ZA897532B - Basic 4-aryl-dhp amides,processes for their preparation and their use in medicaments - Google Patents

Basic 4-aryl-dhp amides,processes for their preparation and their use in medicaments

Info

Publication number
ZA897532B
ZA897532B ZA897532A ZA897532A ZA897532B ZA 897532 B ZA897532 B ZA 897532B ZA 897532 A ZA897532 A ZA 897532A ZA 897532 A ZA897532 A ZA 897532A ZA 897532 B ZA897532 B ZA 897532B
Authority
ZA
South Africa
Prior art keywords
dhp
medicaments
amides
aryl
basic
Prior art date
Application number
ZA897532A
Other languages
English (en)
Inventor
Juergen Stoltefuss
Stoltefuss Juergen
Eckhard Schwenner
Schwenner Eckhard
Rainer Gross
Gross Rainer
Siegbert Hebisch
Hebisch Siegbert
Matthias Schramm
Schramm Matthias
Martin Bechem
Bechem Martin
Claudia Hirth
Hirth Claudia
Johannes-Peter Stasch
Stasch Johannes-Peter
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA897532B publication Critical patent/ZA897532B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
ZA897532A 1988-10-05 1989-10-04 Basic 4-aryl-dhp amides,processes for their preparation and their use in medicaments ZA897532B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3833892A DE3833892A1 (de) 1988-10-05 1988-10-05 Basische 4-aryl-dhp-amide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ZA897532B true ZA897532B (en) 1990-06-27

Family

ID=6364449

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897532A ZA897532B (en) 1988-10-05 1989-10-04 Basic 4-aryl-dhp amides,processes for their preparation and their use in medicaments

Country Status (16)

Country Link
US (1) US5015650A (pt)
EP (1) EP0362632A3 (pt)
JP (1) JPH02169572A (pt)
KR (1) KR900006289A (pt)
CN (1) CN1041758A (pt)
AU (1) AU616801B2 (pt)
CA (1) CA2000081A1 (pt)
DD (2) DD296683A5 (pt)
DE (1) DE3833892A1 (pt)
DK (1) DK489889A (pt)
FI (1) FI894677A (pt)
HU (1) HUT52055A (pt)
IL (1) IL91863A0 (pt)
NO (1) NO893756L (pt)
PT (1) PT91884A (pt)
ZA (1) ZA897532B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833893A1 (de) * 1988-10-05 1990-04-12 Bayer Ag Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte
NL9001752A (nl) * 1990-08-02 1992-03-02 Cedona Pharm Bv Nieuwe 1,4-dihydropyridinederivaten.
DE4100125A1 (de) * 1991-01-04 1992-07-09 Bayer Ag Neue dihydropyridinamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
WO2009041504A1 (ja) * 2007-09-25 2009-04-02 Arkray, Inc. 分光測定用ペレット、その製造方法および分光測定方法
US10513515B2 (en) 2017-08-25 2019-12-24 Biotheryx, Inc. Ether compounds and uses thereof
US11236103B2 (en) 2018-07-27 2022-02-01 Biotheryx, Inc. Bifunctional compounds
EP4143329A4 (en) 2020-04-28 2024-10-16 Anwita Biosciences Inc INTERLEUKIN-2 POLYPEPTIDES AND FUSION PROTEINS THEREOF, AS WELL AS THEIR PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2228377A1 (de) * 1972-06-10 1974-01-03 Bayer Ag Dihydropyridin-carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
DE3445852A1 (de) * 1984-12-15 1986-06-19 Bayer Ag, 5090 Leverkusen Dihydropyridin-carbonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3521761A1 (de) * 1985-06-19 1987-01-02 Bayer Ag Neue 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
JPS62174050A (ja) * 1985-10-21 1987-07-30 Nippon Shoji Kk 3−アミノカルボニル−1,4−ジヒドロピリジン−5−カルボン酸誘導体、その製法および医薬組成物
DE3601397A1 (de) * 1986-01-18 1987-07-23 Bayer Ag Substituierte 1,4-dihydropyridin-3-carbonsaeurepiperazide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3711991A1 (de) * 1987-04-09 1988-10-20 Bayer Ag Dihydropyridinamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3833893A1 (de) * 1988-10-05 1990-04-12 Bayer Ag Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte

