ES8707859A1 - A liposomal sustained-release aerosol delivery system. - Google Patents

A liposomal sustained-release aerosol delivery system.

Info

Publication number
ES8707859A1
ES8707859A1 ES547059A ES547059A ES8707859A1 ES 8707859 A1 ES8707859 A1 ES 8707859A1 ES 547059 A ES547059 A ES 547059A ES 547059 A ES547059 A ES 547059A ES 8707859 A1 ES8707859 A1 ES 8707859A1
Authority
ES
Spain
Prior art keywords
delivery system
aerosol delivery
liposomes
drug molecules
release aerosol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547059A
Other languages
Spanish (es)
Other versions
ES547059A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of ES547059A0 publication Critical patent/ES547059A0/en
Publication of ES8707859A1 publication Critical patent/ES8707859A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

A process for the preparation of liposomes which comprises spraying micro-fine droplets of a composition comprising substantially pure phospholipid in a volatile liquid carrier to impinge either upon or below an aqueous surface thereby forming liposomes at the said surface. The compositions may include drug molecules dissolved therein which are entrapped upon formation of the liposomes. The entrapment of drug molecules in this manner provides a method of sustained release of drug molecules.
ES547059A 1984-09-17 1985-09-17 A liposomal sustained-release aerosol delivery system. Expired ES8707859A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848423436A GB8423436D0 (en) 1984-09-17 1984-09-17 Preparation of liposomes

Publications (2)

Publication Number Publication Date
ES547059A0 ES547059A0 (en) 1987-09-01
ES8707859A1 true ES8707859A1 (en) 1987-09-01

Family

ID=10566831

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547059A Expired ES8707859A1 (en) 1984-09-17 1985-09-17 A liposomal sustained-release aerosol delivery system.

Country Status (9)

Country Link
EP (1) EP0195809A1 (en)
JP (1) JPS62500643A (en)
AU (1) AU4866885A (en)
CA (1) CA1256801A (en)
ES (1) ES8707859A1 (en)
GB (1) GB8423436D0 (en)
NZ (1) NZ213459A (en)
WO (1) WO1986001714A1 (en)
ZA (1) ZA856969B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3365744D1 (en) * 1982-01-22 1986-10-09 Fisons Plc Liposome and sodium cromoglycate compositions, and methods for their preparation
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
US5340587A (en) * 1985-05-22 1994-08-23 Liposome Technology, Inc. Liposome/bronchodilator method & System
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
AU587472B2 (en) * 1985-05-22 1989-08-17 Liposome Technology, Inc. Liposome inhalation method and system
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol
SE8601457D0 (en) * 1986-04-01 1986-04-01 Draco Ab COMPOSITIONS OF LIPOSOMES AND B? 712 RECEPTOR ACTIVE SUBSTANCES FOR INHALATION
JP2765700B2 (en) * 1986-08-11 1998-06-18 イノベータ・バイオメド・リミテツド Pharmaceutical composition containing microcapsules
IE63869B1 (en) * 1986-11-06 1995-06-14 Res Dev Foundation Aerosols containing liposomes and method for their preparation
US5049388A (en) * 1986-11-06 1991-09-17 Research Development Foundation Small particle aerosol liposome and liposome-drug combinations for medical use
EP0293465B1 (en) * 1986-11-28 1992-03-18 The Liposome Company, Inc. Phospholipid composition
DE3733652A1 (en) * 1987-10-05 1989-04-20 Abnoba Heilmittel Gmbh METHOD AND DEVICE FOR PRODUCING AQUEOUS COLLOIDS
LU87449A1 (en) * 1989-02-09 1990-09-19 Oreal PROCESS FOR THE MANUFACTURE OF FOAMS FOR USE IN THE COSMETIC AND PHARMACEUTICAL AREAS AND FOAMS OBTAINED BY THIS PROCESS
US5554382A (en) * 1993-05-28 1996-09-10 Aphios Corporation Methods and apparatus for making liposomes
EP0706374B1 (en) * 1993-06-30 1997-12-10 Genentech, Inc. Method for preparing liposomes
EP2227085A4 (en) * 2007-12-06 2013-10-09 Berg Pharma Llc Inhalable compositions having enhanced bioavailability
SG10202010355PA (en) 2010-03-12 2020-11-27 Berg Llc Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
EA201490047A1 (en) 2011-06-17 2014-08-29 Берг Ллк INHALATION PHARMACEUTICAL COMPOSITIONS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
FR2521565B1 (en) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian PULVERULENT MIXTURE OF LIPID COMPONENTS AND HYDROPHOBIC CONSTITUENTS, METHOD FOR PREPARING SAME, HYDRATED LIPID LAMELLAR PHASES AND MANUFACTURING METHOD, PHARMACEUTICAL OR COSMETIC COMPOSITIONS COMPRISING HYDRATED LAMID PHASES
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions

Also Published As

Publication number Publication date
NZ213459A (en) 1989-07-27
AU4866885A (en) 1986-04-08
EP0195809A1 (en) 1986-10-01
WO1986001714A1 (en) 1986-03-27
CA1256801A (en) 1989-07-04
GB8423436D0 (en) 1984-10-24
JPS62500643A (en) 1987-03-19
ES547059A0 (en) 1987-09-01
ZA856969B (en) 1987-06-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519