ZA911396B - Propanamines,their pharmacological properties and their application for therapeutic,in particular antidiarrhoeal,purposes - Google Patents

Propanamines,their pharmacological properties and their application for therapeutic,in particular antidiarrhoeal,purposes

Info

Publication number
ZA911396B
ZA911396B ZA911396A ZA911396A ZA911396B ZA 911396 B ZA911396 B ZA 911396B ZA 911396 A ZA911396 A ZA 911396A ZA 911396 A ZA911396 A ZA 911396A ZA 911396 B ZA911396 B ZA 911396B
Authority
ZA
South Africa
Prior art keywords
propanamines
radical
antidiarrhoeal
therapeutic
purposes
Prior art date
Application number
ZA911396A
Other languages
English (en)
Inventor
Alain Calvet
Calvet Alain
Agnes Grouhel
Grouhel Agnes
Henri Jacobelli
Jacobelli Henri
Jean-Louis Junien
Junien Jean-Louis
Xavier Pascaud
Pascaud Xavier
Original Assignee
Jouveinal Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal Sa filed Critical Jouveinal Sa
Publication of ZA911396B publication Critical patent/ZA911396B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/01—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to acyclic carbon atoms
    • C07C205/03—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C205/04—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/08—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to acyclic carbon atoms
    • C07C205/09—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/72—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
ZA911396A 1990-02-28 1991-02-26 Propanamines,their pharmacological properties and their application for therapeutic,in particular antidiarrhoeal,purposes ZA911396B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909002495A FR2658821B1 (fr) 1990-02-28 1990-02-28 Nouvelles propanamines, leurs proprietes pharmacologiques et leur application a des fins therapeutiques, notamment antidiarrheuiques.

Publications (1)

Publication Number Publication Date
ZA911396B true ZA911396B (en) 1992-05-27

Family

ID=9394222

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA911396A ZA911396B (en) 1990-02-28 1991-02-26 Propanamines,their pharmacological properties and their application for therapeutic,in particular antidiarrhoeal,purposes

Country Status (16)

Country Link
US (1) US5143938A (de)
EP (1) EP0450995B1 (de)
JP (1) JPH05320103A (de)
KR (1) KR910021364A (de)
AT (1) ATE106881T1 (de)
AU (1) AU632398B2 (de)
CA (1) CA2037084A1 (de)
DE (1) DE69102335D1 (de)
FI (1) FI910924A (de)
FR (1) FR2658821B1 (de)
HU (1) HUT62282A (de)
IE (1) IE910621A1 (de)
IL (1) IL97357A0 (de)
NZ (1) NZ237228A (de)
PT (1) PT96886A (de)
ZA (1) ZA911396B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
WO1997000872A1 (en) * 1995-06-23 1997-01-09 F.Hoffmann-La Roche Ag 1,3,8-triaza- and 3,8-diaza-1-oxaspiro(4,5)decane derivatives
US5739336A (en) * 1995-06-23 1998-04-14 Syntex (U.S.A.) Inc. 1,3,8-triaza- and 3,8-diaza-1-oxaspiro 4,5! decane derivatives
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
WO2007005644A2 (en) * 2005-07-01 2007-01-11 Concert Pharmaceuticals Inc. Novel aryloxypropanamines
WO2007062119A1 (en) * 2005-11-23 2007-05-31 Auspex Pharmaceuticals, Inc. Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity
MX2011000637A (es) 2008-07-15 2011-05-02 Theracos Inc Derivados deuretados de bencilbenceno y metodos de uso.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB777794A (en) * 1954-09-10 1957-06-26 Thomae Gmbh Dr K New 1:3-dioxolane derivatives and process for their preparation
US3182084A (en) * 1961-09-06 1965-05-04 Bristol Myers Co Amino ketones and their method of preparation
CH539051A (de) * 1970-11-06 1973-08-31 Sandoz Ag Verfahren zur Herstellung von 1-Alkyl-4,6-diphenylpyrimidin-2(1H)-onen
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
CH617434A5 (en) * 1973-12-21 1980-05-30 Hoffmann La Roche Process for the preparation of sulphur-containing heterocyclic compounds
JPS6393753A (ja) * 1986-10-09 1988-04-25 Nippon Kayaku Co Ltd プロピオフエノン誘導体
FR2641276B1 (fr) * 1988-12-30 1991-07-12 Sanofi Sa Derives du benzene, leur preparation et les compositions pharmaceutiques en contenant
JP2861274B2 (ja) * 1989-06-06 1999-02-24 武田薬品工業株式会社 アミノケトン誘導体

