ZA90167B - 7-aryl-and heteroaryl ethers of desacetylforskolin,a process for their preparation and their use as medicaments - Google Patents

7-aryl-and heteroaryl ethers of desacetylforskolin,a process for their preparation and their use as medicaments

Info

Publication number
ZA90167B
ZA90167B ZA90167A ZA90167A ZA90167B ZA 90167 B ZA90167 B ZA 90167B ZA 90167 A ZA90167 A ZA 90167A ZA 90167 A ZA90167 A ZA 90167A ZA 90167 B ZA90167 B ZA 90167B
Authority
ZA
South Africa
Prior art keywords
desacetylforskolin
medicaments
aryl
preparation
heteroaryl ethers
Prior art date
Application number
ZA90167A
Other languages
English (en)
Inventor
Raymond Walter Kosley
Walter Kosley Raymond
Gerard J O'malley
J O'malley Gerard
Bettina Spahl
Spahl Bettina
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA90167B publication Critical patent/ZA90167B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
ZA90167A 1989-01-11 1990-01-10 7-aryl-and heteroaryl ethers of desacetylforskolin,a process for their preparation and their use as medicaments ZA90167B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/295,840 US4999351A (en) 1989-01-11 1989-01-11 7-aryl and heteroaryl ethers of desacetylforskolin

Publications (1)

Publication Number Publication Date
ZA90167B true ZA90167B (en) 1991-02-27

Family

ID=23139429

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90167A ZA90167B (en) 1989-01-11 1990-01-10 7-aryl-and heteroaryl ethers of desacetylforskolin,a process for their preparation and their use as medicaments

Country Status (13)

Country Link
US (1) US4999351A (fr)
EP (1) EP0378159A1 (fr)
JP (1) JPH02221271A (fr)
AU (1) AU621448B2 (fr)
CA (1) CA2007513A1 (fr)
FI (1) FI900102A (fr)
HU (1) HUT53631A (fr)
IL (1) IL93019A0 (fr)
NO (1) NO900119L (fr)
NZ (1) NZ232057A (fr)
PH (1) PH26783A (fr)
PT (1) PT92823A (fr)
ZA (1) ZA90167B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177207A (en) * 1989-01-11 1993-01-05 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US6737084B2 (en) 2000-06-27 2004-05-18 Qualilife Compositions and methods for enhancing or treating female sexual response

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557784C2 (de) * 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
DE2640275A1 (de) * 1976-09-08 1978-03-09 Hoechst Ag Pharmakologisch wirksame substanz aus labiaten
DE2654796A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Polyoxygenierte labdan-derivate
US4517200A (en) * 1982-12-27 1985-05-14 Schering-Plough Corporation Method for treating allergic reactions with forskolin
US4564626A (en) * 1983-04-01 1986-01-14 Schering Corporation Methods of inducing bronchodilation
DE3314999A1 (de) * 1983-04-26 1985-03-14 Behringwerke Ag, 3550 Marburg Verwendung des diterpen-derivates forskolin zur immunstimulation
US4476140A (en) * 1983-05-16 1984-10-09 Yale University Composition and method for treatment of glaucoma
DE3407514A1 (de) * 1984-03-01 1985-09-26 Hoechst Ag, 6230 Frankfurt Verwendung von polyoxygenierten labdanderivaten zur behandlung von konstriktionen der atemwege
US4639446A (en) * 1984-12-14 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes, pharmaceutical compositions and use
US4672115A (en) * 1984-12-14 1987-06-09 Hoechst-Roussel Pharmaceuticals Inc. Process for preparing aminoacyllabdanes
DE3502686A1 (de) * 1985-01-26 1986-08-14 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von labdan-derivaten und ihre verwendung als arzneimittel
US4673752A (en) * 1984-12-14 1987-06-16 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes
DE3502685A1 (de) * 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
US4666904A (en) * 1984-12-14 1987-05-19 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes, pharmacuetical compositions and use
US4639443A (en) * 1985-03-01 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
US4677103A (en) * 1985-03-01 1987-06-30 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
US4734513A (en) * 1986-03-31 1988-03-29 Hoechst-Roussel Pharmaceuticals Inc. Method of synthesizing forskolin from 9-deoxyforskolin
US4740522A (en) * 1986-08-28 1988-04-26 Hoechst-Roussel Pharmaceuticals Inc. Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure
DE3730748A1 (de) * 1987-06-06 1988-12-22 Hoechst Ag Neue polyoxygenierte labdanderivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3887212T2 (de) * 1987-06-29 1994-06-01 Nippon Kayaku Kk Verfahren zur Herstellung von Derivaten von 6,7-Diazyl-7-desacetylforskolin.
DE3737353A1 (de) * 1987-11-04 1989-05-18 Hoechst Ag Neue acyllabdan-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
IL93019A0 (en) 1990-11-05
JPH02221271A (ja) 1990-09-04
HU900099D0 (en) 1990-03-28
PT92823A (pt) 1990-07-31
US4999351A (en) 1991-03-12
AU621448B2 (en) 1992-03-12
FI900102A0 (fi) 1990-01-09
NO900119L (no) 1990-07-12
HUT53631A (en) 1990-11-28
NO900119D0 (no) 1990-01-10
CA2007513A1 (fr) 1990-07-11
EP0378159A1 (fr) 1990-07-18
FI900102A (fi) 1990-07-12
PH26783A (en) 1992-10-13
NZ232057A (en) 1991-10-25
AU4783790A (en) 1990-07-19

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