ZA90545B - 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents - Google Patents

3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents

Info

Publication number
ZA90545B
ZA90545B ZA90545A ZA90545A ZA90545B ZA 90545 B ZA90545 B ZA 90545B ZA 90545 A ZA90545 A ZA 90545A ZA 90545 A ZA90545 A ZA 90545A ZA 90545 B ZA90545 B ZA 90545B
Authority
ZA
South Africa
Prior art keywords
dihydrobenz
acridine
phenyl
carboxylic acids
chemotherapeutic agents
Prior art date
Application number
ZA90545A
Other languages
English (en)
Inventor
Carl Henry Behrens
Henry Behrens Carl
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of ZA90545B publication Critical patent/ZA90545B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA90545A 1989-01-25 1990-01-25 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents ZA90545B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/301,379 US4918077A (en) 1989-01-25 1989-01-25 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents

Publications (1)

Publication Number Publication Date
ZA90545B true ZA90545B (en) 1991-09-25

Family

ID=23163099

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90545A ZA90545B (en) 1989-01-25 1990-01-25 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents

Country Status (21)

Country Link
US (2) US4918077A (ko)
EP (1) EP0380038B1 (ko)
JP (1) JPH0662572B2 (ko)
KR (1) KR910006985B1 (ko)
AT (1) ATE124399T1 (ko)
AU (1) AU623481B2 (ko)
CA (1) CA2007529A1 (ko)
DE (1) DE69020368T2 (ko)
DK (1) DK0380038T3 (ko)
ES (1) ES2075074T3 (ko)
FI (1) FI95374C (ko)
GR (1) GR3016979T3 (ko)
HU (1) HU205743B (ko)
IE (1) IE68761B1 (ko)
IL (1) IL93161A0 (ko)
MY (1) MY104829A (ko)
NO (1) NO176961C (ko)
NZ (1) NZ232207A (ko)
PT (1) PT92952B (ko)
RU (1) RU1779247C (ko)
ZA (1) ZA90545B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135934A (en) * 1990-07-06 1992-08-04 Du Pont Merck Pharmaceutical Company 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
ATE168679T1 (de) * 1992-04-24 1998-08-15 Kyowa Hakko Kogyo Kk Neue tetracyclische verbindungen
US5807549A (en) * 1993-05-21 1998-09-15 Research Corporation Technologies, Inc. Lymphocyte chemoattractant factor and uses thereof
US5428040A (en) * 1993-08-31 1995-06-27 The Du Pont Merck Pharmaceutical Company Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
DE69430752T2 (de) * 1993-09-28 2002-10-17 Kyowa Hakko Kogyo Co., Ltd. Tetracyclische verbindungen
GB9400585D0 (en) * 1994-01-13 1994-03-09 Guest John D Improvements in or relating to tube couplings
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
AU2896097A (en) * 1996-05-10 1997-12-05 Novartis Ag Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation
US7847125B2 (en) * 2007-11-16 2010-12-07 Chemtura Corporation Acridan derivatives as antioxidants
CN102351870B (zh) * 2011-08-25 2014-03-12 中山大学 一种苯并吖啶衍生物的制备方法及其作为抗癌药物的用途
MX2016006678A (es) 2013-11-22 2016-09-13 Genzyme Corp Nuevos metodos para tratar enfermedades neurodegenerativas.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE502610A (ko) * 1950-04-18
US4680299A (en) * 1984-04-30 1987-07-14 E.I. Du Pont De Nemours And Company 2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof
DE3483704D1 (de) * 1983-07-22 1991-01-17 Du Pont Phenylchinolinsaeure und derivate als antitumormittel.
US4847381A (en) * 1987-08-31 1989-07-11 American Cyanamid Company 2-Phenyl-4-quinoline carboxylic acids

Also Published As

Publication number Publication date
EP0380038B1 (en) 1995-06-28
NO176961C (no) 1995-06-28
HU900255D0 (en) 1990-03-28
FI95374C (fi) 1996-01-25
ES2075074T3 (es) 1995-10-01
AU623481B2 (en) 1992-05-14
DK0380038T3 (da) 1995-08-28
NO176961B (no) 1995-03-20
AU4874590A (en) 1990-08-02
RU1779247C (ru) 1992-11-30
DE69020368T2 (de) 1995-11-09
US4918077A (en) 1990-04-17
IE900267L (en) 1990-07-25
JPH0662572B2 (ja) 1994-08-17
GR3016979T3 (en) 1995-11-30
JPH02233661A (ja) 1990-09-17
IE68761B1 (en) 1996-07-10
DE69020368D1 (de) 1995-08-03
FI900365A0 (fi) 1990-01-24
EP0380038A3 (en) 1991-11-13
EP0380038A2 (en) 1990-08-01
MY104829A (en) 1994-06-30
HU205743B (en) 1992-06-29
KR900011735A (ko) 1990-08-02
FI95374B (fi) 1995-10-13
KR910006985B1 (ko) 1991-09-14
HUT53880A (en) 1990-12-28
US5002954A (en) 1991-03-26
PT92952A (pt) 1990-07-31
NZ232207A (en) 1991-08-27
CA2007529A1 (en) 1990-07-25
IL93161A0 (en) 1990-11-05
PT92952B (pt) 1995-12-29
NO900342L (no) 1990-07-26
ATE124399T1 (de) 1995-07-15
NO900342D0 (no) 1990-01-24

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