1995-02-22 |
| IE914256A1 (en) | 1992-06-17 |
| EP0639197B1 (en) | 1996-09-04 |
| DE69121920D1 (de) | 1996-10-10 |
| GR3021881T3 (en) | 1997-03-31 |
| JP2721933B2 (ja) | 1998-03-04 |
| WO1992010099A1 (en) | 1992-06-25 |
| JPH06505966A (ja) | 1994-07-07 |
| CA2097910A1 (en) | 1992-06-08 |
| ATE142220T1 (de) | 1996-09-15 |
| ES2094338T3 (es) | 1997-01-16 |
| IE75735B1 (en) | 1997-09-24 |
| DK0639197T3 (OSRAM) | 1997-02-24 |
| EP0639197A4 (en) | 1994-02-21 |
| DE69121920T2 (de) | 1997-04-03 |
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