ZA913091B - Process for the production of aqueous liposome suspensions containing active ingredients - Google Patents

Process for the production of aqueous liposome suspensions containing active ingredients

Info

Publication number
ZA913091B
ZA913091B ZA913091A ZA913091A ZA913091B ZA 913091 B ZA913091 B ZA 913091B ZA 913091 A ZA913091 A ZA 913091A ZA 913091 A ZA913091 A ZA 913091A ZA 913091 B ZA913091 B ZA 913091B
Authority
ZA
South Africa
Prior art keywords
active ingredients
containing active
suspensions containing
production
aqueous phase
Prior art date
Application number
ZA913091A
Inventor
Georg Roessling
Roessling Georg
Andreas Sachse
Sachse Andreas
Hans-Joachim Schroeter
Schroeter Hans-Joachim
Claudia Sprenger
Sprenger Claudia
Cornelia Wawretschek
Wawretschek Cornelia
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6405285&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA913091(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA913091B publication Critical patent/ZA913091B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Described is a process for the preparation of aqueous liposome suspensions containing active substances, the suspensions being prepared from a solution of a liposome-forming substance, or mixture of such substances, in a lower alcohol with a maximum of three carbon atoms and an aqueous phase, the active ingredients being dissolved or suspended in the lipid solution and/or the aqueous phase. The process is characterized in that the aqueous phase is incorporated, by mixing, in the alcoholic solution and the lower alcohol removed by vacuum distillation and, if necessary, the liposome suspension freeze-dried.
ZA913091A 1990-04-24 1991-04-24 Process for the production of aqueous liposome suspensions containing active ingredients ZA913091B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4013580A DE4013580A1 (en) 1990-04-24 1990-04-24 METHOD FOR THE PRODUCTION OF ACTIVE AQUEOUS LIPOSOME SUSPENSIONS

Publications (1)

Publication Number Publication Date
ZA913091B true ZA913091B (en) 1992-12-30

Family

ID=6405285

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913091A ZA913091B (en) 1990-04-24 1991-04-24 Process for the production of aqueous liposome suspensions containing active ingredients

Country Status (15)

Country Link
EP (1) EP0478727B1 (en)
JP (1) JPH04506814A (en)
AT (1) ATE141503T1 (en)
AU (1) AU651969B2 (en)
CA (1) CA2041075A1 (en)
DE (2) DE4013580A1 (en)
DK (1) DK0478727T3 (en)
ES (1) ES2093701T3 (en)
FI (1) FI103178B (en)
HU (1) HU215960B (en)
IE (1) IE911350A1 (en)
NO (1) NO303481B1 (en)
PT (1) PT97468B (en)
WO (1) WO1991016039A1 (en)
ZA (1) ZA913091B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3299745B2 (en) * 1991-06-18 2002-07-08 イマアーレクス・フアーマシユーチカル・コーポレーシヨン New liposome drug delivery system
WO1995004523A1 (en) * 1993-08-06 1995-02-16 Opperbas Holding B.V. A method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers
DE69527194T2 (en) * 1994-03-28 2003-02-06 Daiichi Pharmaceutical Co., Ltd. LIPOSOME CONTAINING AN X-RAY OR ULTRASONIC CONTRAST
US6120795A (en) * 1996-03-27 2000-09-19 Ortho Pharmaceutical Corp. Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation
HUP0200421A3 (en) * 1999-02-08 2005-04-28 Alza Corp Mountain View Liposomes of controlled size and method for their preparation
DK1519714T3 (en) * 2002-06-28 2011-01-31 Protiva Biotherapeutics Inc Method and apparatus for preparing liposomes
US9005654B2 (en) 2005-07-27 2015-04-14 Protiva Biotherapeutics, Inc. Systems and methods for manufacturing liposomes
CN114344291B (en) * 2022-02-16 2023-09-29 中南大学湘雅医院 Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3416978A1 (en) * 1983-05-12 1984-12-06 Stauffer Chemical Co., Westport, Conn. TRANSFORMATION OF EUKARYOTIC CELLS MEDIATED BY LIPOSOME
JPS607932A (en) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd Preparation of liposome
EP0158441B2 (en) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposome-forming composition
FR2634375B3 (en) * 1988-06-30 1991-07-05 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF DISPERSIBLE COLLOIDAL LIPID AMPHIPHILIC SYSTEMS IN THE FORM OF SUBMICRON LIPOSOMES
JP2554880B2 (en) * 1987-05-07 1996-11-20 ポーラ化成工業株式会社 Skin cosmetics

Also Published As

Publication number Publication date
ATE141503T1 (en) 1996-09-15
EP0478727B1 (en) 1996-08-21
FI916120A0 (en) 1991-12-23
HU9200235D0 (en) 1992-04-28
FI103178B1 (en) 1999-05-14
EP0478727A1 (en) 1992-04-08
DE4013580A1 (en) 1991-10-31
AU7593391A (en) 1991-11-07
NO915012L (en) 1991-12-18
CA2041075A1 (en) 1991-10-25
HUT62457A (en) 1993-05-28
DE59108097D1 (en) 1996-09-26
DK0478727T3 (en) 1997-01-20
FI103178B (en) 1999-05-14
NO303481B1 (en) 1998-07-20
PT97468A (en) 1992-01-31
HU215960B (en) 1999-03-29
JPH04506814A (en) 1992-11-26
NO915012D0 (en) 1991-12-18
ES2093701T3 (en) 1997-01-01
AU651969B2 (en) 1994-08-11
WO1991016039A1 (en) 1991-10-31
IE911350A1 (en) 1991-11-06
PT97468B (en) 1999-12-31

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