ZA912402B - Bicyclo(3.3.0)octane derivatives,process for their production and their pharmaceutical use - Google Patents

Bicyclo(3.3.0)octane derivatives,process for their production and their pharmaceutical use

Info

Publication number
ZA912402B
ZA912402B ZA912402A ZA912402A ZA912402B ZA 912402 B ZA912402 B ZA 912402B ZA 912402 A ZA912402 A ZA 912402A ZA 912402 A ZA912402 A ZA 912402A ZA 912402 B ZA912402 B ZA 912402B
Authority
ZA
South Africa
Prior art keywords
bicyclo
production
pharmaceutical use
compounds
octane derivatives
Prior art date
Application number
ZA912402A
Other languages
English (en)
Inventor
Ulrich Klar
Klar Ulrich
Helmut Vorbrueggen
Vorbrueggen Helmut
Peter Verhallen
Verhallen Peter
Hartmut Rehwinkel
Rehwinkel Hartmut
Karl-Heinz Thierauch
Thierauch Karl-Heinz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA912402B publication Critical patent/ZA912402B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ZA912402A 1990-03-28 1991-03-28 Bicyclo(3.3.0)octane derivatives,process for their production and their pharmaceutical use ZA912402B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4010355A DE4010355A1 (de) 1990-03-28 1990-03-28 Bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
ZA912402B true ZA912402B (en) 1992-04-29

Family

ID=6403459

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912402A ZA912402B (en) 1990-03-28 1991-03-28 Bicyclo(3.3.0)octane derivatives,process for their production and their pharmaceutical use

Country Status (17)

Country Link
US (1) US5716989A (fr)
EP (1) EP0474817B1 (fr)
JP (1) JPH05502033A (fr)
AT (1) ATE128966T1 (fr)
AU (1) AU641237B2 (fr)
CA (1) CA2058922A1 (fr)
DE (2) DE4010355A1 (fr)
DK (1) DK0474817T3 (fr)
ES (1) ES2082202T3 (fr)
GR (1) GR3018560T3 (fr)
HU (1) HUT60244A (fr)
IE (1) IE69970B1 (fr)
IL (1) IL97706A (fr)
NZ (1) NZ237605A (fr)
PT (1) PT97205B (fr)
WO (1) WO1991014675A1 (fr)
ZA (1) ZA912402B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070014845A1 (en) * 2005-07-01 2007-01-18 Yuanpeng Zhang Liposomal delivery vehicle for hydrophobic drugs
US20070055199A1 (en) * 2005-08-10 2007-03-08 Gilbert Scott J Drug delivery device for buccal and aural applications and other areas of the body difficult to access

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2845770A1 (de) * 1978-10-19 1980-04-30 Schering Ag Neue prostacyclin-derivate und verfahren zu ihrer herstellung
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4754055A (en) * 1985-03-18 1988-06-28 G. D. Searle & Co. Allenic prostacyclins
NZ218881A (en) * 1986-01-16 1989-05-29 Nat Res Dev Prostaglandin derivatives and analogues as pharmaceuticals
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten

Also Published As

Publication number Publication date
ATE128966T1 (de) 1995-10-15
AU641237B2 (en) 1993-09-16
DE59106666D1 (de) 1995-11-16
HU913693D0 (en) 1992-07-28
GR3018560T3 (en) 1996-03-31
CA2058922A1 (fr) 1991-09-29
AU7543591A (en) 1991-10-21
IL97706A (en) 1995-10-31
DE4010355A1 (de) 1991-10-02
ES2082202T3 (es) 1996-03-16
IL97706A0 (en) 1992-06-21
DK0474817T3 (da) 1996-02-26
EP0474817A1 (fr) 1992-03-18
PT97205B (pt) 1998-07-31
JPH05502033A (ja) 1993-04-15
WO1991014675A1 (fr) 1991-10-03
HUT60244A (en) 1992-08-28
IE69970B1 (en) 1996-10-16
EP0474817B1 (fr) 1995-10-11
NZ237605A (en) 1994-04-27
PT97205A (pt) 1991-11-29
US5716989A (en) 1998-02-10
IE911036A1 (en) 1991-10-09

Similar Documents

Publication Publication Date Title
EP0356399A3 (fr) Dérivés substitués du 4-azatricyclo (22.3.1.04.9) octacos-18-ène, leur préparation et les compositions pharmaceutiques les contenant
TWI224595B (en) New benzazepine derivatives, drugs containing these and use of the same for producing drugs
CA2258548A1 (fr) Derives tricycliques substitues par phenylamino, destines au traitement des maladies hyperproliferatives
YU70901A (sh) Derivati 1,4-benzotiazepin-1,1 dioksida zamenjeni radikalima šećera, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena
BG103417A (en) Condensed pyrimidine bicyclic derivatives
IL112622A (en) Iminoalkylamino or aminoalkylideneamino camptothecin derivatives, process for their preparation and pharmaceutical compositions containing them
MX9503529A (es) Derivados de glicinamida, procedimiento para su preparacion y medicamentos que los contienen.
IL118366A0 (en) Vitamin D derivatives a process for the preparation thereof and pharmaceutical compositions containing the same
ES8606282A1 (es) Un procedimiento de preparar derivados de acidos quinolin- ynaftiridin-carboxilicos
MXPA02009643A (es) Sintesis acortada de derivados de 3,3-diarilpropilamina.
IL112020A0 (en) Arylacetic acid derivatives, their preparation and their use as fungicides
AU7581394A (en) Galanthamine derivatives, a process for their preparation and their use as medicaments
CA2155323A1 (fr) Nouvelle utilisation de composes bis-heterocycliques comme agents anti-inflammatoires; compositions pharmaceutiques de ces agents
IL112098A0 (en) Sulfamate derivatives and pharmaceutical compositions containing them
DE59203771D1 (de) 9-substituierte bicyclo [3.3.0]octan-derivate verwendbar als txa2-antagonisten.
BG103260A (en) The application of 1-hydroxy-2-pyridons for the treatment of seborrheic dermatitis
ZA912402B (en) Bicyclo(3.3.0)octane derivatives,process for their production and their pharmaceutical use
HUT60275A (en) Process for producing 7-acyl-3-(substituted carbamoyloxy)-cef-3-em-4-carboxylic acid derivatives and pharmaceutical compositions comprising such compounds
CA2127374A1 (fr) Nouveau derive de l'isoindolinone, sa preparation et les compositions pharmaceutiques qui le contiennent
IE893258L (en) New 2-carbonyl substituted n,n'-di-(trimethoxybenzoyl)¹piperazines, process for preparing the same and¹therapeutical compounds containing them
EP0189916A3 (fr) Dérivés de 3-(pyrrolidinio)méthyl-3-céphem, composition pharmaceutique et procédé pour leur préparation
HU9203928D0 (en) 6-sulfonyl-substituted 3-hydroxi-chromane derivatives and pharmaceutical preparatives containing them
HUT57227A (en) 2'-dezamino-4'-desoxy-4'-amino-8-fluoro-anthracycline derivatives, process for producing them as well as pharmaceutical preparatives containing said compounds as active substance
AU1866192A (en) New process for the synthesis of enantiomers of 3-aminochroman compounds
HU9600300D0 (en) Thiocarbamoyl derivatives using as antimicrobial agents and process for producing of these