ZA898025B - 3beta,17beta-hydroxy-substituted steroids and related steroidal compounds - Google Patents

3beta,17beta-hydroxy-substituted steroids and related steroidal compounds

Info

Publication number
ZA898025B
ZA898025B ZA898025A ZA898025A ZA898025B ZA 898025 B ZA898025 B ZA 898025B ZA 898025 A ZA898025 A ZA 898025A ZA 898025 A ZA898025 A ZA 898025A ZA 898025 B ZA898025 B ZA 898025B
Authority
ZA
South Africa
Prior art keywords
compounds
hydroxy
17beta
3beta
steroidal compounds
Prior art date
Application number
ZA898025A
Other languages
English (en)
Inventor
John O'neal Johnston
O'neal Johnston John
Gene Warwick Holbert
Warwick Holbert Gene
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA898025B publication Critical patent/ZA898025B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Silicon Polymers (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA898025A 1988-10-27 1989-10-23 3beta,17beta-hydroxy-substituted steroids and related steroidal compounds ZA898025B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/263,091 US4882322A (en) 1988-10-27 1988-10-27 3β,17β-hydroxy-substituted steroids and related steroidal compounds

Publications (1)

Publication Number Publication Date
ZA898025B true ZA898025B (en) 1990-07-25

Family

ID=23000340

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA898025A ZA898025B (en) 1988-10-27 1989-10-23 3beta,17beta-hydroxy-substituted steroids and related steroidal compounds

Country Status (18)

Country Link
US (1) US4882322A (de)
EP (1) EP0366144B1 (de)
JP (1) JP2750621B2 (de)
KR (1) KR900006360A (de)
CN (1) CN1042363A (de)
AT (1) ATE111478T1 (de)
AU (1) AU619608B2 (de)
CA (1) CA2001264C (de)
DE (1) DE68918219T2 (de)
DK (1) DK533189A (de)
ES (1) ES2063801T3 (de)
FI (1) FI895084A0 (de)
HU (1) HU204065B (de)
IL (1) IL92103A0 (de)
NO (1) NO173097C (de)
NZ (1) NZ231107A (de)
PT (1) PT92113B (de)
ZA (1) ZA898025B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166201A (en) * 1990-11-30 1992-11-24 Merrell Dow Pharmaceuticals Inc. 2β,19-ethylene bridged steroids as aromatase inhibitors
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
US20070099880A1 (en) * 2003-11-24 2007-05-03 Blizzard Timothy A Estrogen receptor modulators
EP1689768A2 (de) * 2003-11-24 2006-08-16 Merck & Co., Inc. Östrogenrezeptormodulatoren
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
CN103555806B (zh) * 2013-11-16 2015-05-13 江南大学 一种高效利用亚麻刺盘孢霉合成7α-羟基-雄甾烯酮的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
GB8531747D0 (en) * 1985-12-24 1986-02-05 Erba Farmitalia 10beta-alkynylestrene derivatives

Also Published As

Publication number Publication date
DK533189D0 (da) 1989-10-26
FI895084A0 (fi) 1989-10-26
ATE111478T1 (de) 1994-09-15
NO894276L (no) 1990-04-30
HU204065B (en) 1991-11-28
NO894276D0 (no) 1989-10-26
PT92113B (pt) 1995-06-30
DE68918219D1 (de) 1994-10-20
CN1042363A (zh) 1990-05-23
DK533189A (da) 1990-04-28
HU895457D0 (en) 1990-01-28
JP2750621B2 (ja) 1998-05-13
AU4367989A (en) 1990-05-31
IL92103A0 (en) 1990-07-12
US4882322A (en) 1989-11-21
DE68918219T2 (de) 1995-02-02
JPH02174793A (ja) 1990-07-06
KR900006360A (ko) 1990-05-08
NZ231107A (en) 1992-03-26
HUT52113A (en) 1990-06-28
CA2001264C (en) 2001-05-01
EP0366144A1 (de) 1990-05-02
ES2063801T3 (es) 1995-01-16
EP0366144B1 (de) 1994-09-14
NO173097B (no) 1993-07-19
AU619608B2 (en) 1992-01-30
CA2001264A1 (en) 1990-04-27
NO173097C (no) 1993-10-27
PT92113A (pt) 1990-04-30

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