ZA897349B - (-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing it - Google Patents

(-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing it

Info

Publication number
ZA897349B
ZA897349B ZA897349A ZA897349A ZA897349B ZA 897349 B ZA897349 B ZA 897349B ZA 897349 A ZA897349 A ZA 897349A ZA 897349 A ZA897349 A ZA 897349A ZA 897349 B ZA897349 B ZA 897349B
Authority
ZA
South Africa
Prior art keywords
methyl
aminoethoxy
methoxycarbonyl
ethoxy
dihydropyridine
Prior art date
Application number
ZA897349A
Other languages
English (en)
Inventor
Jean-Louis Peglion
Peglion Jean-Louis
Yves-Michel Gargouil
Gargouil Yves-Michel
Jean-Paul Vilaine
Vilaine Jean-Paul
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA897349B publication Critical patent/ZA897349B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA897349A 1989-07-04 1989-09-27 (-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing it ZA897349B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8908920A FR2649395B1 (fr) 1989-07-04 1989-07-04 Nouveau derive de la dihydro-1,4 pyridine denomme (-) Ÿi1Ÿ(((amino-2 ethoxy)-2 ethoxy) methylŸi1Ÿ) -2 (dichloro-2,3 phenyl)-4 ethoxycarbonyl-3 methoxycarbonyl-5 methyl-6 dihydro-1,4 pyridine, son procede de preparation et les compositions qui le contiennent

Publications (1)

Publication Number Publication Date
ZA897349B true ZA897349B (en) 1990-09-26

Family

ID=9383413

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897349A ZA897349B (en) 1989-07-04 1989-09-27 (-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing it

Country Status (14)

Country Link
EP (1) EP0406502B1 (pt)
JP (1) JPH0720934B2 (pt)
AT (1) ATE122340T1 (pt)
AU (1) AU619049B2 (pt)
CA (1) CA1327582C (pt)
DE (1) DE68922605T2 (pt)
DK (1) DK478989A (pt)
ES (1) ES2074472T3 (pt)
FR (1) FR2649395B1 (pt)
IE (1) IE67059B1 (pt)
NZ (1) NZ230854A (pt)
OA (1) OA09136A (pt)
PT (1) PT91869B (pt)
ZA (1) ZA897349B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2652083B1 (fr) * 1989-09-20 1992-01-24 Ador Cie Nouveau procede de separation d'isomeres optiques des derives de la dihydro-1,4 pyridine.
FR2686879B1 (fr) * 1992-02-05 1994-03-18 Adir Cie Nouveaux composes de 1,4-dihydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant.
DE4444864A1 (de) * 1994-12-16 1996-06-20 Bayer Ag Verwendung von 5-Acyl-1,4-dihydropyridinen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
FR2602231B1 (fr) * 1986-08-04 1988-10-28 Adir Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
IE67059B1 (en) 1996-02-21
IE893103A1 (en) 1991-01-16
CA1327582C (fr) 1994-03-08
PT91869A (pt) 1991-03-20
FR2649395A1 (fr) 1991-01-11
PT91869B (pt) 1995-07-18
JPH0344371A (ja) 1991-02-26
NZ230854A (en) 1991-02-26
DK478989A (da) 1991-01-05
OA09136A (fr) 1991-10-31
DE68922605T2 (de) 1996-01-04
FR2649395B1 (fr) 1992-11-06
ATE122340T1 (de) 1995-05-15
EP0406502B1 (fr) 1995-05-10
DE68922605D1 (de) 1995-06-14
DK478989D0 (da) 1989-09-28
AU4239089A (en) 1991-01-10
JPH0720934B2 (ja) 1995-03-08
EP0406502A1 (fr) 1991-01-09
ES2074472T3 (es) 1995-09-16
AU619049B2 (en) 1992-01-16

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