AU2896097A - Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation - Google Patents

Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation

Info

Publication number
AU2896097A
AU2896097A AU28960/97A AU2896097A AU2896097A AU 2896097 A AU2896097 A AU 2896097A AU 28960/97 A AU28960/97 A AU 28960/97A AU 2896097 A AU2896097 A AU 2896097A AU 2896097 A AU2896097 A AU 2896097A
Authority
AU
Australia
Prior art keywords
brequinar
xenotransplantation
allografts
derivatives
chronic rejection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU28960/97A
Inventor
Hendrik Schuurman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Publication of AU2896097A publication Critical patent/AU2896097A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
AU28960/97A 1996-05-10 1997-05-09 Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation Abandoned AU2896097A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US64454996A 1996-05-10 1996-05-10
US64454896A 1996-05-10 1996-05-10
US64454796A 1996-05-10 1996-05-10
US08644547 1996-05-10
US08644549 1996-05-10
US08644548 1996-05-10
PCT/EP1997/002401 WO1997042953A1 (en) 1996-05-10 1997-05-09 Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation

Publications (1)

Publication Number Publication Date
AU2896097A true AU2896097A (en) 1997-12-05

Family

ID=27417732

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28960/97A Abandoned AU2896097A (en) 1996-05-10 1997-05-09 Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation

Country Status (2)

Country Link
AU (1) AU2896097A (en)
WO (1) WO1997042953A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102323291B1 (en) 2013-09-24 2021-11-05 기너 라이프 사이언시즈, 인크. System for gas treatment of a cell implant
EP3071199A2 (en) 2013-11-22 2016-09-28 Genzyme Corporation Novel methods for treating neurodegenerative diseases
KR20190086489A (en) 2016-11-15 2019-07-22 기너 라이프 사이언시즈, 인크. Percutaneous gas diffusers suitable for use with subcutaneous implants
CN110831656A (en) 2017-05-04 2020-02-21 吉纳生命科学公司 Robust implantable gas delivery devices and methods, systems, and devices including the same
US11312686B2 (en) 2018-06-22 2022-04-26 Ohio State Innovation Foundation Methods and compositions for inhibition of dihydroorotate dehydrogenase
US20240018108A1 (en) * 2019-12-26 2024-01-18 Ohio State Innovation Foundation Methods and compositions for inhibition of dihydroorotate dehydrogenase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968701A (en) * 1988-04-26 1990-11-06 E. I. Du Pont De Nemours And Company 4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US4918077A (en) * 1989-01-25 1990-04-17 E. I. Du Pont De Nemours & Co., Inc. 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
US5204329A (en) * 1990-06-11 1993-04-20 Du Pont Merck Pharmaceutical Company Treatment of organ transplantation rejection
US5135934A (en) * 1990-07-06 1992-08-04 Du Pont Merck Pharmaceutical Company 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US5578609A (en) * 1994-03-25 1996-11-26 The Dupont Merck Pharmaceutical Company 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
US5523408A (en) * 1994-03-25 1996-06-04 The Dupont Merck Pharmaceutical Company 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents

Also Published As

Publication number Publication date
WO1997042953A1 (en) 1997-11-20

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