ZA905407B - Pyrrolo(2,1-b)thiozle derivatives - Google Patents
Pyrrolo(2,1-b)thiozle derivativesInfo
- Publication number
- ZA905407B ZA905407B ZA905407A ZA905407A ZA905407B ZA 905407 B ZA905407 B ZA 905407B ZA 905407 A ZA905407 A ZA 905407A ZA 905407 A ZA905407 A ZA 905407A ZA 905407 B ZA905407 B ZA 905407B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- substituents
- alkyl group
- moiety
- aryl group
- Prior art date
Links
- 125000001424 substituent group Chemical group 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Detergent Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15114189 | 1989-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA905407B true ZA905407B (en) | 1991-04-24 |
Family
ID=15512262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA905407A ZA905407B (en) | 1989-06-13 | 1990-07-10 | Pyrrolo(2,1-b)thiozle derivatives |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5098919A (xx) |
| EP (1) | EP0410224B1 (xx) |
| JP (1) | JP2875605B2 (xx) |
| KR (1) | KR910002874A (xx) |
| CN (1) | CN1025337C (xx) |
| AT (1) | ATE132870T1 (xx) |
| AU (1) | AU624724B2 (xx) |
| CA (1) | CA2021135A1 (xx) |
| DD (1) | DD296492A5 (xx) |
| DE (1) | DE69024713T2 (xx) |
| DK (1) | DK0410224T3 (xx) |
| ES (1) | ES2084622T3 (xx) |
| FI (1) | FI903511A0 (xx) |
| GR (1) | GR3018798T3 (xx) |
| HU (1) | HU207331B (xx) |
| IE (1) | IE902545A1 (xx) |
| IL (1) | IL95021A (xx) |
| NO (1) | NO903084L (xx) |
| NZ (1) | NZ234450A (xx) |
| PT (1) | PT94688A (xx) |
| RU (2) | RU1836374C (xx) |
| YU (1) | YU136490A (xx) |
| ZA (1) | ZA905407B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050244892A1 (en) * | 2004-02-27 | 2005-11-03 | Lazar Mitchell A | Resistin as a marker and therapeutic target for cardiovascular disease |
| WO2009124978A1 (en) * | 2008-04-09 | 2009-10-15 | Brahms Aktiengesellschaft | Pro-endothelin-1 for the prediction of impaired peak oxygen consumption |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4193926A (en) * | 1974-03-20 | 1980-03-18 | Schering Aktiengesellschaft | 4-(Polyalkoxy phenyl)-2-pyrrolidones |
| US4347186A (en) * | 1980-10-20 | 1982-08-31 | Syntex (U.S.A.) Inc. | Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein |
-
1990
- 1990-07-10 IL IL9502190A patent/IL95021A/en not_active IP Right Cessation
- 1990-07-10 DD DD90342652A patent/DD296492A5/de not_active IP Right Cessation
- 1990-07-10 ZA ZA905407A patent/ZA905407B/xx unknown
- 1990-07-11 AU AU58904/90A patent/AU624724B2/en not_active Ceased
- 1990-07-11 NO NO90903084A patent/NO903084L/no unknown
- 1990-07-11 FI FI903511A patent/FI903511A0/fi not_active Application Discontinuation
- 1990-07-11 KR KR1019900010442A patent/KR910002874A/ko not_active Application Discontinuation
- 1990-07-11 NZ NZ234450A patent/NZ234450A/xx unknown
- 1990-07-12 PT PT94688A patent/PT94688A/pt not_active Application Discontinuation
- 1990-07-12 EP EP90113378A patent/EP0410224B1/en not_active Expired - Lifetime
- 1990-07-12 AT AT90113378T patent/ATE132870T1/de not_active IP Right Cessation
- 1990-07-12 ES ES90113378T patent/ES2084622T3/es not_active Expired - Lifetime
- 1990-07-12 RU SU904830592A patent/RU1836374C/ru active
- 1990-07-12 YU YU136490A patent/YU136490A/sh unknown
- 1990-07-12 DE DE69024713T patent/DE69024713T2/de not_active Expired - Fee Related
- 1990-07-12 DK DK90113378.5T patent/DK0410224T3/da active
- 1990-07-12 IE IE254590A patent/IE902545A1/en unknown
- 1990-07-13 HU HU904214A patent/HU207331B/hu not_active IP Right Cessation
- 1990-07-13 CN CN90107066A patent/CN1025337C/zh not_active Expired - Fee Related
- 1990-07-13 JP JP2186896A patent/JP2875605B2/ja not_active Expired - Fee Related
- 1990-07-13 US US07/552,031 patent/US5098919A/en not_active Expired - Fee Related
- 1990-07-13 CA CA002021135A patent/CA2021135A1/en not_active Abandoned
-
1991
- 1991-08-22 RU SU915001347A patent/RU2026288C1/ru active
-
1996
- 1996-01-25 GR GR960400186T patent/GR3018798T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL95021A0 (en) | 1991-06-10 |
| IL95021A (en) | 1994-06-24 |
| PT94688A (pt) | 1991-03-20 |
| RU2026288C1 (ru) | 1995-01-09 |
| ES2084622T3 (es) | 1996-05-16 |
| CN1049350A (zh) | 1991-02-20 |
| JP2875605B2 (ja) | 1999-03-31 |
| HU904214D0 (en) | 1990-12-28 |
| JPH03128385A (ja) | 1991-05-31 |
| AU5890490A (en) | 1991-01-17 |
| US5098919A (en) | 1992-03-24 |
| EP0410224A1 (en) | 1991-01-30 |
| AU624724B2 (en) | 1992-06-18 |
| CA2021135A1 (en) | 1991-01-14 |
| KR910002874A (ko) | 1991-02-26 |
| HUT57221A (en) | 1991-11-28 |
| DE69024713D1 (de) | 1996-02-22 |
| ATE132870T1 (de) | 1996-01-15 |
| NZ234450A (en) | 1991-10-25 |
| HU207331B (en) | 1993-03-29 |
| DD296492A5 (de) | 1991-12-05 |
| IE902545A1 (en) | 1991-02-27 |
| FI903511A0 (fi) | 1990-07-11 |
| DK0410224T3 (da) | 1996-02-05 |
| NO903084D0 (no) | 1990-07-11 |
| NO903084L (no) | 1991-01-14 |
| EP0410224B1 (en) | 1996-01-10 |
| DE69024713T2 (de) | 1996-06-13 |
| RU1836374C (ru) | 1993-08-23 |
| GR3018798T3 (en) | 1996-04-30 |
| CN1025337C (zh) | 1994-07-06 |
| YU136490A (sh) | 1992-09-07 |
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