DK0478727T3 - - Google Patents

Info

Publication number
DK0478727T3
DK0478727T3 DK91906756.1T DK91906756T DK0478727T3 DK 0478727 T3 DK0478727 T3 DK 0478727T3 DK 91906756 T DK91906756 T DK 91906756T DK 0478727 T3 DK0478727 T3 DK 0478727T3
Authority
DK
Denmark
Prior art keywords
aqueous phase
liposome
solution
lower alcohol
substances
Prior art date
Application number
DK91906756.1T
Other languages
Danish (da)
Inventor
Andreas Sachse
Georg Dr. Roessling
Hans-Joachim Schroeter
Claudia Sprenger
Cornelia Wawretschek
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6405285&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0478727(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0478727T3 publication Critical patent/DK0478727T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Abstract

Described is a process for the preparation of aqueous liposome suspensions containing active substances, the suspensions being prepared from a solution of a liposome-forming substance, or mixture of such substances, in a lower alcohol with a maximum of three carbon atoms and an aqueous phase, the active ingredients being dissolved or suspended in the lipid solution and/or the aqueous phase. The process is characterized in that the aqueous phase is incorporated, by mixing, in the alcoholic solution and the lower alcohol removed by vacuum distillation and, if necessary, the liposome suspension freeze-dried.
DK91906756.1T 1990-04-24 1991-04-04 DK0478727T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4013580A DE4013580A1 (en) 1990-04-24 1990-04-24 METHOD FOR THE PRODUCTION OF ACTIVE AQUEOUS LIPOSOME SUSPENSIONS

Publications (1)

Publication Number Publication Date
DK0478727T3 true DK0478727T3 (en) 1997-01-20

Family

ID=6405285

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91906756.1T DK0478727T3 (en) 1990-04-24 1991-04-04

Country Status (15)

Country Link
EP (1) EP0478727B1 (en)
JP (1) JPH04506814A (en)
AT (1) ATE141503T1 (en)
AU (1) AU651969B2 (en)
CA (1) CA2041075A1 (en)
DE (2) DE4013580A1 (en)
DK (1) DK0478727T3 (en)
ES (1) ES2093701T3 (en)
FI (1) FI103178B1 (en)
HU (1) HU215960B (en)
IE (1) IE911350A1 (en)
NO (1) NO303481B1 (en)
PT (1) PT97468B (en)
WO (1) WO1991016039A1 (en)
ZA (1) ZA913091B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233119T2 (en) * 1991-06-18 2004-05-13 Imarx Pharmaceutical Corp., Tucson NEW LIPOSOMAL DRUG RELEASE SYSTEMS
ES2113119T3 (en) * 1993-08-06 1998-04-16 Opperbas Holding Bv A METHOD FOR THE PREPARATION OF VESICLES LOADED WITH BIOLOGICAL STRUCTURES, BIOPOLYMERS AND / OR OLIGOMERS.
CN1148812A (en) * 1994-03-28 1997-04-30 尼科梅德成像有限公司 Liposomes
US6120795A (en) * 1996-03-27 2000-09-19 Ortho Pharmaceutical Corp. Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation
ES2225094T3 (en) * 1999-02-08 2005-03-16 Alza Corporation PROCEDURE FOR CONTROLLING THE SIZE OF LIPOSOMES.
JP4722481B2 (en) 2002-06-28 2011-07-13 プロティバ バイオセラピューティクス リミテッド Liposome production method and apparatus
CN101267805A (en) 2005-07-27 2008-09-17 普洛体维生物治疗公司 Systems and methods for manufacturing liposomes
CN114344291B (en) * 2022-02-16 2023-09-29 中南大学湘雅医院 Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3416978A1 (en) * 1983-05-12 1984-12-06 Stauffer Chemical Co., Westport, Conn. TRANSFORMATION OF EUKARYOTIC CELLS MEDIATED BY LIPOSOME
JPS607932A (en) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd Preparation of liposome
DE3585967D1 (en) * 1984-03-08 1992-06-11 Phares Pharma Holland LIPOSOME FORMING COMPOSITION.
FR2634375B3 (en) * 1988-06-30 1991-07-05 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF DISPERSIBLE COLLOIDAL LIPID AMPHIPHILIC SYSTEMS IN THE FORM OF SUBMICRON LIPOSOMES
JP2554880B2 (en) * 1987-05-07 1996-11-20 ポーラ化成工業株式会社 Skin cosmetics

Also Published As

Publication number Publication date
NO915012L (en) 1991-12-18
PT97468B (en) 1999-12-31
PT97468A (en) 1992-01-31
EP0478727A1 (en) 1992-04-08
HUT62457A (en) 1993-05-28
CA2041075A1 (en) 1991-10-25
AU7593391A (en) 1991-11-07
DE4013580A1 (en) 1991-10-31
NO303481B1 (en) 1998-07-20
FI916120A0 (en) 1991-12-23
EP0478727B1 (en) 1996-08-21
HU9200235D0 (en) 1992-04-28
ES2093701T3 (en) 1997-01-01
HU215960B (en) 1999-03-29
ATE141503T1 (en) 1996-09-15
AU651969B2 (en) 1994-08-11
DE59108097D1 (en) 1996-09-26
FI103178B (en) 1999-05-14
IE911350A1 (en) 1991-11-06
NO915012D0 (en) 1991-12-18
JPH04506814A (en) 1992-11-26
ZA913091B (en) 1992-12-30
FI103178B1 (en) 1999-05-14
WO1991016039A1 (en) 1991-10-31

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