ZA898440B - Lactamimides in the treatment of drug-resistant protozoal infections - Google Patents

Lactamimides in the treatment of drug-resistant protozoal infections

Info

Publication number
ZA898440B
ZA898440B ZA898440A ZA898440A ZA898440B ZA 898440 B ZA898440 B ZA 898440B ZA 898440 A ZA898440 A ZA 898440A ZA 898440 A ZA898440 A ZA 898440A ZA 898440 B ZA898440 B ZA 898440B
Authority
ZA
South Africa
Prior art keywords
drug
treatment
lactamimides
resistant
protozoal infections
Prior art date
Application number
ZA898440A
Other languages
English (en)
Inventor
Alan Joseph Bitoni
Joseph Bitoni Alan
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA898440B publication Critical patent/ZA898440B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA898440A 1988-11-10 1989-11-06 Lactamimides in the treatment of drug-resistant protozoal infections ZA898440B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26985888A 1988-11-10 1988-11-10

Publications (1)

Publication Number Publication Date
ZA898440B true ZA898440B (en) 1990-07-25

Family

ID=23028945

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA898440A ZA898440B (en) 1988-11-10 1989-11-06 Lactamimides in the treatment of drug-resistant protozoal infections

Country Status (11)

Country Link
EP (1) EP0370320B1 (de)
JP (1) JPH02256614A (de)
AT (1) ATE81004T1 (de)
AU (1) AU619613B2 (de)
DE (1) DE68903092T2 (de)
DK (1) DK561089A (de)
ES (1) ES2045348T3 (de)
GR (1) GR3006349T3 (de)
IE (1) IE893618L (de)
PH (1) PH27568A (de)
ZA (1) ZA898440B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ228748A (en) * 1988-04-20 1991-07-26 Merrell Dow Pharma Treating drug-resistant protozoal infections with a tricyclic compound and an antiprotozoal agent: composition and kit therefor
PT724435E (pt) * 1993-10-21 2002-11-29 Searle & Co Derivados amidino uteis como inibidores de oxido nitrico sintase
RU2136661C1 (ru) * 1993-10-21 1999-09-10 Джи Ди Сирл энд Ко. Амидинопроизводные, их применение и фармацевтическая композиция
DE69518631T2 (de) * 1994-03-10 2001-01-11 Searle & Co L-n6-(1-iminoethyl)lysin - derivate und ihre verwendung als no-synthase - inhibitoren
US5684008A (en) * 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
US6011028A (en) * 1995-04-20 2000-01-04 G.D. Searle & Co. Cyclic amidino agents useful as nitric oxide synthase inhibitors
US5830917A (en) * 1995-09-11 1998-11-03 G. D. Searle & Co. L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors
US5981511A (en) * 1996-03-06 1999-11-09 G.D. Searle & Co. Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
US5981556A (en) * 1997-07-22 1999-11-09 G.D. Searle & Co. 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors
CA2333691A1 (en) 1998-06-10 1999-12-16 G.D. Searle & Co. Heterobicyclic and tricyclic nitric oxide synthase inhibitors
US6344473B1 (en) 2000-08-07 2002-02-05 G.D. Searle & Co. Imidazoles useful as nitric oxide synthase inhibitors
JP2012502009A (ja) * 2008-09-09 2012-01-26 ビーエーエスエフ ソシエタス・ヨーロピア 動物有害生物を駆除するためのピロリン−２−イルアミノ化合物
CA2746295A1 (en) * 2008-12-08 2010-07-08 Allergan, Inc. N-(1-phenyl-2-arylethyl)-4,5-dihydro-3h-pyrrol-2-amine compounds as subtype selective modulators of alpha2b or alpha2b and alpha2c adrenoceptors
WO2011042565A2 (en) * 2009-10-09 2011-04-14 Instituut Voor Tropische Geneeskunde Antiprotozoal activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228130A (en) * 1978-10-23 1980-10-14 The B. F. Goodrich Company Coating polymerization reactors with oligomers derived from polyhydric phenols plus a bleach

Also Published As

Publication number Publication date
PH27568A (en) 1993-08-18
EP0370320B1 (de) 1992-09-30
ES2045348T3 (es) 1994-01-16
JPH02256614A (ja) 1990-10-17
DK561089A (da) 1990-05-11
IE893618L (en) 1990-05-10
DE68903092D1 (de) 1992-11-05
GR3006349T3 (de) 1993-06-21
DK561089D0 (da) 1989-11-09
AU4445089A (en) 1990-05-17
DE68903092T2 (de) 1993-02-18
AU619613B2 (en) 1992-01-30
ATE81004T1 (de) 1992-10-15
EP0370320A1 (de) 1990-05-30

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