Also Published As

Publication number Publication date
DD296683A5 (de) 1991-12-12
EP0362632A3 (de) 1990-11-07
DK489889A (da) 1990-04-06
FI894677A0 (fi) 1989-10-03
AU616801B2 (en) 1991-11-07
CN1041758A (zh) 1990-05-02
AU4260989A (en) 1990-04-12
US5015650A (en) 1991-05-14
DD297813A5 (de) 1992-01-23
JPH02169572A (ja) 1990-06-29
NO893756D0 (no) 1989-09-21
EP0362632A2 (de) 1990-04-11
DE3833892A1 (de) 1990-04-12
IL91863A0 (en) 1990-06-10
NO893756L (no) 1990-04-06
CA2000081A1 (en) 1990-04-05
KR900006289A (ko) 1990-05-07
FI894677A (fi) 1990-04-06
HUT52055A (en) 1990-06-28
PT91884A (pt) 1990-04-30
DK489889D0 (da) 1989-10-04

Similar Documents

Publication Publication Date Title
IL88182A0 (en) Derivatives of 1-desoxynojirimicyin and 1-desoxymannonojirimycin,their preparation and their use in medicaments
ZA917853B (en) 2-aminopyrimidine-4-carboxamide derivatives,their preparation and their use in therapy
ZA885150B (en) N-aminobutyl-n-phenylarylamide derivatives,their preparation and their application in therapy
EP0449026A3 (en) Desoxynojirimycin derivatives, process for their preparation and their use in drugs
ZA903409B (en) Maleinimide-derivatives and their use as pharmaceuticals
ZA897532B (en) Basic 4-aryl-dhp amides,processes for their preparation and their use in medicaments
ZA866683B (en) Dihydropyridine-2-hydroxyamines,process for their preparation and their use in medicaments
ZA899528B (en) Adenosin derivatives,their preparation and use
ZA888234B (en) New fluoromethoxyphenyl dihydropyridines,processes for the preparation and their use in medicaments
ZA856595B (en) New,1,4-dishydropyridines,processes for their preparation,and their use in medicaments
PH25293A (en) Pyrazol and indazolpyridin amines and their use as medicaments
ZA924127B (en) New hetaryloxy-beta-carbolines,their production and use in pharmaceutical agents
IL92281A0 (en) Polyimidesiloxanes,their preparation and use
IL86218A0 (en) Alkyl-n-aryl-tetrahydrophthalimides,processes for their preparation and their use in plant protection
ZA898480B (en) Phenyloxypropanolamine derivatives,their preparation and their application in therapeutics
IL90000A0 (en) Benzothiazepin-4-one derivatives,their preparation and their application in therapy
NZ229274A (en) 1,2-dithiol-3-thion-s-oxides and liver-protective medicaments
ZA904290B (en) 1-phenyl-1,4-dihydro-3-amino-4-oxopyridazine derivatives,their preparation and their application in therapy
ZA864874B (en) New benzamides,process for their preparation and their application in the pharmaceutical field
ZA905464B (en) Anti-infective agents,process for their preparation and their use in therapy
NZ230921A (en) 3-phenyloxymethyl-cephalosporin derivatives and medicaments
ZA878324B (en) New 2,6-diamino-3-halobenzylpyridines and processes for their manufacture as well as their use in pharmaceuticals
ZA927154B (en) Indolesulphonamide-substituted dihydropyridines, processes for their preparation and their use in medicaments.
ZA888235B (en) New fluoromethoxyphenyl dihydropyridines,processes for their preparation and their use in medicaments
ZA858249B (en) 1,4-dihydropyridine-hydroxyamines,a process for their preparation and their use in medicaments