Also Published As

Publication number Publication date
EP0450995A1 (de) 1991-10-09
FI910924A0 (fi) 1991-02-26
IE910621A1 (en) 1991-08-28
NZ237228A (en) 1992-05-26
DE69102335D1 (de) 1994-07-14
AU7134191A (en) 1991-08-29
CA2037084A1 (en) 1991-08-29
ATE106881T1 (de) 1994-06-15
HU910626D0 (en) 1991-09-30
PT96886A (pt) 1991-10-31
IL97357A0 (en) 1992-05-25
FR2658821A1 (fr) 1991-08-30
KR910021364A (ko) 1991-12-20
HUT62282A (en) 1993-04-28
AU632398B2 (en) 1992-12-24
FR2658821B1 (fr) 1994-09-16
EP0450995B1 (de) 1994-06-08
US5143938A (en) 1992-09-01
JPH05320103A (ja) 1993-12-03
FI910924A (fi) 1991-08-29

Similar Documents

Publication Publication Date Title
SE8504291D0 (sv) Aromatiska heterocykliska derivat och deras anvendning inom det terapeutiska och kosmetiska omradet
NO892058L (no) Fremgangsmaate for fremstilling av terapeutisk aktive benzamider.
DK499088A (da) 1-oe(2-pyrimidinyl)-aminoalkylaapiperidinderivater, fremgangsmaade til fremstilling deraf og laegemiddel indeholdende saadanne derivater
ZA911396B (en) Propanamines,their pharmacological properties and their application for therapeutic,in particular antidiarrhoeal,purposes
NZ230490A (en) Disubstituted n-cycloalkylalkyl benzylamine derivatives and medicinal preparations
NZ218243A (en) B-carboline derivatives and pharmaceutical compositions
NO164351C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
DK138488A (da) Imidazolderivater
JPS6461466A (en) Derivatives of ureylene, 2,4-triminopyrimidine- 3-oxide, preparation and use for cosmetic and pharmacological composition
ZA893474B (en) Sulphur-containing eicosanoides and their application in pharmacy and in cosmetics
ES2057802T3 (es) Nuevos derivados de 3-amino-cromano, procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ATE127451T1 (de) 3,4-disubstituierte phenyl-heterocyclen und deren verwendung.
ES2032482T3 (es) Derivados del bencilidenamino-, bencilamino- y benzoilamino-imidazol y su empleo como medicamentos. (reserva del art. 167.2 cpe).
ATE139441T1 (de) Verwendung von 2-iminothiazolidin-4-onderivaten als neuartige arzneimittelwirkstoffe
DK613989A (da) Anvendelse af substituerede benzamider til fremstilling af laegemidler med gastromotorisk virkning
DE3865656D1 (de) Trizyklische derivate, agonistn von cholinergetischen rezeptoren und diese enthaltende arzneimittel.
ES2063157T3 (es) Nuevos derivados del indol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ATE70050T1 (de) 1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten.
ES2053787T3 (es) Nuevos derivados del acido aminopimelico, su procedimiento de preparacion y su aplicacion como medicamentos.
ATE2786T1 (de) 1-(2-propynyloxy)-2-amino-3-propanol-aether, ihre herstellung und sie enthaltende pharmazeutische zusammensetzung.
ES2063963T3 (es) Nuevas ariloxi-alquilaminas, su preparacion y medicamentos que las contienen.